Zmiany zachodzące w organizmie płazów pod wpływem jonów ołowiu

• Authors: Marta B. Kaczor
• Languages of publication: PL

Abstracts

EN

A contamination of the natural environment is the main problem of the contemporary world. Heavy metal ions are environmentally persistent toxins. A lead-related pathologies (including neurological, hematological, reproductive, circulatory, and immunological pathologies) are the direct result of the oxidative effect of the lead on tissues and cellular components and the generation of reactive oxygen species that decrease level of the available sulfhydryl groups, the antioxidant reserves, can cause nucleic acids damage and initiate lipid peroxidation in cellular membrane. Through binding to thiol groups of allosteric proteins, lead ions can provoke allosteric transition between active and inactive forms. The exposure to heavy metal ions is a direct factor in high mortality rate among amphibians. These animals can become indicators of environmental pollution. The main aim of this paper is to review and summarize the results of performed studies concerning physiological, biochemical and immunological changes in anuran amphibians exposed to the effects of lead ions.

Keywords

EN

biomarkery; hematokryt; krwinki; odporność; ołów; toksyczność; typy toksyczności; układ immunologiczny; układ krwionośny; złogi

Discipline

• BIOLOGY: BIOLOGY

• Publisher: Towarzystwo Doktorantów. Uniwersytet Jagielloński
• Journal: Zeszyty Naukowe Towarzystwa Doktorantów Uniwersytetu Jagiellońskiego. Nauki Ścisłe
• Year: 2012
• Issue: 5
• Pages: 41-55

Contributors

author

Marta B. Kaczor

• Uniwersytet Jagielloński

References

• Arieta M. A., Perí S. I., Apartín C., Rosenberg C. E., Fink N. E., Salibián A., Blood lead concentration and δ-aminolevulinic acid dehydratase activity in adult Bufo arenarum, „Archives of Physiology and Biochemistry” 2000, nr 108.
• Arieta M. A., Bruzzone L., Apartín C., Rosenberg C. E., Fink N. E., Salibián A., Biosensors of inorganic lead exposure and effect in an adult amphibian, „Archives of Environmental Contamination and Toxicology” 2004, nr 46.
• Balding P., Gold E. R., The natural heterohemoagglutinin in the serum of the toad Bufo regularis and its relationship to lower verterbrate immunoglobulins, „Immunology” 1976, nr 30
• Barabowska-Bosiacka I., Chlubek D., Biochemiczne mechanizmy neurotoksycznego działania ołowiu, „Postępy Biochemii” 2006, nr 52.
• Bertini F., Cei J. M., Observaciones electroforéticas en seroproteínas de poblaciones argentinas de Bufo arenarum Hensel, „Review of Society Argent Biology” 1960, nr 36.
• Berzins D. W., Bundy K. J., Bioaccumulation of lead in Xenopus laevis tadpoles from water and sediment, „Environment International” 2002, nr 28.
• Birdsall C. W., Grue C. E., Anderson A., Lead contamination in bullfrog Rana catesbeiana and green frog R. clamitans tadpoles inhabiting highway drainages, „Environmental Pollution” 1986, nr 40A.
• Boguszewska A., Pasternak K., Ołów – wpływ na procesy biochemiczne w organizmie ludzkim, „Annales Universitatis Mariae Curie-Skłodowska Lublin – Polonia” 2004, nr 59.
• Boutilier R. G., Stiffler D. F., Toews D. P., Exchange of respiratory gases, ions, and water in amphibious and aquatic amphibians, „Environmental Physiology of the Amphibians” 1992.
• Burggren W. W., Just J. J., Developmental changes in physiological systems, „Environmental Physiology of the Amphibians” 1992
• Caspers M. L., Siegl G. J., Inhibition by lead of human erythrocyte (Na+/K+) Adenosine triphosphatase associated with binding of 210Pb to membrane fragments, „Biochimica et Biophysica Acta” 1980, nr 600.
• Chiesa M. E., Rosenberg C. E., Fink N. E., Salibián A., Serum protein profile and blood cell counts in adult toads Bufo arenarum (Amphibia: Anura: Bufonidae): Effects of sublethal lead acetate, „Archives of Environmental Contamination and Toxicology” 2006, nr 50.
• Daniell W. E., Stockbridge H. L., Labbe R. F., Woods J. S., Anderson K. E., Bissell D. M., Bloomer J. R., Ellefson R. D., Moore M. R., Pierach C. A., Schreiber W. E., Tefferi A., Franklin G. M., Environmental chemical exposures and disturbances of heme synthesis, „Environmental Health Perspectives” 1997, nr 105.
• . Davic R. D., Gallati W. W., Erythrocyte number in three species of northern Appalachian Desmognathus (Amphibia, Urodela, Plethodonitadae), „Journal of Herpetology” 1979, nr 13.
• Du Pasquier L., The immune system of inverterbrates and verterbrates, „Comparative Biochemistry and Physiology” 2001, nr 129.
• . El-Sokkary G. H., Abdel-Rahman G. H., Kamel E. S., Melatonin protects against leadinduced hepatic and renal toxicity in male rats, „Toxicology” 2005, nr 213
• Fink N. E., Selibàn A., Toxicological studies in adult amphibians: Effects of lead, „Applied Herpetology” 2005, nr 2.
• Fink de Cabutti E. N., Morales V. H., Jmelnitzky C., Basualdo Farjat J. A., de Torres R., Aspectos inmunológicos en portadores crónicos asintomáticos del HbdAg, „Sangre” 1984, nr 29.
• Fragou D., Fragou A., Kouidou S., Njau S., Kovatsi L., Epigenetic mechanism in metal toxicity, „Toxicology Mechanism and Methods” 2011, nr 21.
• Gilbertson M. K., Hafner G. D., Drouillard K. G., Albert A., Dixon B., Immunosupression in the Northern leopard frog (Rana pipiens) induced by pesticide exposure, „Environmental Toxicology & Chemistry” 2003, nr 22.
• Governa M., Valentiono M., Visona I., In vitro impairment of human granulocyte functions by lead, „Archives of Toxicology” 1987, nr 6.
• Gurer H., Ercal N., Can antioxidants be beneficial in the treatment of lead poisoning?, „Free Radical Biology & Medicine” 2000, nr 29.
• Hadji-Azimi I., Coosemans V., Canicatti C., Atlas of adult Xenopus laevis laevis hematology, „Developmental & Comparative Immunology” 1987, nr 11.
• Haywood L. K., Alexander G. J., Byrne M. J., Cukrowska E., Xenopus laevis embryos and tadpoles as models for testing for pollution by zinc, copper, lead and cadmium, „African Zoology” 2004, nr 39.
• Houlahan J. E., Findlay C. S., Schmidt B. R., Meyer A. H., Kuzmin S. L., Quantitative evidence for global amphibian population declines, „Nature” 2000, nr 404.
• Ireland M. P., Lead retention in toads Xenopus laevis fed increasing levels of leadcontaminated earthworms, „Environmental Pollution” 1977, nr 12.
• Jeremin B., Bogdanowicz B. Wpływ ołowiu na stan i funkcję układu odpornościowego, „Wiadomości Lekarskie” 1991, nr 44 (3/4).
• Jurd R. D., A natural heterohaemagglutinin in Xenopus laevis serum, „Immunology” 1987, nr 34.
• Kowalak A., Metale śmierci, Centrum Edukacji Ekologicznej Wsi, Krosno 1991
• Linder G., Grillitsch B., Ecotoxicology of metals, [w:] Environmental of amphibian and reptiles, eds. D. W. Sparling, G. Linder, C. A. Bishop, Pensacola 2000, s. 325–459
• Lombourdis N. S., Wray D., Heavy-metal concentration in the frog Rana ridibunda from a small river of Macedonia, Northern Greece, „Environmental International” 1998, nr 24.
• Mann R., Bidwell J., Toxicological issues for amphibians in Australia, [w:] Declines and Disappearances of Australian Frogs, ed. A. Campbell, Canberra 1999, s. 185–201.
• Martynowicz H., Andrzejak R., Mędraś M., Wpływ ołowiu na funkcje gonad męskich, „Medycyna Pracy” 2005, nr 56.
• McCabe M. J., Lead, [w:] Immunotoxicology of Environment and Occupational Metals, eds. J. T. Zelikoff, P. T. Thomas, London 1998, s. 111–129
• . McCabe M. J., Lawrence D. A., The heavy metal lead exhibits B cell-stimulatory factor by enhancing B cell Ia expression and differentiation, „Journal of Immunology” 1990, nr 145.
• Mulvey M., Diamond S. A., Genetic factor and tolerance acquisition in population exposed to metals and metalloids, [w:] Metal Ecotoxicology. Concepts and Applications, eds. M. C. Newman, A. W. McIntosh, Chelsea (Michigan) 1991, s. 301–321.
• . Newman M. C., Unger M. A., Fundaments of Ecotoxicology, Boca Raton 2003.
• . Patric L., Lead toxicity, a review of the literature. Part I: exposure, evaluation and treatment, „Alternative Medicine Review” 2006, nr 11.
• Patric L., Lead Toxicity Part II: The role of free radical damage and the use of antioxidants in pathology and treatment of lead toxicity, „Alternative Medicine Review” 2006, nr 11.
• Perí S. I., Fink N. E., Salibián A., Hematological parameters in Bufo arenarum injected with subletal dose of Pb acetate, „Biomedical and Environmental Sciences” 1998, nr 11.
• . Quig D., Cysteine Metabolism and Metal Toxicity, „Alternative Medicine Review” 1998, nr 3.
• . Raghavan S. R. V., Culver B. C., Gonik C., Erythrocyte lead-binding protein after occupational exposure, „Environmental Research” 1980, nr 22
• Rollins-Smith L. A., Hopkins B. D., Reinert L. K., An amphibian model to test effect of xenobiotic chemicals on development of the hematopoietic system, „Environmental Toxicology & Chemistry” 2004, nr 23.
• Rosenberg C. E., Per S. I., Arrieta M. A., Fink N. E., Salibián A., Red blood cell osmotic fragility in Bufo arenarum exposed to Pb, „Archives of Physiology and Biochemistry” 1998, nr 106.
• 5. Rosenberg C. E., Fink N. E., Arrieta M. A., Salibián A., Effect of lead acetate on the in vitro engulfment and killing capability of the toad (Bufo arenarum) neutrophils, „Comparative Biochemistry and Physiology” 2003, nr 136C.
• Rowe C. L., Hopkins W. A., Coffman V. R., Failed recruitment of Southern toads (Bufo terrestris) in trace element-contaminated breeding habitat: direct and indirect effect that may lead to a local population sink, „Archives of Environmental Contamination and Toxicology” 2003, nr 40..
• . Schluter S. F., Bernstein R. M., Marchalonis J. J., Molecular origins ad evolution of immunoglobulin heavy-chain genes of jawed verterbrates, „Immunology Today” 1997, nr 18.
• Sharma S. S., Dietz K. J., The relationship between metal toxicity and cellular redox imbalance, „Trends in Plant Science” 2009, nr 14.
• Skoczyńska A., Poręba R., Sieradzki A., Andrzejak R., Sieradzka U., Wpływ ołowiu i kadmu na funkcje układu immunologicznego, „Medycyna Pracy” 2002, nr 53.
• 0. Sobotka J. M., Radwan R. G., Teratogenesis induced by short – and long-term exposure of Xenopus laevis progeny to lead, „Journal of Toxicology and Environmental Health” 1995, nr 44.
• Steele C. W., Stickler-Shaw S., Taylor D. H., Failure of Bufo americanus tadpoles to avoid lead-enriched water, „Journal of Herpetology” 1991, nr 25.
• Stohs, S. J., Bagchi, D., Oxidative mechanism in the toxicity of metal ions, „Free Radial Biology & Medicine” 1995, nr 18.
• Szubarkowska E., Gromysz-Kalkowska K., Wójcik K., Behavior of the fordem blond elements in Rana esculenta after repeated contacts of the animals with a therapeutic dose of foschlor, „Bulletin of Environmental Contamination and Toxicology” 1990, nr 45.
• Valko M., Morris H., Cronin M. T., Metals, toxicity and oxidative stress, „Current Medicinal Chemistry” 2005, nr 12.
• Varela M. E., Sellarés M. E., Sobre la morfología hemática de Bufo arenarum (Hensel), „Review of Society Argent Biology” 1937, nr 13.
• Wahedi M. Heavy metals-induced autoimmunity: a possible role for lead, „Central European Journal of Immunology” 2000, nr 25
• Williams G. M., Iatropoulos M. J., Alteration of liver cell function and proliferation: differentiation between adaptation and toxicity, „Toxicologic Pathology” 2002, nr 30.
• Yeung G. L., The influence of lead and environmental pollutants on metamorphosis of Rana urticularia (Amphibia: Ranidae), „Proc. Ark. Academic Society” 1978, nr 32.
• Zapata A. G., Varas A., Torroba M., Seasonal variations in the immunoe system of lower verterbrates, „Immunology Today” 1992, nr 13.

• Document Type: undetermined