Antibacterial activity of (PVP-ZrO2) nanocomposite against pathogenic bacteria

• Authors: Raghad Abdullatif Abdulrazaq , Zainab A. Al-Ramadhan , Hadeel H. Khalaf
• Languages of publication: EN

Abstracts

EN

The antibacterial activity of a PVP-ZrO2 nanocomposite was investigated against pathogenic bacteria S. aureus and K. pneumoniae after antibacterial sensitivity was determined and one isolate was chosen that showed more antibiotic resistance. Herein, the Co-culture technique was used to calculate percent reduction of bacteria. The results that were obtained in this method show that ZrO2 nanoparticles have inhibitory effect against pathogenic bacteria gram negative bacteria and gram positive bacteria - with reduction of growth reaching 100% to both S. aureus and K. pnumoniae at 5, 10, 15, 20 and 25% ZrO2, compared with control. The resistance patterns of S. aureus and K.pnuemonia isolates show the Moxifloxacin (MXF) is the best antibiotic for both bacteria - with sensitivity at 100%, while resistance to Ceftriaxone (CRO) is at 90% S. aureus, and at 80% K. pnumoniae. The polymer-nanocomposite was prepared by weight percentage wt. % of (PVP) being dissolved in (10) ml of distilled water, with weight percentages 5%, 10%, 15%, 20% and 25% of ZrO2 nanoparticles added.

Keywords

EN

Anti-Bacterial activity; Antibiotics; Klebsiella pneumoniae; Nanocomposities; PVP; Staphylococcus aureus; ZrO2

Discipline

• BIOCHEMISTRY: BIOCHEMISTRY

• Publisher: Scientific Publishing House „DARWIN”
• Journal: World News of Natural Sciences
• Year: 2018
• Volume: 18
• Issue: 2
• Pages: 187-194

Contributors

author

Raghad Abdullatif Abdulrazaq

• Department of Biology, College of Science, Al-Mustansiriyah University, Baghdad, Iraq

author

Zainab A. Al-Ramadhan

• Department of Physics, College of Education, Al-Mustansiriyah University, Baghdad, Iraq

author

Hadeel H. Khalaf

• Department of Physics, College of Education, Al-Mustansiriyah University, Baghdad, Iraq

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• Document Type: article