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2018 | 8 | 2 | 48-53
Article title

Current diagnosis and treatment of Nelson’s syndrome

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EN
Abstracts
EN
Nelson’s syndrome is a rare condition of enlarging pituitary mass lesion producing ACTH that can develop after total bilateral adrenalectomy (TBA) in patients with Cushing’s disease. It is characterized by hyperpigmentation of the skin and mucous membranes and elevated plasma levels of ACTH. In this clinical review, the diagnosis and treatment strategies of patients with Nelson’s syndrome including surgery, radiation, and pharmacotherapy are presented.
Discipline
Publisher

Journal
Year
Volume
8
Issue
2
Pages
48-53
Physical description
Contributors
  • University Hospital in Cracow
  • Department of Neurosurgery, Central Teaching Hospital of the Ministry of Defence, Military Institute of Medicine
  • Department of Gastroenterology, Endocrinology and Internal Diseases, Central Teaching Hospital of the Ministry of Defence, Military Institute of Medicine
author
  • Department of Gastroenterology, Endocrinology and Internal Diseases, Central Teaching Hospital of the Ministry of Defence, Military Institute of Medicine
  • Department of Gastroenterology, Endocrinology and Internal Diseases, Central Teaching Hospital of the Ministry of Defence, Military Institute of Medicine, pwitek@wim.mil.pl
References
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  • 4. Nelson DHJW, Meakin JB, Dealy JB Jr et al. ACTH – producing tumor of the pituitary gland. N Engl J Med 1958; 259: 161-164.
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  • 20. Katznelson L. Sustained improvements in plasma ACTH and clinical status in a patient with Nelson’s syndrome treated with pasireotide LAR, a multireceptor somatostatin analog. J Clin Endocrinol Metab 2013; 98(5): 1803-1807.
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  • 31. Koulouri O, Steuwe A, Gillett D et al. A role for C-methionine PET imaging in ACTH-dependent Cushing’s syndrome. Eur J Endocrinol 2015; 173: M107-M120.
Document Type
article
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bwmeta1.element.psjd-deb54cbf-ecbb-47a3-b943-b18273d664e8
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