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2021 | 160 | 111-123
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Elemental, proximate and phytochemical evaluation of Phyllanthus muellerianus (Kuntze) Excell leaves

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EN
Phyllanthus muellerianus (Kuntze) Excell (Euphobiaceae) is a popular member of genus “Phyllanthus” in Africa. The use of herbal remedies has been largely employed for the management and treatment of some health challenges and diseased conditions which has led to the experiment on Phyllanthus muellerianus leaves. The objective of the study is to evaluate the nutritional characteristics which includes the mineral content, proximate, as well as the phytochemicals present in the leaves of this plant. The plant part studied was examined for the minerals, proximate and phytochemical components present in them using standard laboratory techniques. Screening of the elemental content using Atomic Absorption Spectrophotometer showed the presence of Magnesium (Mg) (3157.50 mg/kg), Manganese (Mn) (189.50 mg/kg), Iron (Fe) (122.00 mg/kg), Copper (Cu) (10.30 mg/kg), Zinc (Zn) (28.50 mg/kg), however, elements Chromium (Cr), Nickel (Ni), Cobalt (Co) and toxic elements Lead (Pb) and Cadmium (Cd) were found absent. Proximate components such as moisture content (9.58%), fat (2.40%), crude protein (23.42%), crude fibre (13.39%) and ash (7.67%) were also found present. Phytochemical screening revealed the presence of tannins, saponins, alkaloids, flavonoids and terpenoids while cardiac glycosides, terpenoids and steroids were found absent. The results obtained from this study indicates that there are essential nutritional and phytochemical components in the leaves which are beneficial and could complement protein and mineral deficiencies and which could also serve as a lead in the quality and safety assurance of this plant.
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Volume
160
Pages
111-123
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Contributors
author
  • Bio-medicinal Research Centre, Forestry Research Institute of Nigeria, P.M.B 5054, Jericho Hills, Ibadan, Oyo State, Nigeria
author
  • Bio-medicinal Research Centre, Forestry Research Institute of Nigeria, P.M.B 5054, Jericho Hills, Ibadan, Oyo State, Nigeria
author
  • Bio-medicinal Research Centre, Forestry Research Institute of Nigeria, P.M.B 5054, Jericho Hills, Ibadan, Oyo State, Nigeria
  • Bio-medicinal Research Centre, Forestry Research Institute of Nigeria, P.M.B 5054, Jericho Hills, Ibadan, Oyo State, Nigeria
author
  • Bio-medicinal Research Centre, Forestry Research Institute of Nigeria, P.M.B 5054, Jericho Hills, Ibadan, Oyo State, Nigeria
References
  • [1] Boakye, Y.D; Agyare, C; Abotsi, W.K.M; Ayande, P.G; Ossei, P.P.M. (2016). Anti-inflammatory activity of aqueous leaf extract of Phyllanthus muellerianus (Kuntze) Exell and its major constituent, geraniin. Journal of Ethnopharmacology. 187: 17-27
  • [2] WHO, (2004). WHO Guidelines on Safety Monitoring of Herbal Medicines in Pharmacovigilance Systems. Geneva, Switzerland: World Health Organization.
  • [3] Hostettman, K &Terreaux, C. (2000). Search for new lead compounds from higher plants. CHIMIA International Journal of Chemistry. 54: 652-657
  • [4] Prasad, A.K; Kumar, V; Arya, P; Kumar, S; Dabur, R; Singh, N; Parmar, V.S. (2005). Investigations towards new lead compounds from medicinally important plants. Pure Appl. Chem. 77: 25-40
  • [5] Zhang, X; Chen, L.X; Ouyang, L; Cheng, Y; Liu, B. (2012). Plant natural compounds: targeting pathways of autophagy as anti-cancer therapeutic agents. Cell Prolif. 45: 466-476
  • [6] Doughari, J.H; Sunday, D. (2008). Antibacterial Activity of Phyllanthus muellerianus. Journal of Pharmaceutical Biology. 46(6):400-405
  • [7] Burkill, H. M. (1994). The useful plants of West Tropical Africa. Royal Botanical Gardens, Kew
  • [8] Adedapo, A.A., Abatan, M.O., Olorunsogo, O.O. (2007). Effects of some plants of thespurge family on haematological and biochemical parameters in rats. Veterinary Arhive 77: 29-38
  • [9] Katsayal, U.A; Lamai, R.S. (2009). Preliminary Phytochemical and Antibacterial screening of the Ethanolic stem bark extract of P. muellerianus. Nigerian Journal of Pharmaceutical Sciences. Vol 8 (2): 121-125
  • [10] Kone, M.W., KamanziAtindehou, K., Terreaux, C., Hostettmann, K., Traore, D., Dosso, M. (2004). Traditional medicine in North Côte d’Ivoire: screening of 50 medicinal plants for antibacterial activity. Journal of Ethnopharmacology. 93: 43-49
  • [11] Assob, C.N., Kamga, L.F., Nsagha, D.S., Njunda, A.L., Nde, P.F., Asongalem, E.A., Njouendou, A.J., Sandjon, B., Penlap, V.B. (2011). Antimicrobial and toxicological activities of five medicinal plant species from Cameroon Traditional Medicine. BMC Complementary and Alternative Medicine 11: 70
  • [12] Brusotti, G; Cesari, L; Gilardoni, G; Tosi, S; Grisoli, P; Picco, A.M; Caccialanza. (2012). Chemical composition and antimicrobial activity of Phyllanthus muellerianus (Kuntze) Excel essential oil. Journal of Ethnopharmacology. 142: 657-662
  • [13] Zirihi, G.H; Mambu, L; Guede-Guina, F; Bodo, B; Grellier, P. (2005). In vitro antiplasmodial activity and cytotoxicity of 33 West African plants used for treatment of malaria. Journal of Ethnopharmacology 98 (3): 281-285
  • [14] Ndjonka, D; Bergmann, B; Agyare, C. (2012). In vitro activity of extracts and isolated polyphenols from West African Medicinal plants against Plasmodium falciparum. Parasitology Research 111 (2): 827-834.
  • [15] Agyare, C; Lechtenberg, M; Deters, A; Petereit, F; Hensel, A. (2011). Ellagitannins from Phyllanthus muellerianus (Kuntze) Exell: Geraniin and furosin stimulate cellular activity, differentiation and collagen synthesis of human skin keratinocytes and dermal fibroplasts. Phtomedicine. 18(7): 617-624
  • [16] Saleem, M; Nazir, M; Akhtar, N. (2009). New phthalates from Phyllanthusmuellerianus (Euphorbiaceae). Journal of Asian Natural Products Research 11(11): 974-977
  • [17] Mao, X; Wu, L.F; Guo, H.L; Chen, W.J; Cui, Y.P; Qi, Q; Li, S; Liang, W.Y; Guang-Hui, Y; Yan-Yan, Shao; Dan, Z; Gai-Mei, S; Yun, Y; Zhang, L.Z. (2016). The Genus Phyllanthus: An Ethnopharmacological, Phytochemical, and Pharmacological Review. Evidence Based Complementary and Alternative Medicine 20: 1-36
  • [18] WHO, (2002b). Traditional Medicine Strategy (2002b). WHO/EDM/TRM/2002.1.Geneva, Switzerland: World Health Organization
  • [19] Trease, G.E; Evans, W.C., (2002). Pharmacognosy.15th Edition. Saunders Publishers.
  • [20] Evans, W.C. 2002. Trease and Evans Pharmacognosy, (15th Edition), W.B. Saunders Company Ltd., London, Pp. 191-393
  • [21] AOAC. (2005). Official Methods of Analysis. 18th Edition. Association of Official Analytical Chemists, Washington, DC., USA.
  • [22] Isaac, A.R. &Korber, J.D. (1971). Atomic absorption and flame photometry Technique and uses in soil, plant and water analysis. In L.M. Walsh (Ed) Instrumental Methods for analysis of soils, and plant tissues. Soil Science Society America Incorporation Wisconsin USA.
  • [23] Ekor, M. (2014). The growing use of herbal medicines: Issues relating to adverse reactions and challenges in monitoring safety. Frontiers in Pharmacology 4(177): 1-10
  • [24] Awotedu, O.L and Ogunbamowo, P.O. (2019). Nutritional, Anti-Nutritional and Phytochemical Profile of the Leaves and Fruits of Synsepalum dulcificum (Schumach. & Thonn.) Daniell. American Journal of Biological Chemistry 7(3): 53-59
  • [25] Odewale, M.O and Lawal, I.O. (2017). Nutrient Characterization and Proximate Analysis of Carbonized, Non-carbonized Vermicast (Earthworm cast) as a Potential Remedy for Some Ailments in Nigeria. Nigerian Journal of Natural Products and Medicine, Vol 21, pp 1-4
  • [26] Umoh, E.D; Akpabio, U.D; Udo, I.E. (2013). Phytochemical screening and nutrient analysis of Phyllanthus amarus. Asian Journal of Plant Science and Research. 3(4): 116-122
  • [27] Omolola, T.O. 2020. Phytochemical, Proximate and Elemental Composition of Tithonia diversifolia (Hemsley) A.Gray leaves. International Annals of Science 8(1): 54-61
  • [28] Takeri, H; Einar, B; Hanffen, H. 2004. Pharmaceutical analysis. CBS Publishers Distributors India.
  • [29] James, O; Friday, E.T. 2010. Proximate and Nutrient Composition of Euphorbia heterophylla: A medicinal plant from Anyigba, Nigeria. Journal of Medicinal Plants Research. 4(14): 1428-1431
  • [30] Ghosh, P and Chatterjee, S. 2020. Evaluation of Organoleptic, Proximate parameters and Analysis of Nutritional Composition of Five wild weeds: A search for low cost nutraceuticals. International Journal of Pharmaceutical Science & Research 11(10): 5170-81
  • [31] Igwenyi, I; Agwor, A; Nwigboji, I; Agbafor, Kingsley; Offor, C. 2014. Proximate Analysis, Mineral and Phytochemical Composition of Euphorbia Hyssopifolia. Journal of Dental and Medical Sciences 13(6): 41-43
  • [32] Bonde, J.P. &Apostoli, P. (2004). Any need to revisit the male reproductive toxicity of Lead? Occupational and Environmental Medicine 62(1): 1-2
  • [33] Meeker, J.D., M.G. Rossano, B. Protas, M.P. Diamond, E. Pusheck, D. Daly, N. Paneth, J.J. Wirth. (2008). Cadmium, Lead, and other metals in relation to semen quality: human evidence for molybdenum as a male reproductive toxicant. Environ Health Perspect 116(11): 1473-1479
  • [34] Telisman, S; B. Colak, A. Pizent, J. Jurasovic, P. Cvitkovic (2007). Reproductive Toxicity of low-level lead exposure in men. Environmental Research 105 (2): 255-266
  • [35] Okiki Pius A., Olatunji Babawale P., Egbebi Adebimpe Asoso Sola and Ojo Comfort. 2015. A Comparative Study of Nutritional and Phytochemical Composition of Phyllanthus amarus Leaf and Seed. American-Eurasian Journal of Toxicological Sciences 7 (4): 321-327
  • [36] British Pharmacopoeia. (1980). Can Med Assoc J. 126 (5):514-515
  • [37] Voet, D.J., Voet, J.G., Pratt, C.W. (2008). The Principles of Biochemistry. 3rd Edition. John Wiley & Sons, 111 River Street, Hoboken, pp 74-219.
  • [38] Egbon, E.E, Olayioye, E.Y, Olayioye S.A, Adesuyi, A.T, Owolabi, T. 2017. Phytochemical screening and Proximate composition of Phyllanthus amarus. International Research Journal of Plant Science 8(1): 009-012
  • [39] Okeke, C.U; Adaku, C.N. (2009). Phytochemical and Proximate Analysis of Euphorbia heterophylla Linn. (Euphorbiaceae). Nigerian Journal of Botany. 22(1):215-222
  • [40] Olalekan, O.J; Apenah, M.O; Ogunbela, A.A; Elumalero, G.O and Agboola, J.O. (2020). Evaluation of the Phytochemical, Antioxidant and Nutritional Properties of Phyllanthus muellerianus Leaves. Journal of Research in Forestry, Wildlife & Environment 12(4): 142-149
  • [41] African Pharmacopopeia. (1986). Dou/Strc. Scientific Publication. Pp. 140-150.
  • [42] Guisseppe, R. &Baratta, T.M. (2000). Antioxidant activity of selected essential oil components in two lipid model systems. African Journal of Biotechnology 69(2): 167-174
  • [43] Pamela, C.C; Richard, A.H; Denise, R.F. (2005). Lippincott’s illustrated reviews biochemistry. 3rd ed., Lippincott Williams and Wilkins, Philadelphia. pp. 335-388
  • [44] Edeoga, H. O., Eriata, D. O. Alkaloid, tannin and saponin contents of some medicinal plants. Journal of Medicinal Aromatic Plant Science 2001; 23(3): 344-349
  • [45] Menta, K; Patel, B.N; Jain, B.K. (2013). Phytochemical analysis of leaf extract of Phyllanthus fraternus. Research Journal of Recent Sciences 2: 12-15
  • [46] Obianimi, A.W; Uche, F.I. (2008). The Phytochemical screening and the effects of methanolic extract of Phyllanthus amarus leaf on the Biochemical parameters of male Guinea pigs. Journal of Applied Science and Environmental Management 12(4): 73-77
  • [47] Norton BW. The significance of tannins in tropical animal production. Tannins in livestock and human nutrition. ACIAR Proceedings 2000; 92: 14-22
  • [48] Akiyama H, Kazuyasu F, Yamasaki O, Oono T, Iwatsuki K. Antibacterial action of several tannins against Staphylococcus aureus. Journal of Antimicrobial Chemotherapy 2001; 48: 487‐491
  • [49] Kolodziej H, Kiderlen AF. Antileishmanial activity and immune modulatory effects of tannins and related compounds on Leishmania parasitised RAW 264.7 cells. Phytochemistry 2005; 66: 2056-2071
  • [50] Okwu DE. Phytochemicals and vitamin content of indigenous spices of South-eastern Nigeria. Journal of Sustainable Agriculture and Environment. 2004; 6: 30-34
  • [51] Shrinjana Dhar, Kaushik Gupta, Soumendra Nath Talapatra, QSAR modeling for prediction of acute toxicity and mutagenicity in different test models by established common phytochemicals present in Phyllanthus niruri. World Scientific News 37 (2016) 202-219
  • [52] F. S. Nworie, W. O. Oti, U. Nwali, Modeling and analysis of batch extraction process for efficient removal of cadmium and pathogens from aqueous solution using modified plantain peel biochar. World Scientific News 157 (2021) 1-24
  • [53] Chinyere B. C. Ikpa, Tochukwu D. O. Maduka, Chinomnso Uzoamaka Ikpa, Evaluation of phytochemical composition and in vitro antioxidant potential of Cyathea latebrosa leaves World Scientific News 157 (2021) 25-37
  • [54] Aborode Abdullahi Tunde, Adegble Victor Adesewa, Phytochemical Profile and Antioxidant Potential of Rind Essential Oil of Citrus reticulate Blanco. World Scientific News 145 (2020) 366-378
  • [55] P. C. Nnaji, C. C. Okoye, J. U. Umeuzuegbu, Efficiency evaluation of Luffa cylindrica and Mucuna sloanei seeds in dye removal: A news approach World Scientific News 146 (2020) 184-201
  • [56] Paula-Peace O. James-Okoro, Franklyn N. Iheagwam, Mariam I. Sholeye, Itoroobong A. Umoren, Babatunde O. Adetuyi, Adebanke E. Ogundipe, Adefoyeke A. Braimah, Tobi S. Adekunbi, Oluseyi E. Ogunlana, Olubanke O. Ogunlana, Phytochemical and in vitro antioxidant assessment of Yoyo bitters World News of Natural Sciences 37 (2021) 1-17
  • [57] R. U. B. Ebana, U. O. Edet, K. I. Anosike, C. A. Etok, T. O. Kanu, Nutritional analysis and wine production potentials of Telfairia occidentalis (fluted pumpkin) leaves and Cucumis sativus L. (cucumber) using Baker’s and palm wine yeast strains World News of Natural Sciences 22 (2019) 12-30
  • [58] Ghoshal S, Krishna BN, Lakshmi V. Antiamoebic activity of piper longum fruits against Entamoeba histolytica in vito and in vivo. Journal of Ethnopharmacology. 1996; 50: 167-170.
  • [59] Okwu, D. E, IN Emenike. Evaluation of the phyto-nutrients and vitamins content of the citrus fruits. International Journal of Molecular Medicine and Advance Science 2006; 2(1): 1-6
  • [60] Bunt M, F Bucar. Antioxidant activity of Nigella sativa essential oils. Phytochemistry 2000; 57: 99-102
  • [61] Mahato SB, Sen S. Advances in triterpenoid research. Phytochemistry 1997; 44: 1185-1236
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article
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bwmeta1.element.psjd-768f1ee6-ab28-49ed-8930-e6a45094d4e0
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