Preferences help
enabled [disable] Abstract
Number of results
2016 | 13 | 1 | 65-71
Article title

Endocrine Responses to Physical Training and Tribulus Terrestris Supplememtation in Middle-Age Men

Title variants
Languages of publication
The aim of this study was to evaluate the effects of steroidal saponin supplementation on blood concentration of T, GH and IGF-1. The research involved 14 men between the age of 45 and 60 years. The duration of the experiment was 12 weeks. There were two series of laboratory tests. Independent tests were conducted at the beginning and after 12 weeks of the intervention. A two-way repeated measures ANOVA revealed a statistically significant effect of the intervention on the following variables: T-Ch (η2 = 0.542), HDL-Ch (η2 = 0.522), LDL-Ch (η2 = 0.587), T (η2 = 0.603), IGF-1 (η2 = 0.512) and GH (η2 = 0.621). Thus, FFM significantly increased while TBF and BM decreased in comparison to pre-intervention levels. The analyzed results indicate that treatment or supplementation of individual hormone deficiencies can be a successful form of counteracting the aging process. Nevertheless, the effects of TT supplementation on the concentration of T as well as GH and IGF-1, requires further studies, especially in middle-aged and older subjects, along with different exercise programs. The analyzed results indicate that treatment or supplementation of individual hormone deficiencies can be a major form of counteracting the aging process.
  • Adimoelja, A.(2000). Phytochemicals and the breakthrough of traditional herbs in the management of sexual dysfunctions. Int J Androl, 23 (2), 82–84.
  • Amore, M. (2005). Partial androgen deficiency and neuropsychiatric symptoms in aging men. J. Endocrinol Invest, 28, 49–54.
  • Antonio, J., Uelmen, J., Rodriguez, R., Earnest, C. (2010). The effects of Tribulus terrestris on body composition and exercise performance in resistance-trained males. Int. J. Sport Nutr. Metab, 10, 208–215.
  • Bird, S.P., Tarpenning, K.M., Marino, F.E. (2006). Effects of liquid carbohydrate/essential amino acid ingestion on acute hormonal response during a single bout of resistance exercise in untrained men. Nutrition, 22 (4), 367–375.
  • Blackman, M.R., Sorkin, J.D., Munzer, T., Bellantoni, M.F., Busby-Whitehead, J., Stevens, T.E., Jayme, J., O’Connor, K.G., Christmas, C., Tobin, J.D., Stewart, K.J., Cottrell, E., St. Clair, C., Pabst, K.M., Harman, S.M. (2002). Growth hormone and sex steroid administration in healthy aged women and men: a randomized controlled trial. JAMA, 288, 2282–2292.
  • Brown, G.A., Vukovich, M.D., Martini, E.R., Kohut, M.L., Franke, W.D., Jackson, D.A., King, D.S. (2001). Endocrine and lipid responses to chronic androstenediol-herbal supplementation in 30 to 58 year old men. J Am Coll Nutr, 20, 520–528.
  • De Combarieu, E., Fizzati, N., Lovati, M., Mercalli, E. (2003). Furostanol saponins from Tribulus terrestris. Fitoterapia, 74 (6), 583–591.
  • Gauthaman, K., Mohamed Saleem, T.S., Ravi, V., Sita, P.S., Niranjali, D.S. (2008). Alcoholic Extract of Terminalia Arjuna Protects Rabbit Heart against Ischemic-Reperfusion Injury, Role of Antioxidant Enzymes and Heat Shock Protein. World Acad. Sci. Engineer. Technol, 18, 488–498.
  • Hare, D.J., Lei P., Ayton, S., Roberts, B.R., Grimm, R., George, J.L., Bishop, D., Beavis, A., Donovan, S.J., McColl, G., Volitakis, I., Masters, C.L., Adlard, P.A., Cherny, R.A., Bush, A.I., Finkelstein, D.I., Doble, P. (2014). An iron–dopamine index predicts risk of parkinsonian neurodegeneration in the substantia nigra pars compacta. Chem. Sci, 5, 2160–2169.
  • Hopkins, W.G. (2010). Linear Models and Effect Magnitudes for Research, Clinical and Practical Applications. Sportscience, 14, 49–57.
  • Huang, J.W., Tan Jiang, S.H., Zhu, D.Y. (2003).Terrestrinins A and B, two new steroid saponins from Tribulus terrestris. J Asian Nat Prod Res, 10, 285–290.
  • Milasius, K., Dadeliene, R., Skernevicius, J. (2009). The influence of the Tribulus terrestris extract on the parameters of the functional preparedness and athletes’ organism homeostasis. Fiziol Zh, 55: 89–96.
  • Munzer, T., Harman, S.M., Sorkin, J.D., Blackman, M.R. (2009). Growth hormone and sex steroid effects on serum glucose, insulin, and lipid concentrations in healthy older women and men. J Clin Endocrinol Metab, 94 (10), 3833–3841.
  • Neychev, V.K., Mitev, V.I. (2005).The aphrodisiac herb Tribulus terrestris does not influence the androgen production in young men. J Ethnopharmacol, 101 (1–3), 319–323.
  • Poole, C., Bushey, B., Foster, C., Campbell, B., Willoughby, D., Kreider, R., Taylor, L., Wilborn, C. (2010). The effects of a commercially available botanical supplement on strength, body composition, power output, and hormonal profiles in resistance-trained males. J Int Soc. Sport Nutr, 7, 34.
  • Poprzecki, S., Zebrowska, A., Cholewa, J., Zając, A., Waskiewicz, Z. (2005). Ergogenic effects of Tribulus Terrestris supplementation in men. J Hum Kin, 13, 41–50.
  • Rogerson, S., Riches, C.J., Jennings, C. Weatherby, R.P., Meir, R.A., Marshall-Gradisnik, S.M. (2007). The effect of five weeks of tribulus terretris suplementation on muscle strength and body composition during preseason training in elite rugby league players. J Strength Cond Res, 21 (2), 348–353.
  • Zając, A., Czuba, M., Poprzecki, S., Waśkiewicz, Z., Cholewa, J., Pilch, J., Chycki, J. (2010). Effects of Growth Hormone Therapy and Physical Exercise on Anaerobic and Aerobic Power, Body Composition, Lipoprotein Profile in Middle Aged Men. J Hum Kin, 25, 67–76.
  • Zając, A., Wilk, M., Socha, T., Maszczyk, A., Chycki, J. (2014). Effects of growth hormone and testosterone therapy on aerobic and anaerobic fitness, body composition and lipoprotein profile in middle-aged men. Ann Agric Environ Med, 21 (1), 175–171.
Document Type
Publication order reference
YADDA identifier
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.