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Journal
2020 | 10 | 1 | 23-26
Article title

Efficacy of trifluridine/tipiracil as IV line chemotherapy in a young woman with metastatic colorectal cancer. A case report

Content
Title variants
Languages of publication
EN
Abstracts
EN
Colorectal cancer is the most common gastrointestinal malignancy and the third most frequently diagnosed cancer worldwide. Trifluridine/tipiracil represents an approved option for the treatment of advanced metastatic colorectal cancer in patients who are refractory, or are not considered candidates for currently available therapies. We present a case of a young woman with refractory metastatic colorectal cancer treated with this agent as the IV line of chemotherapy in which remarkable prolongation of progression free survival time was observed.
Discipline
Publisher

Journal
Year
Volume
10
Issue
1
Pages
23-26
Physical description
Contributors
  • Department of Oncology and Hematology, Beskid Oncology Centre – John Paul II Memorial City Hospital in Bielsko-Biala
References
  • 1. Magalhaes B, Peleteiro B, Lunet N. Dietary patterns and colorectal cancer: systematic review and meta-analysis. Eur J Cancer Prev. 2012; 21: 15-23.
  • 2. Ferlay J, Soerjomataram I, Dikshit R et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015; 136: E359-86.
  • 3. Van Cutsem E, Cervantes A, Adam R et al. ESMO consensus guidelines for the management of patients with metastatic colorectal cancer. Ann Oncol. 2016; 27(8): 1386-422.
  • 4. Salvatore L, Rossini D, Moretto R et al. TAS-102 for the treatment of metastatic colorectal cancer. Expert Rev Anticancer Ther. 2015; 15(11): 1283-92.
  • 5. Lenz HJ, Stintzing S, Loupakis F. TAS-102, a novel antitumor agent: a review of the mechanism of action. Cancer Treatment Rev. 2015; 41: 777-83.
  • 6. Burness CB, Duggan ST. Trifluridine/tipiracil: a review in metastatic colorectal cancer. Drugs. 2016; 76: 1393-402.
  • 7. Mayer R, Van Cutsem E, Falcone A et al.; RECOURSE Study Group. Randomized trial of TAS-102 for refractory metastatic colorectal cancer. N Engl J Med. 2015;372:1909-19.
  • 8. European Medicines Agency. European public assessment report (EPAR) for Lonsurf. 2016. http://www.ema.europa.eu.
Document Type
article
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.psjd-d3954e19-76ab-4ecb-a2b0-5fe9e480edf1
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