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Journal
2016 | 3 | 2 | 82-86
Article title

Zastosowanie niesteroidowych leków przeciwzapalnych w terapii wybranych patologii narządu wzroku

Content
Title variants
EN
The use of nonsteroidal anti-inflammatory drugs in therapy of selected pathologies of the eye
Languages of publication
PL
Abstracts
EN
Nonsteroidal anti-inflammatory drugs are widely used in ophthalmology. This drugs have anti-inflammatory and analgesic activity by inhibiting two cyclooxygenase (COX) isoforms: COX-1 and COX-2. Therapeutic indications involve reduction of pain and photophobia after refractive surgery, prevention and treatment of inflammation and cystoid macular edema after cataract surgery, inhibition of intraoperative miosis during cataract surgery, treatment of allergic conjunctivitis. Lately they are also used for treatment of the diseases of the posterior part of the eye – diabetic retinopathy and age-related macular degeneration. This article shows the use of NSAIDs in selected eye diseases.
PL
Niesteroidowe leki przeciwzapalne są szeroko stosowane w praktyce okulistycznej. Leki te wykazują działanie przeciwzapalne i przeciwbólowe poprzez hamowanie aktywności izoenzymów cyklooksygenazy (COX-1, COX-2). Wykorzystuje się je w łagodzeniu dolegliwości bólowych, światłowstrętu po zabiegach laserowej korekcji wad wzroku, w celu ograniczenia stanu zapalnego, zapobieżenia zwężaniu źrenicy i torbielowatego obrzęku plamki po zabiegach usunięcia zaćmy, a także w alergicznym zapaleniu spojówek. W ostatnim czasie znalazły również zastosowanie w leczeniu chorób tylnego odcinka oka – w retinopatii cukrzycowej i zwyrodnieniu plamki związanym z wiekiem. W artykule przedstawiono wykorzystanie NLPZ w wybranych jednostkach chorobowych narządu wzroku.
Discipline
Publisher
Journal
Year
Volume
3
Issue
2
Pages
82-86
Physical description
References
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  • 2. Kim SJ, Flach AJ, Jampol LM. Nonsteroidal anti-inflammatory drugs in ophthalmology. Surv Ophthalmol 2010; 55: 108-133.
  • 3. Jones B, Neville MW. Nepafenac: an ophthalmic nonsteroidal antiinflammatory drug for pain after cataract surgery. Ann Pharmacother 2013; 47: 892-896.
  • 4. Guo S, Patel S, Baumrind B, et al. Management of pseudophakic cystoid macular edema. Surv Ophthalmol 2015; 60: 123-137.
  • 5. O’Brien TP. Emerging guidelines for use of NSAID therapy to optimize cataract surgery patient care. Curr Med Res Opin 2005; 21: 1131- -1137.
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  • 9. Colin J, Paquette B. Comparison of the analgesic efficacy of nepafenac ophthalmic suspension compared with diclofenac ophthalmic solution for ocular pain and photophobia after excimer laser surgery: a phase II, randomized, double-masked trial. Clin Ther 2006; 28: 527-536.
  • 10. Durrie DS, Kennard MG, Boghossian AJ. Effects of nonsteroidal ophthalmic drops on epithelial healing and pain in patients undergoing bilateral photorefractive keratectomy (PRK). Adv Ther 2007; 24(6): 1278-1285.
  • 11. Gomi F, Sawa M, Tsujikawa M, Nishida K. Topical bromfenac as an adjunctive treatment with intravitreal ranibizumab for exudative age-related macular degeneration. Retina 2012; 32: 1804-1810.
  • 12. Sahoo S, Baruna A, Myint KT, et al. Topical non-steroidal anti-inflammatory agents for diabetic cystoid macular oedema (review). The Cochrane Library 2015; Issue 2: 1-17.
  • 13. Ke TL, Graff G, Spellman JM, Yanni JM. Nepafenac, a unique nonsteroidal prodrug with potential utility in the treatment of trauma- -induced ocular inflammation. II. In vitro band permeation of external ocular barriers. Inflammation 2000; 24(4): 371-384.
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article
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YADDA identifier
bwmeta1.element.psjd-d6e0d75c-8195-48b1-b98c-275d21976ea6
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