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2018 | 18 | 2 | 72-78
Article title

Synthesis, Characterization, In-Vitro Antimicrobial Evaluation and Antioxidant Studies of Some Isoxazoline Derivatives

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EN
Abstracts
EN
Tremendous rise in development of resistance to the antimicrobials has created alarming situation for researchers and clinicians. In this regard, an attempt has been made to develop a series of azole. The present study comprises of design and synthesis of some newer derivatives by incorporating isoxazole nucleus in the pharmacophore and characterizing them physicochemically and by spectral means. The synthesized compounds were structurally characterized on the basis of IR and microanalyses. All of the newly isolated compounds were tested for their antimicrobial activities. The antimicrobial screening using the agar disc diffusion method revealed that the most of the derivatives are the most active. Moreover, the antioxidant activity of these derivatives are also studied using the DPPH radical scavenging methods.
Year
Volume
18
Issue
2
Pages
72-78
Physical description
References
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Document Type
article
Publication order reference
YADDA identifier
bwmeta1.element.psjd-bf8ca94d-f7dd-425c-97b2-2cf5b649a349
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