PL EN


Preferences help
enabled [disable] Abstract
Number of results
Journal
2014 | 4 | 3 | A100-107
Article title

Remote consequences of polychemical and radiation therapy: cardiac valve disease complicated by infective endocarditis. Diagnostic and management problems

Content
Title variants
Languages of publication
EN
Abstracts
EN
One of the quite frequent long-term effects of radiation therapy of malignant tumors, such as breast cancer and Hodgkin’s lymphoma primarily, when the irradiation of the mediastinum is performed, is the development of radiation-induced valvular disease. It is noted that the clinical manifestation of valve dysfunction can typically arise approximately 5 years after a course of anticancer radiotherapy. Thereafter in these patients increases the risk of infective endocarditis. However, in therapeutic and oncological clinical practice the difficulty of identifying and making the differential diagnosis of endocarditis in patients with “cancer” history is still quite common. At the moment cases of infective endocarditis after polychemotherapy and radiation therapy are not widely covered for cardiologists and internists in the medical literature. In addition before starting specific treatment due to the possible threat of infectious complications, including endocarditis, in oncology guidelines it is recommended to patients to make a thorough oral cavity sanitation, while the internists are little aware of this need, both at the stage of antitumor therapy and at late period. Today, with the increasing number of patients who are healed or achieved long-term remission after the anticancer treatment, including elderly people, it is necessary to raise the awareness among internists about occurrence options of comorbid disease in these group.
Discipline
Publisher

Journal
Year
Volume
4
Issue
3
Pages
A100-107
Physical description
Contributors
  • St. Petersburg Hospital of Russian Academy of Sciences; Medical Director of St. Petersburg Hospital of Russian Academy of Sciences; Chief of Cardiology Department of Russian Academy of Sciences
  • St. Petersburg Hospital of Russian Academy of Sciences
  • St. Petersburg Hospital of Russian Academy of Sciences
  • St. Petersburg Hospital of Russian Academy of Sciences
  • Federal Almazov Heart, Lung and Endocrinology Center
References
  • Frielander AH, Sung EC, Child JS. Radiation-induced heart disease after Hodgkin’s disease and breast cancer treatment: dental implications. J Am Dent Assoc. 2003; 134(12): 1615-20.
  • Byrd BF, Mendes LA. Cardiac complications of mediastinal radiotherapy: the other side of the coin. J Am Coll Cardiol 2003; 42(4): 750-751.
  • Yusuf SW, Sami S, Daher IN. Radiation-Induced Heart Disease: A Clinical Update. Cardiology Research and Practice 2011 [online: http://dx.doi.org/10.4061/2011/317659].
  • Brand M.D, Abadi CA, Aurigemma GP. Radiation-associated valvular heart disease in Hodgkin‘s disease is associated with characteristic thickening and fibrosis of the aortic-mitral curtain. Journal of Heart Valve Disease 2001; 10(5): 681-685.
  • Tamura A, Takahara Y, Mogi K, Katsumata M. Radiation-induced valvular disease is the logical consequence of irradiation. General Thoracic and Cardiovascular Surgery 2007; 55(2): 53-56.
  • Hong CH, Napeńas JJ, Hodgson BD. A systematic review of dental disease in patients undergoing cancer therapy. Support Care Cancer 2010; 18(8): 1007-21.
  • Ballyuzek MF, Stepanov BP. Aims and opportunities of therapeutic rehabilitation of oncology patients. Clinacal Medicine/Klinicheskaja medizina 2013; 9: 52-56.
  • Wong DD, Ramaseshan G, Mendelson RM. Comparison of the Wells and Revised Geneva Scores for the diagnosis of pulmonary embolism: an Australian experience. Internal Medicine Journal 2011; 41(3): 258-263.
Document Type
report
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.psjd-dc198f8d-cfe3-4b5e-9117-1509ff9fd4ae
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.