Novel side reactions accompanying activation and aminolysis of N-benzoyl-2-alkylserines.

• Authors: Zbigniew J Kamiński , Agnieszka Woszczyna , Beata Kolesińska , Adam Redliński
• Languages of publication: EN

Abstracts

EN

2-Phenyl-4-alkyl-4-hydroxymethyl-1,3-oxazolones (2a-d) have been identified as side products accompanying activation of N-benzoyl-2-alkylserines (1a-d). Oxazolones 2a-d in the presence of amine rearrange subsequently to corresponding 4-alkyl-2-phenyl-4,5-dihydro-1,3-oxazole-5 carboxylic acids (4a-d) at a 20-68% yield.

Keywords

EN

side-reaction; 4-alkyl-2-phenyl-4,5-dihydro-1,3-oxazole-5 carboxylic acids; 2-alkylserines

• Publisher: Polish Biochemical Society
• Journal: Acta Biochimica Polonica
• Year: 2001
• Volume: 48
• Issue: 4
• Pages: 1175-1178

Dates

published

2001

received

2001-09-26

accepted

2001-11-20

Contributors

author

Zbigniew J Kamiński

• Institute of Organic Chemistry, Technical University of Łódź, 90-924 Łódź, Poland

author

Agnieszka Woszczyna

• Institute of Organic Chemistry, Technical University of Łódź, 90-924 Łódź, Poland

author

Beata Kolesińska

• Institute of Organic Chemistry, Technical University of Łódź, 90-924 Łódź, Poland

author

Adam Redliński

• Institute of Organic Chemistry, Technical University of Łódź, 90-924 Łódź, Poland

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