Effect of aqueous extract of Raphia vinifera P.Beauv. mesocarp on glucose and triglyceride levels of Wistar albino rats

• Authors: Asambo Ambah , Mr Frank-Oputu Ayibaene
• Languages of publication: EN

Abstracts

EN

The aim of this study was to evaluate the effect of Raphia vinifera mesocarp extract on glucose and triglyceride levels in Wistar albino rats. A total of 12 healthy female rats were randomly assigned into four groups of three animals each. The control group received 2 ml of distilled water, while Groups 1, 2, and 3 received 2 ml each of Raphia vinifera mesocarp extract at concentrations of 25%, 20%, and 15%, respectively. Following a 10-day treatment period, blood samples were collected for the determination of plasma glucose and triglyceride levels. Data were analysed using one-way ANOVA. The results revealed a statistically significant increase in glucose levels in the extract-treated groups (P < 0.05), while no significant differences were observed in triglyceride levels across groups (P ≥ 0.05). Conclusively, the findings suggest that aqueous extract of Raphia vinifera mesocarp may elevate plasma glucose levels, indicating its potential utility in the management of hypoglycemia rather than hyperglycemia or dyslipidemia.

Keywords

EN

Diabetes; Extracts; Glucose; Mesocarp; Raphia vinifera; triglyceride profile

Discipline

• BIOCHEMISTRY: BIOCHEMISTRY

• Publisher: Scientific Publishing House „DARWIN”
• Journal: World News of Natural Sciences
• Year: 2025
• Volume: 61
• Issue: 2
• Pages: 348-358

Contributors

author

Asambo Ambah

• Department of Biochemistry, Faculty of Basic Medical Sciences, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria

author

Mr Frank-Oputu Ayibaene

• Department of Biochemistry, Faculty of Basic Medical Sciences, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria

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• Document Type: article