Effect of Raw Extract of Clitoria ternatea L. on Sexual Stimulate Test of Female Genital Tract in Rat
Languages of publication
Clitoria ternatea have no toxicity as per the earlier reports of sexual stimulate effect of traditional medicine used by the tribal and fishery village women’s of Point Calimere Wildlife Sanctuary, Nagapattinam district, Southern India. In the present study, reproductive stimuli and fertility effect of raw extract of Clitoria ternatea (RECT) was administered orally at the doses of 250 mg/kg body weight of female rat for a period of 30 days and normal clean water (Normal slain 0.9%, 0.5 ml/kg per day) to control groups. There were no significance changes in the body weight of RECT treated group when compared to control group. RECT treated female rat group vigorously mated with male when allowed on estrus phase of female rat observed in vaginal smears. The serum estradiol level was increased (P < 0.05) significantly. Administered the RECT showed no significant change in the biochemical parameters and hematological parameters of RBC, WBC count when compared to control group. It is concluded that the test of RECT could be due to its reproductive effect in female rat.
-  Adaay M.H and Mosa A.R (2012). Evolution of the effect of aqueous extract Tribulus terrestris on some reproductive parameter in rat. J. Mater. Environ. Sci. 3(6), 1153-1162.
-  Arthur S. (1980). Technical Hematology, 3rd Eds., Lippincott Company, Philadelphia, Toronto, 49-95.
-  Barbieri RL. The initial fertility consultation: Recommendations concerning cigarette smoking, body mass index, and alcohol and caffeine consumption. American Journal of Obstetrics and Gynecology 185(5): 1168-1173 November 2001 Volume 185, Issue 5, Pages 1168–1173
-  Behringer MP (1973). Techniques and Materials in Biology, McGrawHill Publishers, New York, pp. 122-132.
-  Chandru G., Jayakumar, K and Navaneethakannan, D. Effect of Raw Extract of Hybanthus enneaspermus (L.) F. Muell. on the Fertility Test in Female Mice. (Mus musculus) World Scientific News 65 (2017) 160-170
-  Deir B. P. Fitoterapiajum 74(4) (2003) 345-9.
-  El-Ashmawy, I M., Saleh, A., Salama, O M. (2007). Effect of Marjoram volatile oil and grape seed extract on Ethanol toxicity in male rat. Basic clinical. Pharmaco & Toxico. 101(5), 320-327
-  Gnoth C, Godehardt E, Frnk G (2005). Definition and prevalence of sub fertility and infertility. Hum Reprod 20(5), 1144-1147.
-  Haseena Bhanus, Meena Bai M, Pallavi C, Thyagaraju K (2011). Suppression of Paracetamol Toxicity by antitoxidant principles of Hybanthus enneaspermus (L.) F.Muell.in mice blood and liver. Int. Jr. Pharm. & Pharmacetamol. Sci. 4, 90-94.
-  Hassid WZ and Abrahams (1957). Determination of glucose in; colowick, s.p., and Kaplan. N.O(eds) Methods in Encymology volume III. Acadamic press, New York, p-34.
-  Lowery OH, Rose brought NJ, Farr AL, Randall RJ (1951). Protein Measurement with Folinphenol reagent, J. Biol. Chem. 193, 265-75.
-  Millheiser LS, Helmer AE, Quintero RB W, estphalL M, Milki AA, Lathi RB (2010). Is infertility a risk factor for female sexual dysfunction. FertilSteril 94, 2022-2025
-  Mozafar Khazaei, Azadeh Montaseri, Mohammad Rasool Khazaei and Masumesh Khanahmadi (2011). Fertility and infertility Research center, Kermanshah University of Medical Sciences, Kermanashah, Iran. Vol 5, No 3, Oct-Dec, PP. 122-127.
-  Trease W, Evans C (2002). Pharmacognosy Tribulus terrestris distinguish from wild parameter (13th ed). ELBS with Tindall.UK
-  Watcho P, Wankeu-Nyah M, Nguelefack TB, Tapondjou L, Teponno R, Kamanyi A (2007). Pro-sexual effects of Dracaena arborea (Wild) Ling (Dracaenaceae) in sexually experienced female male mice. Pharmacologyonline 1, 400-419.
-  Zlatkis A, Zak B, Boyle GJ (1953). A simple method for isolation and purification of total lipids from animal tissue. J. Biol Chem. 226, 497-509.
-  Nisha Mathew, M. G. Anitha, T. S. L. Bala, S. M. Sivakumar, R. Narmadha, M. Kalyanasundaram. Larvicidal activity of Saraca indica, Nyctanthes arbor-tristis, and Clitoria ternatea extracts against three mosquito vector species. Parasitology Research April 2009, Volume 104, Issue 5, pp 1017–1025
-  Boominathan R, Devi BP, Mandal SC (2003) Studies on neuropharmacological effects of Clitoria ternatea Linn. root extract in rats and mice. Natural Prod Sci 9(4): 260–263
-  Fradin MS, Day JF (2002) Comparative efficacy of insect repellents against mosquito bite. New Eng J Med 347(1): 13–18
-  Kelemu S, Cardona C, Segura G (2004) Antimicrobial and insecticidal protein isolated from seeds of Clitoria ternatea, a tropical forage legume. Plant Physiol Biochem 42(11): 867–873
-  Mace GSL (1963) Anaerobic bacteriology for clinical laboratories. Pharmacognosy 23: 89–91
-  Malabadi RB, Mulgund GS, Nataraja K (2005) Screening of antibacterial activity in the extracts of Clitoria ternatea. J Med Arom Plant Sci 1 27(1): 26–29
-  Naeem A, Haque S, Khan RH (2007) Purification and characterization of a novel b-d-galactosides-specific lectin from Clitoria ternatea. Protein J 26(6): 403–413
-  Pandey V, Agrawal V, Raghavendra K, Dash AP (2007) Strong larvicidal activity of three species of Spilanthes (Akarkara) against malaria (Anopheles stephensi Liston, Anopheles culicifacies, species C) and filaria vector (Culex quinquefasciatus Say). Parasitol Res 102(1): 171–174
-  Parimaladevi B, Boominathan R, Mandal SC (2004) Evaluation of antipyretic potential of Clitoria ternatea L. extract in rats. Phytomedicine 11(4): 323–326
-  Sukumar K, Perich MJ, Boobar LR (1991) Botanical derivatives in mosquito control: a Review. J Am Mosq Cont Assoc 7: 210–237
Publication order reference