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Number of results
2021 | 26 | 178-190

Article title

EMULSIFICATION PARAMETERS STUDY ON MICELLES FORMATION FROM HYDROPHOBICALLY MODIFIED CHITOSAN

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EN

Abstracts

EN
A series of N,O-acylated chitosan derivatives were emulsified with different fatty acids. Hydrophobically modified chitosan derivatives were expected to exhibit self-assembly behaviour resulting in micelle formation. Several parameters of the oil-in-water emulsification process were investigated: mixing method, speed and duration, volume oil phase and addition of modifiers. Their influence on micellar Z-average diameter, size distribution and Zeta potential was analysed based on dynamic light scattering measurements. There were various relations between the hydrodynamic behaviour of chitosan derivatives, their chemical structure and the process parameters. Additionally, the obtained micelles could serve as active compound carriers because they encapsulated two model substances, namely ibuprofen and α-tocopherol.

Year

Volume

26

Pages

178-190

Physical description

Contributors

  • Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology,
  • Faculty of Mechanical Engineering and Mechatronics, West Pomeranian University of Technology,
  • Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology,

References

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Document Type

article

Publication order reference

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YADDA identifier

bwmeta1.element.psjd-bd2e6300-ffa9-4f29-a1a5-75b3390c78ef
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