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2015 | 5 | 4 | A155-159
Article title

Synchronous colorectal cancer

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EN
Abstracts
EN
Colorectal cancer is one of the most common neoplasms worldwide. It is still characterized by high mortality and causes ¼ of deaths due to neoplasms. Synchronous cancer is defined as presence of more than one cancer focus (not metastatic) in a patient at the same time. Prevalence of synchronous cancer amounts to 1.1–8.1% of all colorectal carcinomas. More often it affects elderly people and men. Risk factors include inflammatory bowel diseases, hereditary non-polyposis colorectal cancer and familial adenomatous polyposis. Molecular mechanisms underlying the synchronous lesions are: microsatellite instability (MSI), P53 and KRAS mutations as well as glutathione S transferase mutations (GST). In this article, we present a case of a 76-year-old woman with synchronous colorectal cancer in the form of tumors of the sigmoid colon and the ascending colon with metastasis in the liver.
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Journal
Year
Volume
5
Issue
4
Pages
A155-159
Physical description
Contributors
  • Clinical Department of Internal Medicine, Department of Public Health in Bytom, Medical University of Silesia Specialized Hospital no. 1 in Bytom, Poland, pawelko147@wp.pl
  • Clinical Department of Internal Medicine, Department of Public Health in Bytom, Medical University of Silesia Specialized Hospital no. 1 in Bytom, Poland
  • Clinical Department of Internal Medicine, Department of Public Health in Bytom, Medical University of Silesia Specialized Hospital no. 1 in Bytom, Poland
author
  • Clinical Department of Internal Medicine, Department of Public Health in Bytom, Medical University of Silesia Specialized Hospital no. 1 in Bytom, Poland
  • Clinical Department of Internal Medicine, Department of Public Health in Bytom, Medical University of Silesia Specialized Hospital no. 1 in Bytom, Poland
  • Clinical Department of Internal Medicine, Department of Public Health in Bytom, Medical University of Silesia Specialized Hospital no. 1 in Bytom, Poland
References
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Document Type
article
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YADDA identifier
bwmeta1.element.psjd-b26ba936-25d1-4e0a-ad59-0dddeb05cd56
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