Problems of anticoagulant therapy in elderly cancer patients with atrial fibrillation and hemorrhagic stroke

• Authors: Marina F. Ballyuzek , Maria V. Mashkova
• Languages of publication: EN

Abstracts

EN

The problems of antithrombotic and first of all, anticoagulant therapy in patients with concomitant oncological and cardiovascular pathology, especially in gerontological practice, remain to be unsolved. The need to use anticoagulants is dictated by a high risk of thromboembolism in cancer patients combined with age-associated atrial fibrillation. The risk of hemorrhage increases with the age; moreover, there is a risk of dangerous drug interactions due to the need of polymorbid pathology treatment. Thus, the clinical situation sometimes creates difficulties in choosing a proper tactic in patient management and following the existing treatment standards. A clinical case of a patient of an elder age with the recurrence of lung cancer, which has an established high-risk of thromboembolism, and with paroxysmal form of atrial fibrillation and new oral anticoagulants treatment, is considered.

Keywords

EN

antithromboticand anticoagulant therapy; cardiooncology; geriatric patients; thromboembolism in cancer patients

Discipline

• MEDICINE: MEDICINE

• Publisher: Medical Education
• Journal: OncoReview
• Year: 2017
• Volume: 7
• Issue: 4
• Pages: 168-170

Contributors

author

Marina F. Ballyuzek

• St. Petersburg Clinical Hospital, Russian Academy of Sciences, Russia; St. Petersburg State University, Medical Faculty, St. Petersburg, Russia

author

Maria V. Mashkova

• St. Petersburg Clinical Hospital, Russian Academy of Sciences, Russia

References

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• 2. Heidbuchel Hein et al. Updated European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist anticoagulants in patients with non-valvular atrial fibrillation. Europace 2015; 17: 1467-1507.
• 3. Leinonen JV, Emanuelov AK, Platt Y et al. Left atrial appendages from adult hearts contain a reservoir of diverse cardiac progenitor cells. PLoS One 2013; 8:e59228.
• 4. January CT, Wann LS, Alpert JS et al. 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines and the Heart Rhythm Society. Circulation 2014; 130: 2071-2104.

• Document Type: article