Terapia komórkowa w schorzeniach zwyrodnieniowych siatkówki – nadzieje i zagrożenia

• Authors: Anna Machalińska

Title variants

EN

Cell therapy in degenerative retinal diseases: expectations and threats

• Languages of publication: PL

Abstracts

PL

Obecnie brakuje skutecznego leczenia przyczynowego wielu chorób degeneracyjnych siatkówki. Za poprawę morfologii i funkcji degenerującej siatkówki odpowiadają czynniki neurotroficzne wydzielane przez aplikowane komórki, które wykazują dodatkowo wpływ immunomodulujący i redukują odpowiedź zapalną uszkodzonej tkanki. Najlepsze efekty uzyskuje się w początkowym stadium zaawansowania choroby. Pomimo obiecujących wstępnych wyników terapia komórkowa wymaga dalszych badań oceniających jej skuteczność i długoterminowe bezpieczeństwo. Ponadto powinna być prowadzona tylko w ramach bezpłatnych badań klinicznych w certyfikowanych ośrodkach naukowo-badawczych po uzyskaniu świadomej zgody pacjenta na leczenie.

EN

Currently, for many retinal degenerative diseases there is no effective treatment based on disease etiology. Neurotrophic factors secreted by the applied cells are responsible for improved morphology and function of degenerative retina. Moreover, these cells present immunomodulatory effect and reduce the inflammatory response of the damaged tissue. The best effect is obtained at the initial stage of the disease. Despite promising preliminary results, cell therapy requires further investigation to evaluate its efficacy and long-term safety. It is worth to underline that cell therapy should be conducted only as part of free clinical trials in certified research centers after obtaining the patient's informed consent for treatment

Keywords

EN

komórki macierzyste; terapia komórkowa; zwyrodnienie barwnikowe siatkówki

Discipline

• MEDICINE: MEDICINE

• Publisher: Medical Education
• Journal: OphthaTherapy
• Year: 2020
• Volume: 7
• Issue: 1
• Pages: 30-35

Contributors

author

Anna Machalińska

• I Katedra i Klinika Okulistyki, Pomorski Uniwersytet Medyczny w Szczecinie

References

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• Document Type: article