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2015 | 20 | 170-176
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In the present study, the results of viscosity measurements in dilute solutions of chitosan (Ch) with hyaluronic acid (HA) are presented. Chitosan is blended with hyaluronic acid in aqueous 0.1M CH3COOH/0.2M NaCl and 0.3M NaCl respectively, or with the addition of HEPES. Viscosity measurements of dilute polymer solution were carried out in an Ubbelohde capillary viscometer. The intrinsic viscosity, [], and the viscosity interaction parameters, bm, have been determined for the binary (solvent/polymer) and ternary (solvent/polymer A/polymer B) systems. The homogeneity and morphology of chitosan blends were ascertained from the tapping-mode atomic force microscopy. The surface roughness of chitosan, hyaluronic acid and Ch/HA blended films was altered by mixing. The obtained results suggested that there was existence of the strong interactions between chitosan and hyaluronic acid.
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  • Faculty of Chemistry, Nicolaus Copernicus University, ul. Gagarin 7, 87-100 Toruń, Poland
  • Faculty of Chemistry, Nicolaus Copernicus University, ul. Gagarin 7, 87-100 Toruń, Poland
  • Faculty of Chemistry, Nicolaus Copernicus University, ul. Gagarin 7, 87-100 Toruń, Poland
  • 1. Sionkowska A; (2011) Current research on the blends of natural and synthetic polymers: Review. Prog Polym Sci 36, 1254-1276. DOI: 10.1016/j.progpolymsci.2011.05.003
  • 2. Lewandowska K; (2009) Miscibility and thermal stability of poly(vinyl alcohol)/chitosan mixtures. Thermochimica Acta 493, 42-48.
  • 3. Sionkowska A, Lewandowska K, Płanecka A; (2014) Miscibility and physical properties of chitosan and silk fibroin mixtures. J Mol Liq 198, 354-357. DOI: 10.1016/j.molliq.2014.07.033
  • 4. Liu H, Yin Y, Yao K, Ma D, Cui L, Cao Y; (2004) Influence of the concentration of hyaluronic acid on the properties and biocompatibility of Cs-Gel-HA membranes. Biomaterials 25, 3523-3530.
  • 5. Schanté CE, Zuber G, Herlin C, Vandamme TE; (2011) Chemical modifications of hyaluronic acid for the a broad range of biomedical applications. Carbohydr Polym 85, 469-489. DOI: 10.1016/j.carbp11.03.019
  • 6. Krigbaum WR, Wall FT; (1950) Viscosities of binary polymeric mixtures. J Polym Sci 5, 505-514. DOI: 10.1002/pol.1950.120050408
  • 7. Garcia R, Melad O, Gómez, CM, Figueruelo JE, Campos A; (1999) Viscometric study on the compatibility of polymer-polymer mixtures in solution. Eur Polym J 35, 47-55. DOI: 10.1016/S0014-3057(98)00106-2
  • 8. Catsiff EH, Hewett WA; (1962) The interaction of two dissimilar polymers in solution. J Appl Polym Sci 6, S30-S32. DOI: 10.1002/app.1962.070062322
  • 9. Chee KK; (1990) Determination of polymer-polymer miscibility by viscometry. Eur Polym J 26, 423-426. DOI: 10.1016/0014-3057(91)90199-X
  • 10. Lewandowska K; (2005) The miscibility of poly(vinyl alcohol)/poly(Nvinylpyrrolidone) blends investigated in dilute solutions and solids. Eur Polym J 41, 55-64. DOI: 10.1016/j.eurpolymj.2004.08.016
  • 11. Lewandowska K; (2011) Viscometric studies of microcrystalline chitosan/poly(vinyl alcohol) mixtures. Progress on Chemistry and Application of Chitin and Its Derivatives, XVI, 43-47.
  • 12. Lewandowska K; (2013) Viscometric studies in dilute solution mixtures of chitosan and microcrystalline chitosan with poly(vinyl alcohol). J Solution Chem 42, 1654-1662. DOI: 10.1007/s10953-013-0053-3
  • 13. Lewandowska K; (2012) Surface studies of microcrystalline chitosan/poly(vinyl alcohol) mixtures. Appl Surf Sci 263, 115-123.
  • 14. Lewandowska K, Sionkowska A, Kaczmarek B, Furtos G; (2014) Characterization of chitosan composites with various clays. Int J Biol Macromol 65, 534-541. DOI: 10.1016/j.ijbiomac.2014.01.069
  • 15. Lewandowska K; (2014) Characterization of thin chitosan/polyacrylamide blend films. Mol Cryst Liq Cryst 590, 186-192.
  • 16. Huggins MH; (1942) The viscosity of dilute solutions of long-chain molecules. IV. Dependence on concentration. J Am Chem Soc 64, 2716-2718. DOI: 0.1021/ja01263a055
  • 17. Bohdanecký M, Kovář I; (1982) Viscosity of Polymer Solution. Vol 2 In: Jenkins AD (ed) Elsevier Science, Amsterdam.
  • 18. Lewandowska K, Sionkowska A, Krasińska K; (2014) Viscometric studies of chitosan/polyacrylamide mixtures. Progress in Chemistry and Application of Chitin and Its Derivatives, XIX, 73-78.
  • 19. Pingping Z, Haiyang Y, Shiqiang W; (1998) Viscosity behavior of poly-e-caprolactone (PCL)/poly(vinyl chloride) (PVC) blends in various solvents. Eur Polym Sci 34, 91–94. DOI: 10.1016/S0014-3057(97)00075-X
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