Characterization of Catechins from Smilax domingensis Willd. in Cuba

• Authors: Pilar A. Soledispa , José González , Armando Cuéllar , Julio Pérez , Max Monan
• Languages of publication: EN

Abstracts

EN

Gas Chromatography coupled with mass spectrometry was applied to study the fragmentation of selected flavonoids from the ethanolic extract of Smilax domingensis Willd., Smilacaceae, known as zarzaparrilla, after Soxhlet extraction during 20 hours. Compounds belonging to one of the major subgroups found in common plants, i.e. flavanols were studied. Following solvent extraction and derivatization using BSTFA, possibly two different metabolites from the same chemical group were characterized in one analytical run: (+)-catechin and (-)-epicatechin. For the very first time, qualitative data on these analytes in the drug were determined after detailed validation of a sensitive, cheap and reliable GC-MS method.

Keywords

EN

GC/MS; Smilax domingensis; catechins; ethanolic extract; flavanols

Discipline

• PHARMACOLOGY: PHARMACOLOGY

• Publisher: Scientific Publishing House „DARWIN”
• Journal: World News of Natural Sciences
• Year: 2019
• Volume: 23
• Pages: 297-305

Contributors

author

Pilar A. Soledispa

• Faculty of Chemical Sciences, Guayaquil University, Ecuador

author

José González

• Department of Pharmacy, Faculty of Pharmacy and Foods, Havana University, Cuba

author

Armando Cuéllar

• Department of Pharmacy, Faculty of Pharmacy and Foods, Havana University, Cuba

author

Julio Pérez

• National Center of Toxicology (CENATOX), Military Hospital "Carlos J. Finlay", Havana, Cuba

author

Max Monan

• ARVARNAM, 16 lot. les Rosiers, Quartier Thoraille, 97215, Rivière-Salée, Martinica

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• Document Type: article