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In the paper, the preeliminary study of chitosan micro and nanospheres precipitation due to two
reverse emulsions (W/O) coalescence is described. The composition conditions, which must be
filled to obtain stable reverse emulsion is pointed out. Furthermore, the parameters of ultrasonic
emulsification and coalescence technique are presented and finally, morphological study of
obtained micro and nanospheres are discussed.
reverse emulsions (W/O) coalescence is described. The composition conditions, which must be
filled to obtain stable reverse emulsion is pointed out. Furthermore, the parameters of ultrasonic
emulsification and coalescence technique are presented and finally, morphological study of
obtained micro and nanospheres are discussed.
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13-20
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- Faculty of Process and Environmental Engineering, Lodz University of Technology, jacek.balcerzak@p.lodz.pl
author
- Institute of Biopolymers and Chemical Fibres
author
- Institute of Biopolymers and Chemical Fibres
References
- 1. Paul B K, Moulik S P; (2001) Uses and applications of microemulsions, Current Science 80, 990-1001.
- 2. Witek E, Kochanowski A, Pazdro M, Bortel E; (2006) Mikroemulsje jako źródło nanolateksów i nanoreaktorów, Polimery 51, 507-516.
- 3. Graf A, Jack K S, Whittaker A K, Hook S M, Rades T; (2008) Protein delivery using nanoparticles based on microemulsions with different structure-types, European Journal of Pharmaceutical Sciences 33, 434-444.
- 4. Grenha A; (2012) Chitosan nanoparticles: a survey of preparation methods, Journal of Drug Targeting 20, 291-300.
- 5. Shanmuganathan S, Shanumugasundaram N, Adhirajan N, Ramyaa Lakshmi T S, Babu M; (2008) Preparation and characterization of chitosan microspheres for doxycycline delivery, Carbohydrate Polymers 73, 201-211.
- 6. Biro E, Nemeth A Sz, Feczko T, Toth J, Sisak Cs, Gyenis J; (2009) Three-step experimental design to determine the effect of process parameters on the size of chitosan microspheres, Chemical Engineering and Processing 48, 771-779.
- 7. Wilson B, Samanta M K, Santhi K, Sampath Kumar K P, Ramasamy M, MPharm, Suresh B; (2010) Chitosan nanoparticles as a new delivery system for the anti-Alzheimer drug tacrine, Nanomedicine: Nanotechnology, Biology and Medicine 6, 144-152.
- 8. Anto S M, Kannan C, Sabari K K, Sathish K V, Suganeshwari M; (2011) Formulation of 5-fluorouracil chitosan loaded nanoparticles by emulsion droplet coalescence method for cancer therapy, International Journal of Pharmaceutical and Biological Archives 3, 926-931.
- 9. Du W, Niu S, Xu Y, Xu Z, Fan C; (2009) Antibacterial activity of chitosan tripolyphosphate nanoparticles loaded with various metal ions, Carbohydrate Polymers 75, 385-389.
- 10. Du Y, Ying X, Wang L, Zhai Y, Yuan H, Yu R, Hu F; (2010) Sustained release of ATP encapsulated in chitosan oligosaccharide nanoparticles, International Journal of Pharmaceutics 392, 164-169.
- 11. Landfester K; (2001) The generation of nanoparticles in miniemulsions, Advanced Materials 13, 765-768.
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article
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bwmeta1.element.psjd-eeb7bc05-9caf-482a-8f6a-426e9315b386