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2016 | 54 | 132-152
Article title

Synthesis, effect of substituents and antimicrobial activities of some 4-bromophenyl chalcones

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EN
Abstracts
EN
Elven (E)-1-(4-bromophenyl)-3-(substituted phenyl)-2-propen-1-ones are formed using sodium hydroxide catalyzed Aldol condensation between 4-bromoacetophenone and substituted benzaldehyde. The production of these chalcone compounds are above 90%. These α, β unsaturated ketones were specified by their physical constants and spectral data (UV, IR, 1H and 13C-NMR). Hammett substituted constants (σ, σ+, σI & σR and F and R parameters have been used for correlating the spectral values of these α, β unsaturated ketones by using single and multi-linear regression analysis. The impacts of substituents on the spectral data have been known on statistical analysis. By using Bauer-Kirby method the anti-microbial activities of these (E)-1-(4-bromophenyl)-3-(substituted phenyl)-2-propen-1-ones compounds are estimated.
Year
Volume
54
Pages
132-152
Physical description
References
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Document Type
article
Publication order reference
YADDA identifier
bwmeta1.element.psjd-8a441cb4-55e2-4883-b38c-b12f4e0f59d8
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