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2016 | 70 | 127–132
Article title

Prognostic relevance of hyponatremia after first-ever ischemic stroke

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PL
Znaczenie hiponatremii u chorych z pierwszym w życiu udarem niedokrwiennym mózgu
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Abstracts
EN
INTRODUCTION: Hyponatremia is examined as a prognostic factor after first-time ischemic cerebrovascular incident (CVA, ischemic stroke). MATERIALS AND METHODS: 677 patients were analyzed after first-time ischemic stroke and divided into two groups according to sodium concentration: ≤ 135 mmol/L and > 135 mmol/L. RESULTS: For patients with sodium levels ≤ 135 mmol/L, the median National Institutes of Health Stroke Scale (NIHSS) score was 5 points, the median Modified Rankin Scale (mRS) was 4 points, and the mortality within 1 month of ischemic stroke was 10.5%. Patients with sodium levels > 135 mmol/L: NIHSS 3 points, mRS 2 points and mortality 1 month after ischemic stroke 3.4%. Mortality within 1 month of ischemic stroke in hyponatremic patients: women 16.4%, men 3.5% (p = 0.0194). Greater disability was seen in eunatremic women as assessed by increased mRS scores (p = 0.005). CONCLUSIONS: Hyponatremia is associated with a worsened heath status in patients in the acute and sub-acute phase after first-time ischemic stroke and is associated with increased mortality within 1 month after the stroke. Women with hyponatremia were characterized by greater mortality within one month after their first-ever ischemic stroke. In women with normal serum sodium at the time of stroke, a higher degree of disability was observed as assessed by increased mRS scores compared to men.
PL
WSTĘP: Hiponatremię uważa się za czynnik ryzyka udaru mózgu. MATERIAŁ I METODY: Przeanalizowano 677 chorych z pierwszym w życiu udarem niedokrwiennym mózgu, których podzielono w zależności od stężenia sodu w surowicy na dwie podgrupy: ≤ 135 mmol/l i > 135 mmol/l. WYNIKI: U chorych ze stężeniem sodu ≤ 135 mmol/l mediana w skali NIHSS wyniosła 5 pkt, mediana oceny stopnia inwalidztwa według skali mRankin wynosiła 4 pkt, a śmiertelność w okresie jednego miesiąca od zachorowania wynosiła 10,5%, w grupie ze stężeniem sodu > 135 mmol/l stwierdzono odpowiednio: 3 pkt, 2 pkt, i 3,4%. U chorych z hiponatremią śmiertelność w ciągu miesiąca od zachorowania wynosiła u kobiet 16,4%, u mężczyzn 3,5% (p = 0,0194). U kobiet z prawidłową natremią obserwowano większy stopień inwalidztwa w skali mRankin (p = 0,005). WNIOSKI: Hiponatremia ma niekorzystny wpływ na stan pacjentów zarówno w ostrej, jak i podostrej fazie udaru oraz wiąże się ze zwiększoną śmiertelnością miesięczną od zachorowania. Kobiety z hiponatremią cechowała większa śmiertelność w ciągu jednego miesiąca po przebytym pierwszym w życiu udarze niedokrwiennym. U kobiet z prawidłowym stężeniem sodu w czasie pierwszego w życiu udaru niedokrwiennego stwierdzano wyższy stopień inwalidztwa ocenianego w skali mRankin w porównaniu z mężczyznami.
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Year
Volume
70
Pages
127–132
Physical description
Contributors
  • Department of Neurology, Medical University of Silesia in Katowice, Hospital No. 7, Professor Leszek Giec Upper Silesian Medical Centre, Katowice, Poland
  • Department of Neurology, Medical University of Silesia in Katowice, Hospital No. 7, Professor Leszek Giec Upper Silesian Medical Centre, Katowice, Poland, Faculty of Physiotherapy – Institute of Rehabilitation Medicine, School of Health Sciences in Katowice, Medical University of Silesia in Katowice, Poland
  • Department of Internal Medicine and Metabolic Disease, School of Health Sciences in Katowice, Medical University of Silesia in Katowice, ul. Ziołowa 45-47, 40-635 Katowice, Poland, tel. 32 359 82 23, holomed@gmail.com
  • Department of Internal Medicine and Metabolic Disease, School of Health Sciences in Katowice, Medical University of Silesia in Katowice, Poland
  • Department of Geriatrics, School of Health Sciences in Katowice, Medical University of Silesia in Katowice, Poland
author
  • Department of Internal Medicine and Metabolic Disease, School of Health Sciences in Katowice, Medical University of Silesia in Katowice, Poland
References
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article
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bwmeta1.element.psjd-ce1d78b9-8a99-44b9-b8fd-619191dc789d
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