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2015 | 9 | 155-171
Article title

Synthesis, spectral studies and antimicrobial activities of some substituted (E)-1-benzylidene-2-(4-bromophenyl)hydrazines

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EN
Abstracts
EN
A series of nine number of (E)-1-benzylidene-2-(4-bromophenyl)hydrazine compounds have been synthesized by the condensation reaction of 4-bromo phenylhydrazine with varies m- and p- substituted benzaldehydes using acetic acid catalyst were refluxed for 4h with 20 mL of absolute ethanol. The yield of synthesized (E)-1-benzylidene-2-(4-bromophenyl)hydrazine compounds are more than 80%. The synthesized (E)-1-benzylidene-2-(4-bromophenyl)hydrazines have been characterized by UV, IR, 1H and 13C spectral data. These UV, IR and NMR spectral data have been correlated with varies Hammett substituted constant and Swain-Lupton F and R parameters using single and multi- regression analysis. From the results of statistical analysis, the effects of substituent have been studied. The antimicrobial activity of all the synthesized substituted (E)-1-benzylidene-2-(4-bromophenyl)hydrazines have been evaluated using Bayer-Kirby method.
Year
Volume
9
Pages
155-171
Physical description
References
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Document Type
article
Publication order reference
YADDA identifier
bwmeta1.element.psjd-ed7b4d81-8fac-4781-a484-1cf4e6269250
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