EMULSIFICATION PARAMETERS STUDY ON MICELLES FORMATION FROM HYDROPHOBICALLY MODIFIED CHITOSAN

• Authors: Agnieszka Piegat , Agata Niemczyk , Agata Goszczyńska
• Languages of publication: EN

Abstracts

EN

A series of N,O-acylated chitosan derivatives were emulsified with different fatty acids. Hydrophobically modified chitosan derivatives were expected to exhibit self-assembly behaviour resulting in micelle formation. Several parameters of the oil-in-water emulsification process were investigated: mixing method, speed and duration, volume oil phase and addition of modifiers. Their influence on micellar Z-average diameter, size distribution and Zeta potential was analysed based on dynamic light scattering measurements. There were various relations between the hydrodynamic behaviour of chitosan derivatives, their chemical structure and the process parameters. Additionally, the obtained micelles could serve as active compound carriers because they encapsulated two model substances, namely ibuprofen and α-tocopherol.

Keywords

EN

amphiphilic properties.; emulsification; hydrophobically modified chitosan; micelles; self-assembly

• Publisher: Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
• Journal: Progress on Chemistry and Application of Chitin and its Derivatives
• Year: 2021
• Volume: 26
• Pages: 178-190

Contributors

author

Agnieszka Piegat

• Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology,

author

Agata Niemczyk

• Faculty of Mechanical Engineering and Mechatronics, West Pomeranian University of Technology,

author

Agata Goszczyńska

• Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology,

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• Document Type: article