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2020 | 142 | 120-134
Article title

Synthesis and biological activity of novel sulfonamides derivatives of various heterocyclic compounds

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EN
Abstracts
EN
A novel series of Sulfonamide embedded heterocyclic derivatives were synthesized and well characterized by using 1H NMR, 13C NMR and IR spectroscopic techniques. All the new synthesized compounds were evaluated to their anti-bacterial, anti-fungal and anti- malarial activities. Noticeably, compound 5b was the most potent compound in vitro anti-microbial (S. aureus) with a MTCC value of 96 microgram/ml and compounds 5g and 5j showed most potent activity in vitro anti-fungal (C. albicans) with a MTCC value of 277microgram/ml. Similarly, compound 5e showed high potent activity of anti-malarial (P. falciparum) with mean IC50 value as compared to other synthesized derivatives.
Year
Volume
142
Pages
120-134
Physical description
Contributors
  • Department of Chemistry, Faculty of Basic and Applied Science, Madhav University, Madhav Hills N.H.- 27,Opp. Banas River Bridge, P.O. Bharja (Aburoad), Tehsil-Pindwara, District - Sirohi (Rajasthan), Pin – 307026, India
  • Department of Chemistry, Faculty of Basic and Applied Science, Madhav University, Madhav Hills N.H.- 27,Opp. Banas River Bridge, P.O. Bharja (Aburoad), Tehsil-Pindwara, District - Sirohi (Rajasthan), Pin – 307026, India
  • Department of Chemistry, Faculty of Basic and Applied Science, Madhav University, Madhav Hills N.H.- 27,Opp. Banas River Bridge, P.O. Bharja (Aburoad), Tehsil-Pindwara, District - Sirohi (Rajasthan), Pin – 307026, India
References
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Document Type
article
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.psjd-a7f1da6d-5235-4814-b6db-7db2dd952356
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