Distinguishing Prostate Cancer from Hyperplasia

• Authors: W Kwiatek , A Banaś , K Banaś , M Podgórczyk , G Dyduch , G Falkenberg , M Gajda , T Cichocki
• Languages of publication: EN

Abstracts

EN

The prostate gland is the most common site of neoplastic disorders in men. The knowledge of the pathogenesis of benign prostate hyperplasia and prostate cancer is still under investigation. X-ray fluorescence analysis using synchrotron radiation seems to be an appropriate technique to study the elemental composition of biological tissues. The measurements presented in this paper were carried out on the L-beam line at the HASYLAB, DESY (Germany). The observed concentrations of Fe, Cu, Mn, and Zn are significantly higher in cancerous tissues, as compared to normal and hyperplastic ones. Our results reveal also the existence of the two types of hyperplasia.

Keywords

EN

87.64.-t

Discipline

• 87.64.-t: Spectroscopic and microscopic techniques in biophysics and medical physics

• Publisher: Institute of Physics, Polish Academy of Sciences
• Journal: Acta Physica Polonica A
• Year: 2006
• Volume: 109
• Issue: 3
• Pages: 377-381

Dates

published

2006-03

received

2005-05-20

Contributors

author

W Kwiatek

• Institute of Nuclear Physics, Radzikowskiego 152, 31-342 Krakó Poland

author

A Banaś

• Institute of Nuclear Physics, Radzikowskiego 152, 31-342 Krakó Poland

author

K Banaś

• Institute of Nuclear Physics, Radzikowskiego 152, 31-342 Krakó Poland

author

M Podgórczyk

• Institute of Nuclear Physics, Radzikowskiego 152, 31-342 Krakó Poland

author

G Dyduch

• Dept. of Pathomorphology, Collegium Medicum, Jagiellonian University, Grzegórzecka 16, 31-034 Kraków, Poland

author

G Falkenberg

• HASYLAB, DESY, Notkestraße 85, 22603 Hamburg, Germany

author

M Gajda

• Dept. of Histology, Collegium Medicum, Jagiellonian University, Kopernika 7, 31-034 Kraków, Poland

author

T Cichocki

• Dept. of Histology, Collegium Medicum, Jagiellonian University, Kopernika 7, 31-034 Kraków, Poland

References

• 1. O.A. Ozen, M. Yaman, M. Sarsilmaz, J. Trace Elem. Med. Biol., 16, 119, 2003
• 2. http://www-hasylab.desy.de
• 3. W.M. Kwiatek, Postdoctoral Thesis (Habilitation), Institute of Nuclear Physics, PAS, Kraków 2003, Raport No. 1928/L (in Polish)
• 4. W.M. Kwiatek, A. Banaś, M. Gajda, M. Galka, T. Cichocki, Annual Report 2002, 2003, 2004, Publ.:HASYLAB, Hamburg (Germany) 2002, 2003, 2004
• 5. A. Banaś, PhD thesis, Institute of Physics, Jagiellonian University, Kraków 2005 (in Polish)

Identifiers

DOI

10.12693/APhysPolA.109.377