Self-organizing neural network for modeling 3D QSAR of colchicinoids.

• Authors: Jarosław Polański
• Languages of publication: EN

Abstracts

EN

A novel scheme for modeling 3D QSAR has been developed. A method involving multiple self-organizing neural network adjusted to be analyzed by the PLS (partial least squares) analysis was used to model 3D QSAR of the selected colchicinoids. The model obtained allows the identification of some structural determinants of the biological activity of compounds.

Keywords

EN

neural networks; 3D QSAR; colchicinoids

• Publisher: Polish Biochemical Society
• Journal: Acta Biochimica Polonica
• Year: 2000
• Volume: 47
• Issue: 1
• Pages: 37-45

Dates

published

2000

received

1999-10-25

Contributors

author

Jarosław Polański

• Department of Organic Chemistry, Institute of Chemistry, University of Silesia, 40-006 Katowice, Poland

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