Research on the effects of planting season, density and spacing on the growth, development and yield components of honeysuckle (Lonicera japonica Thunb.)

• Authors: Doan Xuan Dinh , Pham Xuan Phong , Nguyen Hung Son , Nguyen Xuan Truong , Dinh Thanh Giang , Tran Thi Lien
• Languages of publication: EN

Abstracts

EN

Honeysuckle (Lonicera japonica Thunb.) has traditionally been used in medicine to treat mastitis, boils, itching, and allergic conditions. This study was conducted in Gia Lai to determine the appropriate planting season, density, and spacing to optimize the growth, development, yield, and quality of honeysuckle. May was identified as the optimal planting season, suitable for achieving high yield, vigorous growth, and good medicinal quality. The most suitable planting spacing for honeysuckle is 0.8 m × 0.8 m, corresponding to a density of 15,600 plants per hectare. The average yield of dried honeysuckle flowers ranges from 0.7 to 0.8 tons per hectare, while the yield of honeysuckle stems reaches 7.5 tons or more. The active compound content meets the standards specified in the Vietnamese Pharmacopoeia V (2017).

Keywords

EN

Honeysuckle; Lonicera japonica; density; planting season

Discipline

• MEDICAL_BIOLOGY: MEDICAL BIOLOGY

• Publisher: Scientific Publishing House „DARWIN”
• Journal: World News of Natural Sciences
• Year: 2026
• Volume: 64
• Pages: 232-245

Contributors

author

Doan Xuan Dinh

• Military Institue of Traditional Medicine, 442 Kim Giang Street, Dinh Cong Ward, Hanoi, Vietnam

author

Pham Xuan Phong

• Military Institue of Traditional Medicine, 442 Kim Giang Street, Dinh Cong Ward, Hanoi, Vietnam

author

Nguyen Hung Son

• Military Institue of Traditional Medicine, 442 Kim Giang Street, Dinh Cong Ward, Hanoi, Vietnam

author

Nguyen Xuan Truong

• National Institute of Medical Materials, 3B Quang Trung, Cua Nam Ward, Hanoi, Vietnam

author

Dinh Thanh Giang

• National Institute of Medical Materials, 3B Quang Trung, Cua Nam Ward, Hanoi, Vietnam

author

Tran Thi Lien

• National Institute of Medical Materials, 3B Quang Trung, Cua Nam Ward, Hanoi, Vietnam

References

• [1] Shang X., Pan H., Li M., Miao X., Ding H. Lonicera japonica Thunb.: ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine. Journal of Ethnopharmacology, 2011, 138(1): 1-21. https://doi.org/10.1016/j.jep.2011.08.016
• [2] Tang X., Liu X., Zhong J., Fang R. Potential Application of Lonicera japonica Extracts in Animal Production: From the Perspective of Intestinal Health. Front Microbiol. 2021, 12: 719877. https://doi.org/10.3389/fmicb.2021.719877
• [3] Hsu H.F., Hsiao P.C., Kuo T.C., Chiang S.T., Chen S.L., Chiou S.J., Ling X.H., Liang M.T., Cheng W.Y., Houng J.Y. Antioxidant and anti-inflammatory activities of Lonicera japonica Thunb. var. sempervillosa Hayata flower bud extracts prepared by water, ethanol and supercritical fluid extraction techniques. Ind Crops Prod. 2016, 89: 543-549. https://doi.org/10.1016/j.indcrop.2016.05.010
• [4] Li Y., Cai W., Weng X., Li Q., Wang Y., Chen Y., Zhang W., Yang Q., Guo Y., Zhu X., Wang H. Lonicerae Japonicae Flos and Lonicerae Flos: A Systematic Pharmacology Review. Evid Based Complement Alternat Med. 2015: 905063. doi: 10.1155/2015/905063
• [5] Zheng S., Liu S., Hou A., Wang S., Na Y., Hu Y., Jiang H., Yang L. Systematic review of Lonicerae Japonicae Flos: A significant food and traditional Chinese medicine. Front Pharmacol. 2022, 13: 1013992. https://doi.org/10.3389/fphar.2022.1013992
• [6] Phip, N. T., & Do, T. B. Effects of planting density and fertilization on growth, yield and loganin content of honeysuckle (Lonicera japonica Thunb.) in Thanh Tri, Hanoi. Vietnam Journal of Agricultural Sciences. 2018, 16(6), 563-570
• [7] Wang, L., Li, M., Yan, Y., Ao, M., Wu, G., & Yu, L.. Influence of flowering stage of Lonicera japonica Thunb. on volatile components and chlorogenic acid content. Journal of the Science of Food and Agriculture, (2009) 89(6), 953-959. https://doi.org/10.1002/jsfa.3533
• [8] Tran Thi Lien et al. Study on vegetative propagation of Lonicera japonica Thunb, in Gia Lai, Journal of Traditional Medicine and Pharmacy of the Military. 2025, Vol 1, 15/2025
• [9] Lin, L. M., Zhang, X. G., Zhu, J. J., Gao, H. M., Wang, Z. M., Wang, W. H., & Xiao, P. G. New triterpenoid saponins from the flowers and buds of Lonicera japonica Thunb. Planta Medica, (2008) 74(7), 790-795. https://doi.org/10.1055/s-2008-1074528
• [10] Borror D.J., C.A. Triplehorn and N.F. Johnson. An introduction to the study of insects. Sixth edition. Harcout College Publishers. Fort Worth Philadelphia San Diego New York Orlando Austin San Antonio Toronto Montreal London Sydney Tokyo. (1989) ISBN-10: 0-03-025397-7. Pages: 875 pp.
• [11] Liu, Z. X., Wang, X., & Li, W. Iridoid glycosides from the flower buds of Lonicera japonica and their biological activities. Natural Product Research, (2015) 29(23), 2213-2218. https://doi.org/10.1080/14786419.2014.1000895
• [12] Sun, C., Teng, Y., Liu, J., & Jin, Q. Metabolomics study of protective effects of Lonicera japonica extract during different growth stages. Phytochemistry, (2010) 71(7), 859-868. https://doi.org/10.1016/j.phytochem.2010.02.010
• [13] Zheng, S., Chen, J., Huang, Y., & Liu, Z. Quality assessment for the flower of Lonicera japonica Thunb. during flowering period by integrating GC-MS, UHPLC-HRMS and chemometrics. Journal of Pharmaceutical and Biomedical Analysis (2025) 239, 115875. https://doi.org/10.1016/j.jpba.2023.115875
• [14] Yuan, Y., Song, L., Li, M., Liu, G., & Chu, Y. Exploiting genes and functional diversity of chlorogenic acid and luteolin biosynthesis in Lonicera japonica. Plant Physiology and Biochemistry. (2014). 79, 91-100. https://doi.org/10.1016/j.plaphy.2014.03.009
• [15] Kakuda, R., Iijima, T., Yaoita, Y., & Kikuchi, M. Secoiridoid glycosides from the flower buds of Lonicera japonica Thunb. Chemical & Pharmaceutical Bulletin, (2000) 48(9), 1414-1417. https://doi.org/10.1248/cpb.48.1414
• [16] Wu Q., Zhao D., Leng Y., Chen C., Xiao K., Wu Z., Chen F. Identification of the Hypoglycemic Active Components of Lonicera japonica Thunb. and Lonicera hypoglauca Miq.by UPLC-Q-TOF-MS. Molecules. (2024), 29(20): 4848. https://doi.org/10.3390/molecules29204848
• [17] Tae J., Han S.W., Yoo J.Y., Kim J.A., Kang O.K., Baek O.S., Lim J.P., Kim D.K., Kim Y.H., Bae K.H., Lee Y.M. Anti-inflammatory effect of Lonicera japonica in proteinase-activated receptor 2-mediated paw edema. Clin Chim Acta. 2003, 330(1-2): 165-171. https://doi.org/10.1016/S0009-8981(03)00017-2
• [18] Xiong J., Li S., Wang W., Hong Y., Tang K., Luo Q. Screening and identification of the antibacterial bioactive compounds from Lonicera japonica leaves. Food Chemistry. Volume 138, Issue 1, 1 May 2013, Pages 327-333. https://doi.org/10.1016/j.foodchem.2012.10.127
• [19] Li, P., Wang, Y., Wang, X., & Liu, Y. Comparison of anti-inflammatory effects between Lonicerae japonicae flos and Lonicerae flos. Phytomedicine, (2016) 23(5), 534-540. https://doi.org/10.1016/j.phymed.2016.02.014
• [20] Zheng, J. Optimal harvesting stages for maximum phenylpropanoid accumulation in Lonicera japonica Thunb. Medicinal Plant Research, (2024) 14(3), 1-10
• [21] Yang, J., & Zhao, H. Seasonal variation of volatile oil constituents in Lonicera japonica Thunb. Chinese Journal of Natural Medicines, (2007) 5(4), 271-275

• Document Type: article