Synthesis, sprectral analysis and antimicrobial activity of 1,2,3-triazole and arylamide derivatives using 4-aminoantipyrine nucleus

• Authors: Priyanka Pankhaniya , Nikhil P. Savaniya , Dipak M. Purohit
• Languages of publication: EN

Abstracts

EN

Pyrazole derivatives shows remarkable antibacterial activity, antifungal activity, anti-oxidant activity, anti-inflammatory activity, anticancer activity etc. In view of getting to synthesize 2-{4’-[1’,5’-Dimethyl-3’-oxo-2’-phenyl-pyrazol-4’-yl]aminomethyl-1H-1,2,3-triazol-1-yl}-N-arylethanamide derivatives (8a-8j) and 2-[(1’,5’-dimethyl-3’-oxo-2’-phenyl-pyrazol-4’-yl)amino]-N-arylethanamide derivatives (9a-9j). The structures of the compounds were analyzed by IR, 1H NMR, mass spectral data and TLC. The synthesized compounds were evaluated their antimicrobial activity with Gram-positive, Gram-negative bacteria and fungi.

Keywords

EN

1-2-3-traizole; 4-aminoantipyrine; Anti-fungal Activity; Antibacterial Activity; Arylamide; Click chemistry; CuAAC

Discipline

• BIOCHEMISTRY: BIOCHEMISTRY

• Publisher: Scientific Publishing House „DARWIN”
• Journal: World News of Natural Sciences
• Year: 2024
• Volume: 54
• Pages: 159-169

Contributors

author

Priyanka Pankhaniya

• Department of Chemistry, Shree M. & N. Virani Science College, Rajkot - 360005, India

author

Nikhil P. Savaniya

• Department of Chemistry, Government Science College, Ahwa, Dist. Dang - 394710, India

author

Dipak M. Purohit

• Department of Chemistry, Shree M. & N. Virani Science College, Rajkot - 360005, India

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• Document Type: article