Synthesis, spectral characterization and biological activity studies of Schiff’s base of 1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-4-amine and its metal complexes

• Authors: Juvansinh J. Jadeja , Mitesh B. Gondaliya , Devang M. Mokariya , Manish Shah
• Languages of publication: EN

Abstracts

EN

N,O,O-donating tridentate ligand was prepared by condensed reaction 1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-4-amine with derivative of salicylaldehyde and its metal complexes with Zn, Cd and Hg, which is highly stable at room temperature and characterized by Mass spectra, IR, 1H and 13C NMR, ESI-MASS and TGA-DTA. Comparatively studies of anti-microbial and anti-fungal activity of different ligand and its metal complex carried out.

Keywords

EN

Schiff Bases; anti-microbial activity; Metal complexes; spectral analysis

Discipline

• CHEMISTRY: CHEMISTRY

• Journal: World Scientific News
• Year: 2016
• Volume: 47
• Issue: 2
• Pages: 123-150

Contributors

author

Juvansinh J. Jadeja

• Chemical Research Laboratory, Chemistry Department, Saurashtra University, Rajkot, India

author

Mitesh B. Gondaliya

• Chemical Research Laboratory, Chemistry Department, Saurashtra University, Rajkot, India

author

Devang M. Mokariya

• Chemical Research Laboratory, Chemistry Department, Saurashtra University, Rajkot, India

author

Manish Shah

• Chemical Research Laboratory, Chemistry Department, Saurashtra University, Rajkot, India,

References

• [1] (a) V. Alexander, Chem. Rev. 95 (1995) 273-342.
• (b) A.D. Granvoskii, A.L. Nivorozhkin, V.I. Minkin, Coord. Chem. Rev.126 (1993) 1-26.
• [2] (a) E.M. Hodnett, W.J. Dunn, J. Med. Chem. 13 (1970) 768-770.
• (b) D. Kessel, A.F.A. Sayyab, E.M.H. Jaffar, A.H.H.A. Lanil, Iraqian J. Sci. 22 (1981) 312-316.
• (c) J. Chakraborty, R.N. Patel, J. Indian Chem. Soc., 73 (1996) 191193.
• [3] (a) A.M. Farghaly, A. Hozza, Pharmazie, 35 (1980) 596-601.
• (b) T. Hitoshi, N. Tamao, A. Hideyuki, F. Manabu, Takayuki, Polyhedron, 16 (1997) 3787-3794.
• [4] M.E. Hossain, M.N. Alam, J. Begum, A.M. Akbar, M. Nazimuddin, F.E. Smith,R.C. Hynes, Inorg.Chim. Acta, 249 (1996) 207-213.
• [5] D. Chiaramonte, J.M. Steiner, J.D. Broussard, K. Baer, S. Gumminger, E.M. Moeller, D.A. Williams, R. Shumway, Can. J. Vet. Res., 67 (2003) 183-188.
• [6] P. N. Yadav, M. A. Demertzis, D. Kovala-Demertzi, S.Skoulika, D. X. West, Inorg. Chim. Acta, 30 (2003) 349.
• [7] M. P. Marques, O. M. Takayanagui, V. L. Lanchote, Braz. J. Med. Biol. Res., 35 (2002) 261.
• [8] (a) D.X. West, H. Gebremedhin, R.J. Butcher, J.P. Jasinski, A.E. Liberta, Polyhedron, 12 (1993) 2489-2497. (b) A.F. Kolodziej, Prog. Inorg. Chem., 41 (1994) 493-598.
• [9] N. Rama, J. Dhaveethu Raja, A. Sakthivel, J. Chem. Sci., 119 (2007) 303-310.
• [10] P.M. Selvakumar, E. Suresh, P.S. Subramanian, Polyhedron, 26 (2007) 749-756.
• [11] R.K. Agarwal, L. Singh, D. Sharma, L. Singh, H. Agarwal, Bioinorg. Chem. Appl., (2006) Article ID 29234.
• [12] N. Raman, A. Kulandaisamy, C. Thangaraja, Trans. Met. Chem., 29 (2004) 129-135.
• [13] K.Z. Ismail, Trans. Met. Chem., 25 (2000) 522-528.
• [14] A. El-Dissouky, A.K. Shehata, G. El-Mahadey, Polyhedron, 16 (1997) 1247-1253.
• [15] G. Shankar, R.R. Premkumar, S.K. Ramalingam, Polyhedron, 5 (1986) 991-994.
• [16] T. Radhakrishnana, P.T. Joseph, C.P. Prabhakaran, J. Inorg. Nucl. Chem., 38 (1986) 2212-2217.
• [17] A. Barry, Procedures and theoretical considerations for testing antimicrobial agents in agar media. in: Lorian (Ed.), Antibiotics in Laboratory Medicine, fifth ed. Williams and Wilkins, Baltimore, (1991).
• [18] National Committee for Clinical Laboratory Standard, NCCLS: Methods for antimicrobial dilution and disk susceptibility testing of infrequently isolated or fastidious bacteria; Approved guideline, Document M45-A, 26(19), Willanova, PA, USA, (1999).

• Document Type: article