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2016 | 21 | 147-153
Article title

THE INFLUENCE OF THE TYPE SOLVENT ON THE STRUCTURE OF CHITOSAN BLENDS WITH HYALURONIC ACID

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EN
Abstracts
EN
The influence of the type solvent on the structure of chitosan, hyaluronic acid and their blend films was investigated. Aqueous acetic acid, hydrochloric acid, sodium chloride and aqueous acetic acid/NaCl were used as solvents for chitosan, hyaluronic acid and Ch/HA solution blends. Ch, HA and their blend films were prepared by casting technique. The homogeneity and morphology of chitosan blends were ascertained from the tapping-mode atomic force microscopy (AFM) and scanning electron microscopy (SEM). The changes of topography images are considered by determining the root mean square (RMS, Rq) deviation in the image data. The surface roughness of chitosan, hyaluronic acid and Ch/HA blended films was altered by mixing. The structure of chitosan blends with hyaluronic acid depends on the blend composition and on the solvent used for preparing the blend.
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Year
Volume
21
Pages
147-153
Physical description
Contributors
  • Nicolaus Copernicus University in Toruń, Faculty of Chemistry, Department of Chemistry of Biomaterials and Cosmetics, 7 Gagarin Street, 87-100 Toruń Poland, reol@chem.umk.pl
  • Nicolaus Copernicus University in Toruń, Faculty of Chemistry, Department of Chemistry of Biomaterials and Cosmetics, 7 Gagarin Street, 87-100 Toruń Poland
  • Nicolaus Copernicus University in Toruń, Faculty of Chemistry, Department of Chemistry of Biomaterials and Cosmetics, 7 Gagarin Street, 87-100 Toruń Poland
References
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  • [2] Schanté CE, Zuber G, Herlin C, Vandamme TE; (2011) Chemical modifications of hyaluronic acid for the a broad range of biomedical applications. Carbohydr Polym 85, 469-489.DOI: 10.1016/j.carbp11.03.019
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  • [4] Lewandowska K, Sionkowska A, Grabska S; (2015) Influence of the intermolecular interaction on physico-chemical properties of chitosan/hyaluronic acid blends. Progress on Chemistry and Application of Chitin and Its Derivatives, Vol. XX, pp. 170-176. DOI: 10.15259/PCACD.20.16
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  • [8] Lewandowska K; (2012) Surface studies of microcrystalline chitosan/poly(vinyl alcohol) mixtures. Appl Surf Sci 263, 115-123. DOI: 10.1016/j.apsusc.2012.09.011
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  • [10] Lewandowska K, Sionkowska A, Grabska S, Kaczmarek B, Michalska M; (2016) The miscibility of collagen/hyaluronic acid/chitosan blends investigated in dilute solutions and solids. J Mol Liq in press. DOI: 10.1016/j.molliq.2016.05.009
Document Type
article
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bwmeta1.element.psjd-92524aee-5fe9-42e5-947a-6f39170c3bbd
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