Alergia na roztocza kurzu domowego i krewetki – co wiemy obecnie?

• Authors: Natalia Ukleja-Sokołowska , Łukasz Sokołowski , Zbigniew Bartuzi

Title variants

EN

Allergy to house dust mites and shrimp - what do we know now?

• Languages of publication: PL EN

Abstracts

PL

Alergia na roztocza kurzu domowego jest najczęstszą przyczyną ca- łorocznego alergicznego nieżytu nosa w Polsce. Krewetki natomiast stanowią bogate źródło białek, które mogą stanowić powód nadwraż- liwości. Wiadomo, że tropomiozyna roztoczy kurzu domowego ma budowę sekwencyjną homologiczną do tropomiozyny krewetek. Opisano do tej pory kilkadziesiąt alergenów roztoczy. Ponad 97% pacjentów uczulonych jest na białka roztoczy będące proteazą cysteinową (Der p 1, Der f 1) oraz należących do rodziny NPC2 (Der p 2, Der f 2). Pomimo to liczba dostępnych komponent stale wzrasta, a interpretacja wyniku niejednokrotnie może sprawiać trudności. W pracy scharakteryzowano opisane do tej pory alergeny roztoczy kurzu domowego i krewetek. Przybliżono także dostępne możliwości w diagnostyce uczulenia na te alergeny.

EN

Allergy to house dust mites is the most common cause of perennial allergic rhinitis in Poland. Shrimps, on the other hand, are a rich source of proteins that may be the cause of hypersensitivity. It is known that tropomyosin of house dust mite is highly homologous to the tropomyosin of shrimps. Several dozen mite allergens have been described so far. Over 97% of patients are sensitized to cysteine protease (Der p 1, Der f 1) and members of the NPC2 protein family (Der p 2, Der f 2). Due to relatively small number of patients allergic to other allergen components of house dust mite, the number of commercially available allergen components of house dust mite is still limited. Nevertheless, the number of commercially available allergen components of house dust mite is constantly increasing, and the interpretation of the result can often cause difficulties. In this article we present house dust mite and shrimp allergens that were described so far. The current diagnostic possibilities in sensitization to these allergens are also presented.

Keywords

EN

alergia; alergiakrzyżowa; diagnostyka oparta o komponenty alergenowe; krewetki; roztocza kurzu domowego

Discipline

• MEDICINE: MEDICINE

• Publisher: Oficyna Wydawnicza Mediton
• Journal: Alergia Astma Immunologia - przegląd kliniczny
• Year: 2018
• Volume: 23
• Issue: 4
• Pages: 221-227

Contributors

author

Natalia Ukleja-Sokołowska

• Katedra i Klinika Alergologii, Immunologii Klinicznej i Chorób Wewnętrznych, Collegium Medicum im. L. Rydygiera w Bydgoszczy, UMK

author

Łukasz Sokołowski

• Katedra Higieny, Epidemiologii i Ergonomii, Zakład Ergonomii i Fizjologii Wysiłku Fizycznego, Collegium Medicum im. L. Rydygiera w Bydgoszczy, UMK

author

Zbigniew Bartuzi

• Katedra i Klinika Alergologii, Immunologii Klinicznej i Chorób Wewnętrznych, Collegium Medicum im. L. Rydygiera w Bydgoszczy, UMK

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• Document Type: article