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2010 | 15 | 97 - 106
Article title

POROUS CHITOSAN STRUCTURES FOR MEDICAL APPLICATIONS

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Languages of publication
EN
Abstracts
EN
The aim of the study was to develop preparation methods of porous chitosan structures and to investigate their morphological properties as well as the kinetics of model substance release (salicylic acid). Chitosan scaffolds were generated using the liophylisation method and the systems obtained were saturated with hydroxyapatite and salicylic acid. Microscopic investigations (optical and electron microscopy) were carried out to examine the morphology of structures and water vapour sorption isotherms were determined to define the influence of hydroxyapatite on the system sorption ability. Additionally, the kinetic curve for the model substance release process (the process of the 1st order) was determined.
Publisher

Year
Volume
15
Pages
97 - 106
Physical description
Contributors
  • Faculty of Process and Environmental Engineering, Technical University of Lodz, ul. Wolczanska 213, 90-924, Lodz, Poland, suppler@o2.pl
author
  • Faculty of Process and Environmental Engineering, Technical University of Lodz, ul. Wolczanska 213, 90-924, Lodz, Poland
References
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  • Wan Y., Wu H., Cao X., Dalai S.; (2008) Compressive mechanical properties and biodegradability porous poly(caprolactone)/chitosan scaffolds. Polymer Degradation and Stability. 93(10), pp. 1736–1741.
  • Chu T-M. G., Orton D.G., Hollister S.J., Feinberg S.E., Halloran J.W.; (2002) Mechanical and in vivo performance of hydroxyapatite implants with controlled architectures. Biomaterials 23(5), pp. 1283–1293.
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Document Type
article
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.psjd-f3ba8fee-3ade-48a8-8b7c-16aa82ec9339
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