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2018 | 96 | 108-119
Article title

The influence of selected active substances on the functioning of the visual system

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EN
Abstracts
EN
Age-related macular degeneration (AMD), glaucoma and cataracts are the most common eye diseases. They are predominantly caused by insufficient amounts of antioxidants in the body, which include lutein, zeaxanthin, lycopene, omega-3 fatty acids, vitamins and micronutrients. The positive properties of these biologically active substances affect the neutralization of reactive oxygen species, slow absorption of UV radiation, and improve blood supply to the structural elements of the eye. Deficiency of these substances has a negative effect on the functioning of the eye, leading to degeneration of its structures. Presently, a fully effective method of treatment has not been discovered, therefore preventative measures, especially those including a healthy diet and lifestyle, are highly important as the human body cannot synthesize these beneficial substances. This requires increasing public awareness concerning products with high nutritional value, which should be included in people's daily diet.
Publisher

Year
Volume
96
Pages
108-119
Physical description
Contributors
  • Department of Pathobiochemistry and Clinical Chemistry, Faculty of Pharmacy, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland
  • Department of Pathophysiology, Faculty of Pharmacy, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland
References
  • [1] McCusker MM., Durrani K., Payette MJ., Suchecki J., An eye on nutrition: The role of vitamins, essential fatty acids, and antioxidants in age-related macular degeneration, dry eye syndrome, and cataracts, Clinics in dermatology 34 (2016) 276-285
  • [2] Bartlett H., Eperjesi F., An ideal ocular nutritional supplement? Ophthalmic & Physiological Optics 24 (2004) 339-349
  • [3] Fu PP, Xia Q., Yin JJ, Cherng SH, Yan J., Mei N., Chen T., Boudreau MD, Howard PC, Wamer WG, Photodecomposition of vitamin A and photobiological implications for the skin, Photochemistry and photobiology 83 (2007) 409-424
  • [4] Gillissen A., Nowak D., Characterization of N-acetylcysteine and ambroxol in anti-oxidant therapy, Respiratory Medicine 92 (1998) 609-623
  • [5] Gillissen A, Jaworska M, Orth M., Nacystelyn and N-acetylcysteine augment cellular antioxidant defense in two distinctive ways, Respiratory Medicine 91 (1997) 159-168.
  • [6] Kim J., Clark RM., Park Y., Lee J., Fernandez ML, Lutein decreases oxidative stress and inflammation in liver and eyes of guinea pigs fed a hypercholesterolemic diet, Nutrition Research and Practice 6 (2012) 113-119
  • [7] Ma L., Lin XM, Effects of lutein and zeaxanthin on aspects of eye health, Journal of the Science of Food and Agriculture 90 (2010) 2-12
  • [8] Johnson EJ., Role of lutein and zeaxanthin in visual and cognitive function throughout the lifespan, Nutrition Reviews 72 (2014) 605-612
  • [9] Nowak JZ, Age-related macular degeneration (AMD): pathogenesis and therapy, Pharmacological Reports 58 (2006) 353-363
  • [10] Koushan K, Rusovici R, Li W, Ferguson LR, Chalam KV, The role of lutein in eye-related disease, Nutrients 22 (2013) 1823-1839
  • [11] Olmedilla B., Granado F., Blanco I & Vaquero M., Lutein, but not a-tocopherol, supplementatio improves Visual function in patients with age-related cataracts: A 2-y double blind, placebo-controlled study, Nutrition 19 (2003) 21-25
  • [12] Ambrożewicz E, Augustyniak A, Gęgotek A, Bielawska K, Skrzydlewska E., Black-currant protection against oxidative stress formation, Journal of Toxicology and Environmental Health 76 (2013) 1293-306
  • [13] Rong L., Tian W., Bao Z., Li Q., Changrui W., Qingshan L., Le M., Lutein and Zeaxanthin Supplementation and Association With Visual Function in Age-Related Macular Degeneration, Investigative Ophtalmology & Visual Science 2 (2013) 252-258
  • [14] Chhablani J., Roh YJ., Jobling AI., Fletcher EL., Lek JJ., Bansal P., Guymer R., Luttrull JK, Restorative retinal laser therapy: Present state and future directions, Survey of Ophthalmology 5 (2017)
  • [15] Hung H.C., Fruit and vegetable intake and risk of major chronic disease, JNCI: Journal of the National Cancer Institute 96 (2004) 1577-84
  • [16] Budzinskaia MV., Age-related macular degeneration, Vestnik oftalmologii 130 (2014) 56-60
  • [17] Kostrzewa B., Rojek A., Gabryś J., Karuga - Kuźniewska E., Staszuk A., Rybak Z., Age-related macular degeneration - disease of the 21st century, Acta Bio-Optica et Informatica Medica 21 (2015) 77-85
  • [18] Sandmann G., Carotenoids of biotechnological importance, Advances in Biochemical Engineering / Biotechnology 148 (2015) 449-467
  • [19] Khandhadia S., Cherry J., Lotery AJ, Age-related macular degeneration, Advances in Experimental Medicine and Biology 724 (2012)15-36
  • [20] Srivastava S., Srivastava AK., Lycopene; chemistry, biosynthesis, metabolism and degradation under various abiotic parameters, Journal of Food Science and Technology 52 (2015) 41-53
  • [21] Blasiak J., Petrovski G., Veréb Z., Facskó A., Kaarniranta K., Oxidative stress, hypoxia, and autophagy in the neovascular processes of age-related macular degeneration, BioMed research international 2014 (2014)
  • [22] Buschini E, Piras A, Nuzzi R et al., Age related macular degeneration and drusen: neuroinflammation in the retina, Progress in Neurobiology 95 (2011) 14-25
  • [23] Jiang Q., Natural forms of vitamin E: metabolism, antioxidant, and anti-inflammatory activities and their role in disease prevention and therapy, Free radicals biology & medicine 72 (2014) 76-90
  • [24] Hollyfield JG., Age-related macular degeneration: the molecular link between oxidative damage, tissue-specific inflammation and outer retinal disease, Investigative Ophthalmology & Visual Science 51 (2010) 1275-1281
  • [25] Landrum J., Bone R.A., Lutein, Zeaxanthin, and the Macular Pigment, Archives of Biochemistry and Biophysics 1 (2001) 28-40
  • [26] Sommerburg O., Keunen J., Bird A., Fruits and vegetables that are sources for lutein and zeaxanthin: the macular pigment in human eses, British Journal of Ophthalmology 82 (1998) 907-910
  • [27] Querques G., Souied EH., The role of omega-3 and micronutrients in age-related macular degeneration, Survey of Ophthalmology 59 (2014) 532-539
  • [28] Mathew C M., Ervin A-M., Tao J., Antioxidant vitamin supplementation for preventing and slowing the progression of age-related cataract, Cochrane Eyes and Vision Group 2 (2012)
  • [29] El-Raey M,, Ibrahim2 G., Eldahshan O., Lycopene and Lutein; A review for their Chemistry and Medicinal Uses, Journal of Pharmacognosy and Phytochemistry 1 (2013) 245-254
  • [30] Patel S., Mathan JJ., Vaghefi E., Braakhuis AJ., The effect of flavonoids on visual function in patients with glaucoma or ocular hypertension: a systematic review and meta-analysis, Graefe's Archive for Clinical and Experimental Ophthalmology 253 (2011) 1841-1850
  • [31] Panova IG., Stroeva OG., Ostrovskiĭ MA., Carotenoids of the human eye in prenatal and early postnatal development, Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 99 (2013) 1009-1022
  • [32] Xavier AA, Pérez-Gálvez A., Carotenoids as a Source of Antioxidants in the Diet, Sub-cellular biochemistry 79 (2016) 359-375
  • [33] Lima V.C., Rosen R.B., Farah M., Macular pigment In retinal health and diseas, International Journal of Retina and Vitreous 2 (2016)
  • [34] Lee S, Gura KM, Kim S, Arsenault DA, Bistrian BR, Puder M., Current clinical applications of omega-6 and omega-3 fatty acids, Nutrition in Clinical Practice 21 (2006) 323-341
  • [35] Krinsky NI, Landrum JT, Bone RA, Biologic mechanisms of the protective role of lutein and zeaxanthin in the Eye, Annual review of nutrition 23(2003) 171-201
  • [36] Bronwyn E., Sharon N., Gerald L., Victoria M. Flood, Lutein and Zeaxanthin—Food Sources, Bioavailability and Dietary Variety in Age-Related Macular Degeneration Protectio, Nutrients 9 (2017)
  • [37] Yu-Ping J., Lei S., He-Shui Y., Li-Peng L., Wei L., Hui D., Xin-Bo S., Li-Juan Z., The Pharmacological Effects of Lutein and Zeaxanthin on Visual Disorders and Cognition Diseases, Molecules 22 (2017)
  • [38] Schimel A.E., Abraham L. ,Cox D., Sene A., Kraus C., Dace D.S., Ercal N., Apte R.S., N-acetylcysteine amide (NACA) prevents retinal degeneration by up-regulating reduced glutathione production and reversing lipid peroxidation, The American Journal of Pathology 178 (2011) 2032-3043
  • [39] Lu L., Oveson B., Jo Y., Lauer T., Usui S, Komeima K, Xie B, Campochiaro P., Increased expression of glutathione peroxidase 4 strongly protects retina from oxidative damage, Antioxid Redox Signal 11 (2009) 715–724
  • [40] Grinberg L., Fibach E., Am J., Atlas D., N-acetylcysteine amide, a novel cell-permeating thiol, restores cellular glutathione and protects human red blood cells from oxidative stress, Free Radic Biology & Medicine 38 (2005) 136–145
  • [41] Schweigert FJ, Reimann J., Micronutrients and their relevance for the eye--function of lutein, zeaxanthin and omega-3 fatty acids, Klin Monbl Augenheilkd 228 (2011) 537-543
  • [42] Bowen P., Herbst-Espinosa S., Hussain E., Stacewicz-Sapuntzakis M., Esterification does not impair lutein bioavailability in humans. The Journal of Nutrition 132 (2002)
  • [43] Sherwin JC, Reacher MH, Dean WH, Ngondi J., Epidemiology of vitamin A deficiency and xerophthalmia in at-risk populations, Transactions of the Royal Society of Tropical Medicine and Hygiene 106 (2012) 205-2014
  • [44] Choy C., Benzie I., Cho P., Antioxidants in tears and plasma: Inter-relationships and effect of vitamin C Supplementation, Current Eye Research 27 (2003) 55-60
  • [45] Majumdar S., Srirangam R., Potential of the bioflavonoids in the prevention/treatment of ocular disorders, Journal of Pharmacy and Pharmacology 62 (2010) 951-965
Document Type
article
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.psjd-f11a82f3-8c47-459a-8df5-ce6ff46a8b91
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