Primary cutaneous B-cell lymphoma located on the face and hard palate

• Authors: Piotr Brzeziński , Anca Chiriac , Radu Budurca , Anca E. Chiriac , Tudor Pinteala , Luminita Ivan , Liliana Foia
• Languages of publication: EN

Abstracts

EN

Introduction: Primary cutaneous B-cell lymphomas represent primary cutaneous lymphomas. The World Health Organization-European Organization for Research and Treatment of Cancer defines primary cutaneous B-cell limphomas as malignant lymphomas that are confined to the skin at presentation after complete staging procedures. Case report: We report a case of a woman with a cutaneous nodular B-cell lymphoma of the face, with very slow evolution that could easily be misdiagnosed. The patient had two non-ulcerated nodules on the left part of the face. A histological examination on both pieces following surgical excision showed a diffuse infiltrate of atypical B cells. The patient was subsequently directed to the Oncology Department for further investigation, but she died 24 hours afterwards due to one of the acute possible complications of the disease: pulmonary embolism. Conclusion: Cutaneous B-cell lymphoma is an unusual and rare skin neoplasm with a great range of clinical presentations and this is an alarm sign for apparent common skin lesion.

Keywords

EN

B-cell lymphoma; face and hard palate lymphoma; non-Hodgkin lymphoma

Discipline

• MEDICINE: MEDICINE

• Journal: OncoReview
• Year: 2014
• Volume: 4
• Issue: 3
• Pages: A113-116

Contributors

author

Piotr Brzeziński

• Military Ambulatory, 6th Military Support Unit, Ustka, Poland,

author

Anca Chiriac

• Apollonia University Iasi, Dermato-Physiology Department, Iasi, Romania

author

Radu Budurca

• Department of Surgery, University of Medicine and Pharmacy “Gr. T. Popa”, Iasi, Romania

author

Anca E. Chiriac

• University of Medicine and Pharmacy “Gr. T. Popa”, Iasi, Romania

author

Tudor Pinteala

• University of Medicine and Pharmacy “Gr. T. Popa”, Iasi, Romania

author

Luminita Ivan

• Department of Pathology, CF Hospital, Iasi, Romania

author

Liliana Foia

• Department of Biochemistry, University of Medicine and Pharmacy “Gr. T. Popa”, Iasi, Romania

References

• Thomas BR, Whittaker S. A practical approach to accurate classification and staging of mycosis fungoides and Sézary syndrome. Skin Therapy Lett 2012; 17: 5-9.
• Willemze R, Jaffe ES, Burg G et al. WHO-EORTC classification of cutaneous lymphomas. Blood 2005; 105: 3768-3785.
• Fink-Puches R, Zenahlik P, Bäck B et al. Primary cutaneous lymphomas: applicability of current classification schemes (European Organization for Research and Treatment of Cancer, World Health Organization) based on clinicopathologic features observed in a large group of patients. Blood 2002; 99: 800-805.
• Hristov AC. Primary cutaneous diffuse large B-cell lymphoma, leg type: diagnostic considerations. Arch Pathol Lab Med 2012; 136: 876-881.
• Brzeziński P, Wass J, White K et al. Dermatology eponyms phenomen/sign – Dictionary (A) –continued. N Dermatol Online 2011; 2: 27-34.
• Brzeziński P, Sanaei-Zadeh H, Shane T et al. Dermatology eponym – phenomen/sign – Dictionary (B). N Dermatol Online 2011; 2: 35-45.
• Abreu Velez AM, Klein AD, Howard MS. Skin appendageal immune reactivity in a case of cutaneous lupus. Our Dermatol Online 2011; 2: 175-180.
• Abreu Velez AM, Jackson BL, Velasquez Cantillo KL et al. Merkel cell carcinoma versus metastatic small cell primary bronchogenic carcinoma. Our Dermatol Online 2013; 4: 64-71.
• Oliveira A, Caetano M, Alves R, et al. Letter: Primary cutaneous marginal zone B cell lymphoma of the face: a challenging diagnosis. Dermatol Online J 2012; 18: 12.
• Bandyopadhyay R, Bandyopadhyay SK, Dhua D et al. Primary cutaneous precursor B-cell lymphoblastic lymphoma with late dissemination. Singapore Med J 2011; 52: e258-261.

• Document Type: report