Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl

PL EN


Preferences help
enabled [disable] Abstract
Number of results

Journal

2017 | 4 | 1 | 44-49

Article title

Dysfunkcja gruczołów Meiboma – wyzwania diagnostyczne i terapeutyczne

Authors

Content

Title variants

EN
Meibomian gland dysfunction. Diagnostic and therapeutic challenges

Languages of publication

PL

Abstracts

PL
Dysfunkcja gruczołów Meiboma (MGD, Meibomian gland dysfunction) jest jednym z najczęściej stwierdzanych schorzeń okulistycznych. Do jej objawów należą: zapalenie, nadmierne wydzielanie i nieprawidłowy skład wydzieliny gruczołów Meiboma. Rosnąca świadomość znaczenia MGD wymusza poszukiwanie skuteczniejszych metod terapii. Pomimo wielu tradycyjnych sposobów leczenia, takich jak ciepłe kompresy i higiena powiek zmniejszająca ilość zalegającej wydzieliny łojowej oraz podawanie antybiotyków i leków przeciwzapalnych wpływających na jakość wydzieliny gruczołowej, terapia MGD pozostaje wyzwaniem. Nowe metody leczenia MGD mogą odegrać istotną rolę w ograniczaniu oznak i objawów klinicznych choroby.
EN
Meibomian gland dysfunction (MGD) is one of the most common disorders encountered by ophthalmologists, and it may involve inflammation, hypersecretion, and abnormal excreta of the meibomian glands. Given the increased recognition of the importance of MGD, great attention has been paid to the therapy of MGD. Although there are a number of traditional treatment options, such as warm compresses and lid hygiene to alleviate the obstructed meibum, and antibiotics and anti-inflammatory agents are used to improve the quality of meibum, the treatment of MGD still remains challenging. These emerging treatment options for MGD may play an important role in alleviating the clinical symptoms and signs of this disease.

Discipline

Publisher

Journal

Year

Volume

4

Issue

1

Pages

44-49

Physical description

Contributors

  • AUGON Gabinet Okulistyczny w Białymstoku

References

  • 1. The definition and classification of dry eye disease: Report of the definition and classification subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf 2007; 5(2): 75-92.
  • 2. Bron AJ. The Doyne lecture: reflections on the tears. Eye (Lond) 1997; 11(Pt 5): 583-602.
  • 3. Stern ME, Gao J, Siemasko KF, et al. The role of the lacrimal functional unit in the pathophysiology of dry eye. Exp Eye Res 2004; 78: 409-416.
  • 4. Bron AJ, Tiffany JM, Gouveia SM, et al. Functional aspects of the tear film lipid layer. Exp Eye Res 2004; 78(3): 347-360.
  • 5. Butovich IA, Millar TJ, Ham BM. Understanding and analyzing Meibomian lipids. A review. Curr Eye Res 2008; 33(5): 405-420.
  • 6. King-Smith PE, Fink BA, Hill RM, et al. The thickness of the tear film. Curr Eye Res 2004; 29(4-5): 357-368.
  • 7. Den S, Shimizu K, Ikeda T, et al. Association between meibomian gland changes and aging, sex, or tear function. Cornea 2006; 25(6): 651-655.
  • 8. Matsumoto Y, Dogru M, Goto E, et al. Alterations of the tear film and ocular surface health in chronic smokers. Eye 2008; 22(7): 961- 968. DOI: 10.1038/eye.2008.78.
  • 9. Schaumberg DA, Buring JE, Sullivan DA, Reza Dana M. Hormone replacement therapy and dry eye syndrome. JAMA 2001; 286(17): 2114-2119.
  • 10. Suzuki T, Schirra F, Richards SM, et al. Estrogen and progesterone control of gene expression in the mouse meibomian gland. Invest Ophthalmol Vis Sci 2008; 49(5): 1797-1808. DOI: 10.1167/iovs.07-1458.
  • 11. Madden LC, Tomlinson A, Simmons PA. Effect of humidity variations in a controlled environment chamber on tear evaporation after dry eye therapy. Eye Contact Lens 2013; 39(2): 169-174.
  • 12. Lee S, Lam S, Luk F. Investigation of cabin air quality in commercial aircrafts. Proc Healthy Build 2000; 1: 471-476.
  • 13. Mathers WD, Choi D. Cluster analysis of patients with ocular surface disease, blepharitis, and dry eye. Arch Ophthalmol 2004; 122(11): 1700-1704.
  • 14. Arita R, Itoh K, Maeda S, et al. Efficacy of diagnostic criteria for the differential diagnosis between obstructive meibomian gland dysfunction and aqueous deficiency dry eye. Jpn J Ophthalmol 2010; 54(5): 387-391.
  • 15. Pult H, Nichols JJ. A review of meibography. Optom Vis Sci 2012; 89(5): E760-9.
  • 16. Yamaguchi M, Kutsuna M, Uno T, et al. Marx Line: Fluorescein Staining Line on the Inner Lid as Indicator of Meibomian Gland Function. Am J Ophthalmol 2006; 141(4): 669-675. DOI: 10.1016/j.ajo.2005.11.004.
  • 17. Olson MC, Korb DR, Greiner JV. Increase in tear film lipid layer thickness following treatment with warm compresses in patients with meibomian gland dysfunction. Eye Contact Lens 2003; 29(2): 96-99.
  • 18. Lallemand F, Daull P, Benita S, et al. Successfully improving ocular drug delivery using the cationic nanoemulsion, novasorb. J Drug Deliv 2012; 2012: 604204.
  • 19. Akyol-Salman I, Azizi S, Mumcu UY, et al. Comparison of the efficacy of topical N-acetyl-cysteine and a topical steroid-antibiotic combination therapy in the treatment of meibomian gland dysfunction. J Ocul Pharmacol Ther 2012; 28(1): 49-52.
  • 20. Macsai MS. The role of omega-3 dietary supplementation in blepharitis and meibomian gland dysfunction (an AOS thesis). Trans Am Ophthalmol Soc 2008; 106: 336-356.
  • 21. Pflugfelder SC, Solomon A, Stern ME. The diagnosis and management of dry eye: a twenty-five-year review. Cornea 2000; 19: 644-649.
  • 22. Perry HD, Doshi-Carnevale S, Donnenfeld ED, et al. Efficacy of commercially available topical cyclosporine A 0.05% in the treatment of meibomian gland dysfunction. Cornea 2006; 25(2): 171-175.
  • 23. Foulks GN, Borchman D, Yappert M, et al. Topical azithromycin therapy for meibomian gland dysfunction: clinical response and lipid alterations. Cornea 2010; 29(7): 781-788. DOI: 10.1097/ICO.0b013e3181cda38f.
  • 24. Geerling G, Tauber J, Baudouin C, et al. The international workshop on meibomian gland dysfunction: report of the subcommittee on management and treatment of meibomian gland dysfunction. Invest Ophth Vis Sci 2011; 52(4): 2050-2064.
  • 25. Craig JP, Chen YH, Turnbull PR. Prospective trial of intense pulsed light for the treatment of meibomian gland dysfunction. Invest Ophthalmol Vis Sci 2015; 56(3): 1965-1970.

Document Type

article

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.psjd-9bc6ad1f-04f7-4127-97d9-95d024a2c778
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.