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2017 | 12 | 63-72
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G6PD Activity in Malaria Infected Children in Owerri

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G6PD activity in malaria infected children in Owerri was studied. Blood samples were collected from fifty one (51) children hospitalized in Federal Medical Center (FMC) and analyzed using standard Medical Laboratory methods. Results revealed that out of the 51 children examined; 26 were male and 25 were females. 39 representing 76.47% of the total malaria infected children numbers were G6PD deficient while 12 representing 23.53% had their G6PD normal. Two different plasmodium species and their percentage occurrences were observed as follows; Plasmodium falciparum (78.43%) and Plasmodium malariae (21.57%). Result further showed that male children were more (P < 0.05) deficient than females with percentage levels of 61.53% and 38.47% respectively. Children between the ages of 49-60 months was observed to be more (P < 0.05) G6PD deficient with percentage 25.64%, while those between 0-12 months were least G6PD deficient with percentage of 8.3% (P < 0.05). There is therefore urgent need for public enlightenment on public health implications, need for proper hygiene as well as strategies for preventing and controlling mosquito bites which as a result curses malaria which has a high risk of degenerating Glucose-6-phosphate dehydrogenase (G6PD) deficiency in children.
Physical description
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