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2003 | 50 | 2 | 461-469

Article title

Novel properties of antimicrobial peptides.

Content

Title variants

Languages of publication

EN

Abstracts

EN
Endogenous peptide antibiotics are known as evolutionarily old components of innate immunity. Due to interaction with cell membrane these peptides cause permeabilization of the membrane and lysis of invading microbes. However, some studies proved that antimicrobial peptides are universal multifunctional molecules and their functions extend far beyond simple antibiotics. In this review we present an overview of the general mechanism of action of antimicrobial peptides and discuss some of their additional properties, like antitumour activity, mitogenic activity, role in signal transduction pathways and adaptive immune response.

Year

Volume

50

Issue

2

Pages

461-469

Physical description

Dates

published
2003
received
2002-12-18
revised
2003-04-23
accepted
2003-05-16

Contributors

  • Department of Physical Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, Gdańsk, Poland
author
  • Division of Cell Biology, Department of Histology and Immunology, Intercollegiate Faculty of Biotechnology, Medical University of Gdańsk, Gdańsk, Poland
  • Department of Physical Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, Gdańsk, Poland

References

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Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.bwnjournal-article-abpv50i2p461kz
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