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2017 | 20 | 3 | 7-11
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Stress as an environmnetal risk factor for autoimmune diseases

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Stres jako środowiskowy czynnik ryzyka chorób autoimmunologicznych
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Stress is considered to be both a trigger of autoimmune diseases and a factor which contributes to disease exacerbation. Emotional stress before the disease onset is reported by up to 80% of patients suffering from autoaggressive diseases. A significant increase in the prevalence of autoimmune diseases in recent years and the growing number of stressors in our daily lives, including the work environment, raise a question about a link between psychological stress and autoimmune disorders. Therefore, the objective of this paper is to highlight the potential role of stress in both development and exacerbation of autoimmune diseases. The potential mechanisms by which stress can affect autoimmunity are characterised. In particular, the focus is on rheumatic diseases, autoimmune endocrine disorders, multiple sclerosis, and psoriasis. In addition, the role of post-traumatic stress disorder is underlined, as well as the possible association between stress present in the work environment and the development of autoimmune diseases among employees.
Stres jest uważany zarówno za czynnik spustowy dla chorób autoimmunologicznych jak i przyczyniający się do ich zaostrzenia. Stres emocjonalny, występujący przed pojawieniem się choroby, zgłasza nawet do 80% pacjentów cierpiących na choroby z autoagresji. Znaczący wzrost zachorowalności na choroby autoimmunologiczne oraz rosnąca liczba czynników stresogennych w naszym codziennym życiu, w tym w środowisku pracy, stawia pytanie o związek pomiędzy stresem psychicznym a chorobami autoimmunologicznymi. Dlatego też celem artykułu jest naświetlenie możliwej roli stresu w rozwoju i zaostrzeniach chorób autoimmunologicznych. Scharakteryzowano potencjalne mechanizmy, za pomocą których stres może oddziaływać na autoimmunizację. W szczególności skupiono się na chorobach reumatologicznych, zaburzeniach endokrynologicznych, stwardnieniu rozsianym oraz łuszczycy. Dodatkowo podkreślono rolę stresu pourazowego jak i możliwych związków pomiędzy stresem w środowisku pracy a rozwojem chorób autoimmunologicznych wśród pracowników.
  • Department of Hygiene, Wroclaw Medical University, Wrocław
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