THE INFLUENCE OF THE TYPE SOLVENT ON THE STRUCTURE OF CHITOSAN BLENDS WITH HYALURONIC ACID

• Authors: Katarzyna Lewandowska , Alina Sionkowska , Sylwia Grabska
• Languages of publication: EN

Abstracts

EN

The influence of the type solvent on the structure of chitosan, hyaluronic acid and their blend films was investigated. Aqueous acetic acid, hydrochloric acid, sodium chloride and aqueous acetic acid/NaCl were used as solvents for chitosan, hyaluronic acid and Ch/HA solution blends. Ch, HA and their blend films were prepared by casting technique. The homogeneity and morphology of chitosan blends were ascertained from the tapping-mode atomic force microscopy (AFM) and scanning electron microscopy (SEM). The changes of topography images are considered by determining the root mean square (RMS, Rq) deviation in the image data. The surface roughness of chitosan, hyaluronic acid and Ch/HA blended films was altered by mixing. The structure of chitosan blends with hyaluronic acid depends on the blend composition and on the solvent used for preparing the blend.

Keywords

EN

chitosan; hyaluronic acid; microscopy.; polymer blends; surface properties

• Publisher: Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
• Journal: Progress on Chemistry and Application of Chitin and its Derivatives
• Year: 2016
• Volume: 21
• Pages: 147-153

Contributors

author

Katarzyna Lewandowska

• Nicolaus Copernicus University in Toruń, Faculty of Chemistry, Department of Chemistry of Biomaterials and Cosmetics, 7 Gagarin Street, 87-100 Toruń Poland

author

Alina Sionkowska

• Nicolaus Copernicus University in Toruń, Faculty of Chemistry, Department of Chemistry of Biomaterials and Cosmetics, 7 Gagarin Street, 87-100 Toruń Poland

author

Sylwia Grabska

• Nicolaus Copernicus University in Toruń, Faculty of Chemistry, Department of Chemistry of Biomaterials and Cosmetics, 7 Gagarin Street, 87-100 Toruń Poland

References

• [1] Liu H, Yin Y, Yao K, Ma D, Cui L, Cao Y; (2004) Influence of the concentration of hyaluronic acid on the properties and biocompatibility of Cs-Gel-HA membranes. Biomaterials 25, 3523-3530. DOI: 10.1016/j.biomaterials.2003.09.102
• [2] Schanté CE, Zuber G, Herlin C, Vandamme TE; (2011) Chemical modifications of hyaluronic acid for the a broad range of biomedical applications. Carbohydr Polym 85, 469-489.DOI: 10.1016/j.carbp11.03.019
• [3] Rinaudo M; (2008) Review Main properties and current applications of some polysaccharides as biomaterials. Polym Int 57, 397-430. DOI: 10.1002/pi.2378
• [4] Lewandowska K, Sionkowska A, Grabska S; (2015) Influence of the intermolecular interaction on physico-chemical properties of chitosan/hyaluronic acid blends. Progress on Chemistry and Application of Chitin and Its Derivatives, Vol. XX, pp. 170-176. DOI: 10.15259/PCACD.20.16
• [5] Lewandowska K, Sionkowska A, Grabska S; (2015) Chitosan blends containing hyaluronic acid and collagen. Compatibility behaviour. J Mol Liq 212, 879-884. DOI: 10.1016/j.molliq.2015.10.047
• [6] Christopoulou V, Papanagopoulos D, Dondos A; (1998) Towards a better mixing of two incompatible polymers by casting form solution without compatibilizer. J Polym Sci Part B: Polym Phys 36 1051-1060. DOI: 10.1002/(SICI)1099-0488(19980430)36:6<1051::AID-POLB13>3.0.CO;2-5
• [7] Dondos A, Christopoulou V, Papanagopoulos D; (1999) The influence of the molecular mass of two incompatible polymers on their miscibility in the solid state without compatibilizer after casting form solution. J Polym Sci Part B: Polym Phys 37, 379-387. DOI: 10.1002/(SICI)1099-0488(19990215)37:4<379::AID-POLB11>3.0.CO;2-K
• [8] Lewandowska K; (2012) Surface studies of microcrystalline chitosan/poly(vinyl alcohol) mixtures. Appl Surf Sci 263, 115-123. DOI: 10.1016/j.apsusc.2012.09.011
• [9] Katti KS, Katti DR, Dash R; (2008) Synthesis and characterization of a novel chitosan/montmorillonite/hydroxyapatite nanocomposite for bone tissue engineering. Biomed Mater 3, 1-12. DOI: 10.1088/1748-6041/3/3/034122
• [10] Lewandowska K, Sionkowska A, Grabska S, Kaczmarek B, Michalska M; (2016) The miscibility of collagen/hyaluronic acid/chitosan blends investigated in dilute solutions and solids. J Mol Liq in press. DOI: 10.1016/j.molliq.2016.05.009

• Document Type: article