Spread and survival of promiscuous IncP-1 plasmids

• Authors: Małgorzata Adamczyk , Grażyna Jagura-Burdzy
• Languages of publication: EN

Abstracts

EN

Plasmids classified to the IncP-1 incompatibility group belong to the most stably maintained mobile elements among low copy number plasmids known to date. The remarkable persistence is achieved by various tightly controlled stability mechanisms like active partitioning, efficient conjugative transfer system, killing of plasmid-free segregants and multimer resolution. The unique feature of IncP-1 plasmids is the central control operon coding for global regulators which control the expression of genes involved in vegetative replication, stable maintenance and conjugative transfer. The multivalent regulatory network provides means for coordinated expression of all plasmid functions. The current state of knowledge about two fully sequenced plasmids RK2 and R751, representatives of the IncP-1α and IncP-1β subgroups, is presented.

Keywords

EN

stable maintenance; IncP-1 plasmids; central control region; global regulation

• Publisher: Polish Biochemical Society
• Journal: Acta Biochimica Polonica
• Year: 2003
• Volume: 50
• Issue: 2
• Pages: 425-453

Dates

published

2003

received

2003-05-28

accepted

2003-06-12

Contributors

author

Małgorzata Adamczyk

• Department of Microbial Biochemistry, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warszawa, Poland

author

Grażyna Jagura-Burdzy

• Department of Microbial Biochemistry, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warszawa, Poland

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