Invasive fungal infection in an acute myeloid leukaemia patient

• Authors: Magdalena Szczepańska , Grzegorz Charliński
• Languages of publication: EN

Abstracts

EN

Invasive fungal infections (IFI) are one of the most severe complications of treatment in patients with acute myeloid leukaemia (AML) that are diagnosed during the myelosuppression period following intensive chemotherapy. Due to a high mortality rate reaching up to 30–70%, IFI require an adequate prevention, and once an active infection is diagnosed – a rapid diagnosis and an effective antifungal therapy. Modern therapy models are based on expensive treatment regimens and are often associated with long-term hospitalization and the need for intensive supportive treatment.

Keywords

EN

diagnostic tests; invasive fungal infections; prophylaxis; treatment

Discipline

• MEDICINE: MEDICINE

• Publisher: Medical Education
• Journal: OncoReview
• Year: 2016
• Volume: 6
• Issue: 4
• Pages: A175-178

Contributors

author

Magdalena Szczepańska

• Haematology Ward, Nicolaus Copernicus Specialist Hospital in Toruń, Poland

author

Grzegorz Charliński

• Haematology Ward, Nicolaus Copernicus Specialist Hospital in Toruń, Poland

References

• 1. Pagano L, Caira M, Candoni A et al. The epidemiology of fungal infections in patients with hematologic malignancies: the SEIFEM – 2004 study. Haematologica 2006; 91: 1068-1075.
• 2. Bhatt VR, Viola GM, Ferrajoli A. Invasive Fungal Infections in Acute Leukemia. Ther Adv Hematol 2011; 2(4): 231-247.
• 3. Leroux S, Ullmann AJ. Management and diagnostic guidelines for fungal diseases in infectious diseases and clinical microbiology: critical appraisal. Clin Microbiol Infect 2013; 19(12): 1115-1121.
• 4. Czyż A. Powikłania infekcyjne w hematologii. Hematologia 2016; 1(10): 108-118.
• 5. Maertens J, Marchetti O, Herbrecht R et al; Third European Conference on Infections in Leukemia: European guidelines for antifungal management in leukaemia and hematopoietic stem cell transplant recipients: summary of the ECIL 3-2009 update. Bone Marrow Transplant 2012; 47: 846-854.

• Document Type: article