PL EN


Preferences help
enabled [disable] Abstract
Number of results
Journal
2014 | 4 | 3 | A121-125
Article title

Merkel cell carcinoma

Content
Title variants
Languages of publication
EN
Abstracts
EN
Merkel cell carcinoma (MCC) is a rare cutaneous malignancy, with aggressive behaviour. The discovery of MCC polyomavirus (MCPyV) provided a major insight into pathogenesis of MCC, as MCPyV is present in most MCC tumours. The primary treatment of locoregional MCC is surgery, and sentinel lymph node biopsy should be performed in all cases at clinical stage I-II. Adjuvant radiotherapy decreases disease recurrences in stage I-III of the disease. Chemotherapy is primarily used for palliation and provides overall response rates of approximately 70%; however, the disease often recurs within a few months. All cases of MCC should be managed in an experienced multidisciplinary setting.
Discipline
Publisher
Journal
Year
Volume
4
Issue
3
Pages
A121-125
Physical description
References
  • The Rockville Merkel Cell Carcinoma Group. Merkel Cell Carcinoma: Recent Progress and Current Priorities on Etiology, Pathogenesis, and Clinical Management. J Clin Oncol 2009; 27: 4201-4026.
  • Zdzienicki M, Falkowski S. Rak z komórek Merkla (neuroendokrynny rak skóry). In: Złośliwe nowotwory skóry. Piotr Rutkowski (ed.). Via Medica, Gdańsk 2011.
  • Ziółkowska E, Pietrusińska E, Biedka M et al. Rak z komórek Merkla. Onkologia w Praktyce Klinicznej 2008; 4: 141-144.
  • Poulsen M. Merkel-cell carcinoma of the skin. Lancet Oncol 2004; 5: 593-599.
  • O’Connor W, Brodland D. Merkel cell carcinoma. Dermatol Surg 1996; 22: 262-267.
  • Suarez C, Rodrigo J, Ferlito A et al. Merkel cell carcinoma of the head and neck. Oral Oncology 2004; 40: 773-779.
  • Pagella F, Semino L, Corno S et al. Merkel cell carcinoma of the auricle. American Journal of Otolaryngology – Head and Neck Medicine and Surgery 2005; 26: 324-326.
  • Rogowska M, Reinfuss M, Blecharz P et al. Rak z komórek Merkla – analiza 13 przypadków. Nowotwory – Journal of Oncology 2010; 60: 527-531.
  • Chiarelli T, Grant-Kels J, Sporn J et al. Unusual presentation of Merkel cell carcinoma. J Am Acad Dermatol 2000; 42: 366-370.
  • Hendrikx S, de Wilde P, Kaanders J et al. Merkel cell carcinoma: in the oral cavity: A case presentation and review of the literature. Oral Oncology Extra 2005; 41: 202-206.
  • Jońska-Gmyrek J, Bobkiewicz P, Gmyrek L et al. Rak sromu z komórek Merkla – opis przypadku i przegląd piśmiennictwa. Ginekol Pol 2013; 84: 385-389.
  • Yamana N, Sueyama H, Hamada M. Cardiac metastasis from Merkel cell skin carcinoma. Int J Clin Oncol 2004; 9: 210-212.
  • Dancey A, Rayatt S, Soon C et al. Merkel cell carcinoma: a report of 34 cases and literature review. J Plastic Reconstr Aesthetic Surgery 2006; 59: 1294-1299.
  • Bickle K, Glass F, Messina J et al. Merkel cell carcinoma: a clinical, histopatologic and immunohistochemic review. Seminars in Cutaneous Medicine and Surgery 2004; 23: 46-53.
  • Edge SB, Byrd DR, Compton CC et al. (eds.) AJCC Cancer Staging Handbook From the AJCC Cancer Staging Manual, 7th ed., Springer New York Dordrecht Heidelberg London, 2010.
  • Komorowski AL, Wysocka J, Wysocki WM. Rak z komórek Merkla. Nowa klasyfikacja TNM (2010 r.). Medycyna Praktyczna Onkologia 2011; 04.
  • Miller SJ, Alam M, Andersen J et al. Merkel Cell Carcinoma. Clinical Practice Guidelines in Oncology. JNCCN 2009; 7: 322-332.
  • Foote M, Harvey J, Porceddu S et al. Effect of radiotherapy dose and volume on relapse in Merkel Cell Cancer of the skin. Int J Radiation Oncology Biol Phys 2010; 77: 677-684.
  • Sattler E, Geimer T, Sick I et al. Sentinel lymph node in Merkel cell carcinoma: To biopsy or not to biopsy? J Dermatol 2013; 40: 374-379.
  • Schneider S, Thurnher D, Erovic BM. Merkel Cell Carcinoma: Interdisciplinary Management of a Rare Disease. J Skin Cancer 2013; 189342.
Document Type
review
Publication order reference
YADDA identifier
bwmeta1.element.psjd-bfc08bd3-319b-4ca6-a453-e3de7611fd3d
Identifiers
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.