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This paper presents the synthesis and antibacterial studies some novel halogenated Platinum (II) complexes of active Schiff’s base ligands of the type [Pt(L1H)2]Cl2, [Pt(L2H)2]Cl2 and[Pt(L)2] derived from 5-Bromo Isatin. Where L1H= hydrazinecarbothiamide of 5-bromoindolinedione and L2H = hydrazinecarboxamide of 5-bromoindolinedione. All complexes reported here had been characterised by 1H NMR and IR spectral studies. Molar conductance studies support the 1:2 natures of these complexes. Pt (II) complexes are diamagnetic in nature and showing square planner geometry. The IR spectral data reveals that both the Schiff’s bases (L1H and L2H) behave as bidentate ligands and are co-ordinated to Pt (II) metal through the sulfur and hydrogenic nitrogen atom.all the new synthesized compounds were screened for antibacterial activity against four of the test organisms like Bacillus pumilus, Micrococcus Lutes, E. coli and Salmonella abony
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32-43
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- Department of Chemistry, Bhavan’s College, Munshi Nagar, Andheri (West), Mumbai 400058, India
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- Department of Chemistry, Bhavan’s College, Munshi Nagar, Andheri (West), Mumbai 400058, India
author
- Department of Chemistry, Bhavan’s College, Munshi Nagar, Andheri (West), Mumbai 400058, India
author
- Department of Chemistry, Bhavan’s College, Munshi Nagar, Andheri (West), Mumbai 400058, India, pravinsingare@gmail.com
References
- [1] Rosenberg B., Vancamp L., Krigas T., Nature, 205 (1965) 698.
- [2] Jakupec M., Keppler B.K., Sigel A., Sigel H. (Eds.), Metal Ions in Biological Systems, vol. 42, Marcel Dekker Inc. (2004).
- [3] Butour S., Wimmer F., Wimmer F., Castan P., Chemico- Biological Interactions.,104 (1997)165.
- [4] Bansal A. Singh R.V., Synth React Inorg Met-Org Chem., 31(2001)381.
- [5] Laly S., Parameswaran G., Asian J. Chem., 5 (1993) 712.
- [6] Somogyi L. Bull. Chem. Soc. Jpn., 74 (2001) 873.
- [7] Da Silva J. F. M., Garden S. J., Pinto A. C., J. Braz. Chem. Soc., 12 (2001) 273.
- [8] Chiyanzu I., Clarkson, C., Smith, P. J., Lehman, J., Gut, J., Rosenthal, P. J., Chibale, K., Bioorg. Med. Chem., 13 (2005)3249.
- [9] Cerchiaro G., Micke G. A., Tavares, M. F. M., Ferriera, A. M. D. C., J. Mol. Catal. A: Chem., 221 (2004) 29.
- [10] Varma R. S., Nobles W. L., J. Med. Chem., 10 (1967) 510.
- [11] Pandeya S. N., Sriram D., Acta. Pharm. Turc., 40 (1998) 33.
- [12] Pandeya S. N., Sriram D., Nath G., De Clercq, E., Eur. J. Pharm. Sci., 9 (1999) 25.
- [13] Teitz, Y., Ronen D., Vansover A., Stematsky T., Riggs J. L., Antiviral Res., 24 (1994) 305.
- [14] Varma R.S., Pandeya R. K., Indian J. Pharm. Sci., 46 (1982) 132.
- [15] Alam M., Younas M., Zafar M.A., Naeem, Pak. J. Sci. Ind. Res., 32 (1989) 246.
- [16] Smolders R.R., Waefelaer A., Francart D., Ing. Chim. (Brussels), 64 (1982)5.
- [17] Md. RabiulIsmlam, Mohammad Mohsin, Bangladesh. J .Pharmacol., 2 (2007) 7.
- [18] Gustavson, J. Prakt. Chem., 37(1883) 108.
- [19] Kohler T., Am. Chem. Soc., 24 (1900) 385.
- [20] Bhagat S., Sharma R., Sawant D.M., Sharma L., Journal of Molecular Catalysis A, 244 (2006) 20.
- [21] Raval A.A., Shah N.M., J. Org. Chem., 22 (1975) 305.
- [22] Dershowitz S., Prokauer S., J. Org. Chem., 26 (1961) 3595.
- [23] Utale P.S., Raghuwanshi P.B., Doshi A.G., Asian. J Chem., 10 (1998) 597.
- [24] Naik S.M., Naik H.B., Orient. J Chem., 14 (1998) 167.
- [25] Sriram D., Yogeeswari P., Thirumurugan. R.S., Bioorg. Med. Chem. Lett., 14 (2004)3923.
- [26] Singh H.P., Chauhan C.S., Pandeya S.N., Sharma C.S., Srivastava B., Singhal M., Der Pharm. Lett. 2 (2004) 460.
- [27] Kovala-Demertzi D., Boccarelli A., Demertzis M.A., Coluccia M., Chemotherapy, 53 (2007)148.
- [28] Khan S.A., Asiri A.M., Khan A.A., Khan K.A., Zayed M.A. M., Asian Journal of Chemistry, 25 (2013) 8643.
- [29] Vinod K.S., Shipra S., Ankita S., Journal of Bioinorganic Chemistry Applications, 13 (2003) 1.
- [30] Turdor R., Aurelian G., Anca N., Rodica G., Oriental Journal of Chemistry, 52 (2007) 782.
- [31] Sulekh C., Umendra K., Verma H.S., Oriental Journal of Chemistry, 19 (2003) 355.
- [32] Finch R.A., Liu M.C., Cory A.H., Cory J.G., Sartorelli A.C., Adv. Enzyme Regul., 39 (1999)3.
- [33] Nutting C.M., van Herpen C.M.L., Miah A.B, Bhide S.A., Machiels J.P., Buter J., Kelly C., de Raucourt D., Harrington K. J., Annals of Oncology, 20 (2009) 1275.
- [34] Reddy V., Patil N., Patil B.R., J. Ind. Council Chem. 23 (2006) 1.
- [35] Pandeya S.N., Mishra V., Singh P.N., Rupainwar D.C., Pharmacology, 37 (1998)17.
- [36] Kavanagh F., (Editor) “Analytical Microbology” Academic Press Inc., New York (1963) p.126.
- [37] Leovac V.M., Jevtovic V.S., Jovanovic L.S., Bogdanovic S., Journal of Serbian Chemistry Society, 70 (2005) 394.
- [38] Soumitra K.S., Om P.P., Bimal K.S., Journal of Transition Metal Chemistry, 23 (1998) 349.
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article
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bwmeta1.element.psjd-8aa67994-2a4c-4906-b9ff-dea5c2eaa268