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2017 | 74 | 238-250
Article title

Antimicrobal susceptibility pattern of methicillin resistant Staphylococcus aureus isolatetd from pediatric clinical samples at Webuye District Hospital

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EN
Methicillin Resistant Staphylococcus aureus (MRSA) is an important nosocomial pathogen causing a significant mortality and morbidity. The main objective of the study was to establish antibiotic susceptibility pattern MRSA isolated from pediatrics clinical samples at Webuye District Hospital. A total of 96 clinical samples that include blood, abscess, ear swabs, and urine and wound/pus swabs were collected by simple random techniques. These samples were cultured onto Blood agar and MacConkey agar respectively and incubated at 37oC for 24 hours. In the result 83 (86.5%) clinical samples had pure colonies of S. aureus which were identified morphologically and biochemically by standard laboratory procedures using Bergey’s Manual of Clinical Microbiology. All confirmed positive isolates were screened for MRSA whereby 18 (21.7%) were MRSA and these were subjected to susceptibility testing to common antibiotics by modified Kirby-Bauer disc diffusion method. The susceptibility was interpreted according to National Clinical laboratory Standard guidelines. From the study the prevalence of MRSA was 18 (21.7%) with the highest obtained in the wound/pus swab. Almost all MRSA was resistant to penicillin (92.8%) and cephalexin (96.6%) and amoxicillin (91%). The most effective antibiotics against the of MRSA strain were vancomycin (98.97%), ciprofloxacin (88.4%) and gentamycin (83.06%). Vancomycin was the most effective drug showed the largest inhibition zone.
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74
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238-250
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References
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article
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bwmeta1.element.psjd-d9c983d7-6d60-4bc3-b948-b53e3199657c
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