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2020 | 147 | 35-44
Article title

Solid phase synthesis of novel 1,3,4-oxadiazole derivatives and evaluation of their antimicrobial activity

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A series of 5-(N-Aryl/Arylalkyl)-2-(3-Chclorophenyl)-1,3,4-oxadiazole have been synthesized. The constitution of the products has been delineated by elemental analysis and spectral analyses. All the synthesized compounds were screened for their antibacterial activity against Staphylococcus aureus MTCC-96, Escherichia coli MTCC-443, B. subtilis MTCC-441, P. aeruginosa MTCC-1688, and antifungal activity against Aspergillus niger MTCC-282 and Penicillium different concentration and compared with standards drugs. The minimum inhibition concentration (MIC) of the compounds was studied by micro broth dilution method.
Physical description
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