Preliminary Study on Chemical Speciation of Sulphur in Cancerous Tissues

• Authors: W Kwiatek , A Banaś , K Banaś , A Kisiel , G Cinque , G Falkenberg
• Languages of publication: EN

Abstracts

EN

Sulphur is vital for almost all living organisms by participating in a wide variety of metabolic processes. Nevertheless its biochemistry is only partially understood, due to it a few tools such as X-ray absorption near edge structure may be used to determine its chemical speciation in biological system. In this paper we focused on analysis of composition and elemental distribution in tissue structures of biological samples. We examined cancerous and non-cancerous prostate tissues. Experiments were carried out on the L-beam line at the HASYLAB, DESY (Hamburg, Germany) and DAΦNE-Light Facility at the Laboratori Nationali di Frascati (Frascati, Italy). Synchrotron radiation induced X-ray emission measurements reveal the significant differences in concentration of sulphur between cancerous and non-cancerous tissues. X-ray absorption near edge structure spectra show two main types of sulphur that are represented by X-ray peaks at 2476 eV and 2484 eV. This suggests that different sulphur components are present in the measured samples.

Keywords

EN

87.64.Gb

• Publisher: Institute of Physics, Polish Academy of Sciences
• Journal: Acta Physica Polonica A
• Year: 2006
• Volume: 109
• Issue: 3
• Pages: 383-387

Dates

published

2006-03

received

2005-05-20

Contributors

author

W Kwiatek

• Institute of Nuclear Physics, Radzikowskiego 152, 31-342 Kraków, Poland

author

A Banaś

• Institute of Nuclear Physics, Radzikowskiego 152, 31-342 Kraków, Poland

author

K Banaś

• Institute of Nuclear Physics, Radzikowskiego 152, 31-342 Kraków, Poland

author

A Kisiel

• Institute of Physics, Jagiellonian University, Reymonta 4, 30-059 Kraków, Poland

author

G Cinque

• Laboratori Nationali di Frascati (LNF), via E. Fermi 40, 00044 Frascati (Rome), Italy

author

G Falkenberg

• HASYLAB, DESY, Notkestraße 85, 22603 Hamburg, Germany

References

• 1. J.R. Landolph, in: Metal Ions in Biological Systems, Eds. H. Sigel, A. Sigel, Vol. 36, Marcel Dekker, New York 1999, p 445
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• 3. K.S. Kasprzak, Free Radical Biology& Medicine, 32, 958, 2002
• 4. A. Banaś, K. Banaś, G. Falkenberg, G. Dyduch, W.M. Kwiatek, Acta Phys. Pol. A, 109, 323, 2006
• 5. http://www.lnf.infn.it
• 6. B. Gilbert, L. Perfetti, O. Fauchoux, J. Redondo, P.A. Baudat, R. Andres, M. Neumann, S. Steen, D. Gabel, D. Mercanti, M.T. Ciotti, P. Perfetti, G. Margaritondo, G. De Stasio, Phys. Rev. E, 62, 1110, 2000

Identifiers

DOI

10.12693/APhysPolA.109.383