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2017 | 22 | 1 | 17-22

Article title

Fenotypy astmy oskrzelowej w starszym wieku

Content

Title variants

EN
Phenotypes of asthma in the elderly

Languages of publication

PL EN

Abstracts

PL
Astma występuje z podobną częstością w każdej grupie wiekowej. U osób starszych astma jest zbyt rzadko rozpoznawana lub błędnie rozpoznawana i niedostatecznie leczona. Leczenie starszych pacjentów jest często utrudnione przez współchorobowość, częstsze ograniczenia funkcji poznawczych, większe obciążenie chorobą oraz zmiany patofizjologiczne związane z wiekiem. W dobie medycyny spersonalizowanej lekarze wykorzystują podział fenotypowy dla ułatwienia diagnozowania i doboru właściwego sposobu leczenia. Często stosuje się podziały w zależności od aktualnego wieku pacjenta (astma dziecięca, dorosłych i osób starszych) lub wieku wystąpienia choroby (astma o wczesnym i późnym początku). Wśród osób starszych spotyka się podział związany z dominującymi komórkami zapalnymi, wyróżnia się astmę eozynofilową i neutrofilową. Często uwzględnia się problem współwystępowania otyłości i zaburzeń neuropsychiatrycznych u starszych pacjentów z astmą. W artykule przedstawiono najczęstsze metody klasyfikacji pacjentów z astmą oskrzelową, w tym metodę klastrową. Przedstawiono najważniejsze publikacje i opisane w nich cechy charakterystyczne dla każdej grupy
EN
Asthma has similar prevalence in all age groups. In elderly patients asthma is often undiagnosed, wrongly diagnosed and/or undertreated. Treatment of elderly patients is troublesome because of comorbidities, more frequent cognitive limitations, greater burden of disease and pathophysiological process of aging. In the age of personalized medicine physicians use phenotypes to improve diagnostics and develop individual treatment. In the paper we discuss phenotypes of asthma in the elderly patients. Asthma can be differentiated to age (childhood asthma, adult asthma and elderly asthma) or the age of asthma onset (early and late asthma onset). Also, there is a classification based on the dominant inflammatory cells (eosinophilic asthma, neutrophilic asthma). Other phenotypes are connected with different comorbidities (obesity asthma phenotype, COPD, neuropsychiatric disorders). We describe classification methods including cluster analysis and point out the most important similarities within the groups.

Discipline

Year

Volume

22

Issue

1

Pages

17-22

Physical description

Contributors

  • Klinika Immunologii, Reumatologii i Alergii Katedry Immunologii Klinicznej i Mikrobiologii Uniwersytetu Medycznego w Łodzi
  • Klinika Immunologii, Reumatologii i Alergii Katedry Immunologii Klinicznej i Mikrobiologii Uniwersytetu Medycznego w Łodzi

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Document Type

article

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.psjd-e9e01934-840d-466b-a148-4882582307ba
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