Computational analyzing of 13 trace elemental concentrations in ten anti-skin disease traditional herbs from Telangana using ED-XRF-Technique

• Authors: S. Jyothsna , D. Sammaiah
• Languages of publication: EN

Abstracts

EN

Skin diseases present a major health concern worldwide. In recent years, herbal plants have been proved a good source of highly effective conventional agents for the treatment of several skin diseases. In this research study, the popular ED-XRF Technique was used for estimation of 13 trace elemental concentrations in 10 various Anti-skin diseases herbal plants, due to its multi-elemental, high sensitivity and low detection limits. Thirteen major and minor or trace elements namely P, K, Cl, Mn, Ca, Cu, Fe, Zn, Rb, Sr, Br and Se were identified and concentrations measured in ppm levels and further we have discussed a possible link between the curative properties of herbal plants and their elemental concentrations. In the present work, the concentration of S, Ca, Mn, Fe, and Zn was found at an enormous excess amount while Cu and Se found at low concentrations in selected medicinal plants when compared with the control sample (NIST Apple leaf). Notably, the present findings exhibited that, the curative potentials of these herbal plants used for curing various kinds of skin ailments since they are found to containing a rich amount of Mn, Ca, Zn, Se, Cu and Fe.

Keywords

EN

Aloe vera; Alstonia scholaris; Andrographis paniculata; Annona muricata; Butea monosperma; Clerodendrum serratum; Coccinia grandis; Conventional practices; Curcuma longa; EDXRF-spectrometer; Medicinal herbs; Moringa oleifera; Pongamia pinnata; Skin-ailments; Trace elements; nEXT-software

Discipline

• BOTANY: BOTANY

• Publisher: Scientific Publishing House „DARWIN”
• Journal: World Scientific News
• Year: 2022
• Volume: 164
• Pages: 17-43

Contributors

author

S. Jyothsna

• Department of Physics, Kakatiya University, Warangal - 506009, TS, India

author

D. Sammaiah

• Department of Botany, Govt. Degree College, Mulugu - 506343, TS, India

References

• [1] De Wet, H., Nciki, S. & van Vuuren, S.F. Medicinal plants used for the treatment of various skin disorders by a rural community in northern Maputaland, South Africa. J Ethnobiology Ethnomedicine 9, 51 (2013). https://doi.org/10.1186/1746-4269-9-51
• [2] Grice, E.A.; Kong, H.H. Conlan, S, Deming, C.B, Davis. J, Young, A.C. Bouffard, G.G. Blakesley, R.W. Murray, P.R. and Green, E.D. 2009 Topographical and temporal diversity of the human skin microbiome. Science 2009, 324(5931), 1190-1192
• [3] Gonzalez-Aspajo, G.; Belkhelfa, H. Haddioui-Hbabi, L. Bourdy, G. Deharo, E. Sacha Inchi oil (Plukenetia volubilis L.) effect on adherence of Staphylococus aureus to human skin explant and keratinocytes in vitro. J Ethnopharmacol. 2015, 171, 330-334
• [4] Malik. K.; Ahmad. M. Zafar, M. Ullah, R. Mahmmod, H.M. Parveen, B. Sultana, S. Nasar Shah, S. and Lubna. An ethnobotanical study of medicinal plants used to treat skin diseases in northern Pakistan. BMC Complement Altern. Med. 2019, 19, 210
• [5] Aziz Shahin.; Koushik Saha, Nasim Sultana, Husna Parvin Nur, Md Aminul Ahsan, Shamim Ahmed, and Md kamal Hossain. Comparative studies of elemental composition in leaves and flowers of Catharanthus roseus growing in Bangladesh. Asian Pac. J. of Trop. Biomed. 2016, 6(1). 50-54
• [6] Zari Shadi.; and Zari, T.A. A review of four common plants used to treat eczema Journal of Medicinal Plants 2015, 9(24), 702-711
• [7] Amar Mubark Ebrahim.; Mohamed Hassan Eltayeb, Hassan Khalid, Haidar Mohamed, Wail Abdalla, Piter Grill, Brenhard Michalkke. Study on selected trace elements and heavy metals in some popular medicinal plants from Sudan, J. Nat. Med. 2012, 66, 671-679
• [8] Schuman, K.; Dietary reference intakes for trace elements revisited. J. Trace Ele. Med. Biol. 2006, 20, 59-61
• [9] Prasad, M.N.V.; Trace elements as contaminants and nutrients: consequences in ecosystems and human health, Wiley, New York, 2008.
• [10] Sattar, S.A.; Reddy, B.S. Rao, V. K. Pradeep, A. S. Raju, G. J. N. Ramanarayana, K. Rao, P.V.M. and Reddy, S.B. Estimation of trace element in some anti-epileptic medicinal plants by PIXE. J. Radio. Nucl. Chem. 2012, 294, 337-341
• [11] Bock, M.; Schmidt, A. Bruckner, T. and Diepgen, T.L. Occupational skin disease in the construction industry. Br. J. Dermatol. 2003, 149 1165-1171
• [12] Khan, K. Y.; Khan, M.A. Niamat, R. Munir, M. Fazal, H. Mazari, P. Seema, N. Bashir, T. Kanwal, A. Ahmed, S.N. Element content analysis of plants of genus Ficus using atomic absorption spectrometer. African Jour. of Pharmacy and Pharmacology, 2011, 5(3), 317-321
• [13] Faizul Haq.; and Rahat Ullah. Comparative determination of trace elements from Allium sativum, Rheum australe and Terminalia chebula by atomic absorption spectroscopy. International Journal of Biosciences 2011, 1(5), 77-82
• [14] WHO (World Health Organization). Trace elements in human nutrition and human health, World Health Organization, Geneva, 1996.
• [15] Wang, C.F. Duo, M.J. Chang, E.E. Yang, J.Y. Essential and Toxic trace elements in the Chinese medicine, Jour. Radio. Nucl. Chem. 1996, 211, 333-347
• [16] Macknin, M.; Zinc Lozenges for the Common Cold Review. Cleveland Clinical Journal of Medicine 1999, 66, 27-32
• [17] Mocchegiani, E.; and Muzzioli, M. Therapeutic Application of zinc in Human Immunodeficiency Virus Against Opportunistic Infections. Journal of Nutrition 2000, 130, 1424-1431
• [18] Rostan, E.F.; Holly, M.D. DeBuys, V. Doren M D and Madey L. Evidence supporting zinc as an important antioxidant for skin. Int. Jour. Dermatology 2002, 41, 606-611
• [19] Sacramento. California Air Resources Board PO Box 2815 CA 95812 2004, 916, 324-8023
• [20] Sato, S; Iron Deficiency: Structural and Micro chemical Changes in Hair, Nail and Skin. Semin. Dermatol. 1991, 10(4). 313-319
• [21] Egharevba, R.K. A; and Ikhatua, M. I. Ethno- Medical Uses of Plants in the Treatment of Various Skin Diseases in Ovia North East, Edo State, Nigeria. Res. Jour. of Agri. and Biol. Scie. 2008, 4(1), 58-64
• [22] Prakash Jay Rajan.; Kshetrimayum Birla Singh, SanjivKumar and Raj Kumar Mishra. Trace element content in the selected medicinal plants traditionally used for curing skin diseases by the natives of Mizoram, India. Asian Pacific Jour. of Tropi. Med. 2014, 7 S410-S414.
• [23] Gowrishankar, R.; Manish Kumar, Vinay Menon, Sai Mangala Divi, Saravanan M, Magudapathy, P. Panigrahi, B.K. Nair, K.G.M. and Venkataramaniah. Trace element studies on Tinospora cordifolia (Menispermaceae), Ocimum Sanctum (Lamiaceae), Moringa Oleifera (Moringaceae), and Phyllanthus Niruri (Euphorbiaceae) Using PIXE Biol. Trace Elem. Res. 2010, 133(3), 357-363
• [24] Jyothsna, S.; Manjula, G. Sateesh Suthari and Nageswara Rao, A.S. Qualitative elemental analysis of selected potential anti-asthmatic medicinal plant taxa using EDXRF technique. Heliyon 2020, 6, e03260.f
• [25] Prashanth Kumar, P.; and Vidhyasagar, G.M. Traditional knowledge on medicinal plants used for the treatment for the skin diseases in Bidar district, Karnataka. Indian Journal of Traditional Knowledge 2008, 7(2), 273-276
• [26] Pekamwar, S.S.; Kalyankar, T.M .and Kokate, S.S. Pharmacological Activities of Coccinia grandis: Review. Jour. of Appl. Pharmaceutical Scie 2013, 3(05), 114-119
• [27] Choi, E.J.; Debnath, T. Tang, Y. Ryu, Y.B. Moon, S.H. and Kim, E.K. Topical application of Moringa oleifera leaf extract ameliorates experimentally induced atopic dermatitis by the regulation of Th1/Th2/Th17 balance. Biomedicine & Pharmacotherapy 2016, 84, 870-877.
• [28] Panda, T.; Mishra, N. and Pradhan, B.K. Folk Knowledge on Medicinal Plants Used for the Treatment of Skin Diseases in Bhadrak District of Odisha, India. Med. Aromat. Plants 2016, 5 262. doi:10.4172/2167-0412.1000262
• [29] Korpenwar, A.N. Ethnomedicinal Plants Used To Cure Skin Diseases In Ambabarwa Wild Life Sanctuary Area Of Buldhana District (M.S.), India. Inter. Jour. of Recent Trends in Scie. and Technology 2012, 2(3), 36-39
• [30] Baliga, M.S. Review of the phytochemical, pharmacological and toxicological properties of Alstonia Scholaris Linn. R. Br (Saptaparna). Chin. J. Integr. Med. (2012). https://doi.org/10.1007/s11655-011-0947-0
• [31] Soheil Zorofchian, M.; Mehran Fadaeinasab, Sonia Nikzad, Gokula Mohan, Hapipah Mohd Ali and Habsah Abdul. Annona muricata (Annonaceae): A review of its Traditional uses, isolated acetogenins and biological activities. Int Jour Mol Science 2015, 16(7), 15625-15658
• [32] Sudarshan, M.; Ram, S.S. Majumdar, S. Maity, J.P. Ray, J.G. and Chakraborty, A. Energy-dispersive X-ray fluorescence-A tool for interdisciplinary research PRAMANA Journal of Physics 2011, 76, 241-247
• [33] Lin, A.N.; Reimer, R.J. and Carter, D.M. Sulfur Revisited. Jour. of Acad. Dermatol. 1988, 18(3), 553-558
• [34] Gupta Aditya and Nicol Karyn The use of Sulfur in dermatology. Jour. of Drugs in Dermatologyn 2004, 3(4), 457-431
• [35] Chaturvedi, H.C.; Agnihotri, S. Sharma, M. Sharma, A.K. Jain, M. Gupta, P. and Kidwai N.R. Induced nucellar embryogenesis in vitro for clonal multiplication of Mangifera indica L. var. Ambalavi: A dwarfing rootstock. Indian J. Biotechnol. 2004, 3(2), 221-228.
• [36] Uma, C.; and Sekar, K.G. Growth, Nodulation and yield of mug bean (Vignaradiatal) as influenced by coin oculation with rhizobium and plant growth promoting rhizo bacteria. International Journal of Advances in Pharmacy, Biology and Chemistry 2014, 3(3), 586
• [37] Aschner, M.; and Dorman, D. C. Manganese: Pharmacokinetics and molecular mechanisms of brain uptake. Toxicological Reviews 2007, 25, 147-154
• [38] Wada Osamu. What are Trace Eements? Their deficiency and excess states. JMAJ 2004, 47(8), 351-358
• [39] Dutta, T.K.; and Mukta, V. Trace elements Med. Update 2012, 22 353-357.
• [40] Michaelsson, G.; Ljunghall, K. and Danielson, B. G. Zinc in epidermis and dermis in healthy subjects. Acta Dermato-Venerelogica 1980, 60(4), 295-299
• [41] Artiunin, G.P.; Rocheva, I.I. Leshtaeva, N.R. Mikhaleva, V. S. and Lazareva, N.V. Respiratory system diseases in workers in the production of nickel, cobalt and copper. Med. Tr. Prom Ekol. 1998, 11 32-36
• [42] Olivares, M.; Uauy, R. Icaza, G. and Gonzalez, M. Models to evaluate health risks derived from copper exposure/intake in humans, In Copper Transport and its Disorders, edited by Leone and Mercer, New York, Kluwer Academic/Plenum Publishers, 1999.
• [43] Rafferty, T.S.; McKenzie, R.C. Hunter, J.A. Howie, A.F. Arthur, J.R. Nicol, F. and Beckett, G.J. Defferential epression of selenoprotiens by human skin cells and protection by selenium from UVB-radiation induced cell death Biochem. Jour. 1998, 332(Pt1), 231-236
• [44] McKenzie, R.C.; Selenium Ultravoilet Radiation and the skin. Clin. Exp. Dermatol. 2000, 25(8), 631-636
• [45] Nazemi, L.; The role of Selenium deficiency and toxicology in dermatology 7th European Dermatology Congress (June 13th -14th, 2016) Alicante, Spain. Cli. Exp. Dermatol. Res. 2016.
• [46] Srinivasu, Ch. Ch., Raju, T.P. Babu, N.G. Ram, S.S. Sudershan, M. and Das, N.L. Estimation of elemental concentrations of Indian medicinal plants using energy dispersive X-Ray fluorescence (EDXRF) technique. Int. J. Multidisci. Res. Dev. 2016, 30 299-304.
• [47] Raju, G.J.N.; Sarita, P. Chandra Sekhara Rao, J. Rao, K.C.B. and Bhuloka Reddy, S. Correlation of trace elemental content in selected anticancer medicinal plants with their curative ability using particle induced X-ray emission (PIXE). Journal of Medicinal Plants Research 2013, 7(16), 1081-1086

• Document Type: article