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2022 | 44 | 1-23

Article title

Effect of Monosodium Glutamate on the Body System

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EN

Abstracts

EN
Worldwide, monosodium glutamate is utilized as a flavor enhancer and is composed of essential amino acids for nutrition. Numerous health issues are thought to be linked to monosodium glutamate. Studies have demonstrated that monosodium glutamate has harmful side effects, notably in animals, such as the development of obesity and diabetes as well as hepatotoxic, neurotoxic, and genotoxic consequences. According to several accounts, human subjects were becoming more ravenous, eating more, and becoming obese. Only a few human studies have been done to examine the potential genotoxic, neurotoxic, and hepatotoxic consequences of monosodium glutamate. Exploring the molecular and metabolic mechanisms relating to monosodium glutamate will need a lot of investigation.

Year

Volume

44

Pages

1-23

Physical description

Contributors

  • Department of Natural Sciences, Faculty of Pure and Applied Sciences, Precious Cornerstone University, Ibadan, Oyo State, Nigeria
  • Department of Natural Sciences, Faculty of Pure and Applied Sciences, Precious Cornerstone University, Ibadan, Oyo State, Nigeria
  • Department of Natural Sciences, Faculty of Pure and Applied Sciences, Precious Cornerstone University, Ibadan, Oyo State, Nigeria
  • Department of Natural Sciences, Faculty of Pure and Applied Sciences, Precious Cornerstone University, Ibadan, Oyo State, Nigeria
  • Department of Natural Sciences, Faculty of Pure and Applied Sciences, Precious Cornerstone University, Ibadan, Oyo State, Nigeria
  • Department of Natural Sciences, Faculty of Pure and Applied Sciences, Precious Cornerstone University, Ibadan, Oyo State, Nigeria

References

  • [1] Giacometti, T. Free and bound glutamate in natural products. In: Glutamic Acid: Advances in Biochemistry (Filer, L.J., Garattini, S., Kare, M.R., Reynolds, W.A. and Wurtman, R.J., eds), Raven Press, New York, NY, (1979) pp 25 – 34.
  • [2] JECFA. L-glutamic acid and its ammonium, calcium, monosodium and potassium salts. In: Toxicological Evaluation of Certain Food Additives and Contaminants. New York, Cambridge University Press, (1988) pp 97 – 161
  • [3] FASEB. Analysis of Adverse Reactions to Monosodium Glutamate (MSG), Report, Life Sciences Research Office, Federation of American Societies for Experimental Biology, Washington, DC (1995).
  • [4] N Munir, M Hasnain, H Waqif, BO Adetuyi, C Egbuna, MC Olisah. Gelling Agents, Micro and Nanogels in Food System Applications. Application of Nanotechnology in Food Science, Processing and Packaging, (2022) 153-167
  • [5] Abramson, M.J., Kutin, J.J. and Bowes, G. The prevalence of asthma in Victorian adults. Aust. NZ. J. Med. 22 (1992) 358-363
  • [6] Robertson, C.F. Prevalence of asthma in Melbourne schoolchildren: changes over 26 years. Br. Med. J. 302 (1991) 1116-1118
  • [7] Woods, D., Parry, D., Cherwinski, H., Bosch, E., Lees, E., & McMahon, M. Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1. Molecular and cellular biology, 17(9) (1997) 5598-5611
  • [8] O’Byrne, P.M. Leukotrienes in the pathogenesis of asthma. Chest 111(Suppl.) (1997) 27S – 34S
  • [9] Stevenson, D.D. Monosodium glutamate and asthma. In: International Symposium on Glutamate, Proceedings of the symposium held October, 1998 in Bergami. Italy. J. Nutr. 130 (Suppl) (2000) 1067S-1073S
  • [10] Allen, D.H. and Baker, G.J. Chinese restaurant asthma [Letter]. New Engl. J. Med. 278 (1981) 796
  • [11] Germano, P., Cohen, S.G., Hahn, B. and Metcalfe, D.D. An evaluation of clinical reactions to monosodium glutamate (MSG) in asthmatics, using a blinded placebo-controlled challenge. J. Allergy Clin. Immunol. 87 (1991) 177
  • [12] Altman, D.R., Fitzgerald, T. and Chiaramonte, L.T. Double-blind placebo-controlled challenge (DBPCC) of persons reporting adverse reactions to monosodium glutamate (MSG). J. Allergy Clin. Immunol. 93 (1994) 303
  • [13] Schwartzstein, R. Kelleher, M., Weinberger, S., Weiss, J. and Drazen, J. Airway effects of monosodium glutamate in subjects with chronic stable asthma. J. Asthma 24 (1987) 167-172
  • [14] Woessner, K. M., Simon, R. A., & Stevenson, D. D. Monosodium glutamate sensitivity in asthma. Journal of allergy and clinical immunology, 104(2) (1999) 305-310
  • [15] Allen, D.H., Delohery, J. and Baker, G. Monosodium L-glutamate-induced asthma. J. Allergy Clin. Immunol. 80 (1987) 530-537
  • [16] Moneret-Vautrin, D.A. Monosodium glutamate induced asthma: a study of the potential risk in 30 asthmatics and review of the literature. Allerg. Immunol. 19 (1987) 29-35
  • [17] Hodge, L., Yan, K.Y. and Loblay, R.L. Assessment of food chemical intolerance in adult asthmatic subjects. Thorax 51 (1996) 805-809
  • [18] Sampson, H.A. and Burks, A.W. Mechanisms of food allergy. Ann. Rev. Nut. 16 (1996) 161-177
  • [19] Metcalfe, D.D., Astwood, J.D., Townsend, R., Sampson, H.A., Taylor, S.L. and Fuchs, R.L. Assessment of the allergenic potential of foods derived from genetically engineered crop pants. Crit. Rev. Food Sci. Nut. 36(S) (1996) S165-S186
  • [20] Adetuyi B.O, Oluwole E.O Dairo J.O. Chemoprotective Potential of Ethanol Extract of Ganoderma Lucidum on Liver and Kidney Parameters in Plasmodium Beghei-Induced Mice. International Journal of Chemistry and Chemical Processes 1(8) (2015) 29-36
  • [21] Sampson, H.A. Immunologic mechanisms in adverse reactions to foods. Immunology and Allergy Clinics of North America. 11 (1990b) 701-706
  • [22] Burks, A.W. and Sampson, H. Food allergies in children. Curr. Prob. Paed. 23 (1993) 230-252
  • [23] BO Adetuyi, GO Odine, PA Olajide, OA Adetuyi, OO Atanda, JK Oloke. Nutraceuticals: role in metabolic disease, prevention and treatment. World News of Natural Sciences 42 (2022) 1-27
  • [24] Adetuyi B.O, Oluwole E.O, Dairo J.O. Biochemical effects of shea butter and groundnut oils on white albino rats. International Journal of Chemistry and Chemical Processes 1(8) (2015) 1-17
  • [25] Taylor, S. E., Klein, L. C., Lewis, B. P., Gruenewald, T. L., Gurung, R. A., & Updegraff, J. A. Biobehavioral responses to stress in females: tend-and-befriend, not fight-or-flight. Psychological review, 107(3) (2000) 411
  • [26] ANZFA (1997). Identification of food and food components causing frequent and severe adverse reactions. Report of the Australia New Zealand Food Authority Expert Panel on Adverse Reactions to Food. Australia New Zealand Food Authority, Canberra.
  • [27] MAFF (1987). Intolerance to Foods, Food Ingredients and Food Additives. Foodsense Fact Sheet No 12
  • [28] Hannuksela, M. and Haahtela, T. Hypersensitivity reactions to food additives. Allergy 42 (1987) 561-575
  • [29] Bock, S.A. and Aitkins, F.M. Patterns of food hypersensitivity during sixteen years of double-blind, placebo-controlled food challenges. J. Pediatr. 117 (1990) 561-567
  • [30] Adetuyi BO, Dairo JO, Didunyemi MO. Anti-Hyperglycemic Potency of Jatropha Gossypiifolia in Alloxan Induced Diabetes. Biochem Pharmacol 4(5) (2015) 193
  • [31] Kwok, R.H.M. Chinese-restaurant syndrome [Letter]. N. Engl. J. Med. 278 (1968) 796
  • [32] Reif-Lehrer, L. A questionnaire study of the prevalence of Chinese restaurant syndrome. Fed. Proc. 36 (1977) 1617-1623
  • [33] Kerr, G. R., Wu-Lee, M., El-Lozy, M., McGandy, R. and Stare, F.J. Prevalence of the Chinese restaurant syndrome. J. Am. Diet. Assoc. 75 (1979a) 29-33
  • [34] Babatunde O Adetuyi, Foluke K Omolabi, Peace A Olajide, Julius K Oloke. Pharmacological, Biochemical and Therapeutic Potential of Milk Thistle (Silymarin): A Review. World News of Natural Sciences 37 (2021) 75-91
  • [35] Pulce, C., Vial, T., Verdier, F., Testud, F., Nicolas, B. and Descotes, J. The Chinese restaurant syndrome: a reappraisal of monosodium glutamate’s causative role. Adverse Drug React. Toxicol. Rev. 11 (1992) 19-39
  • [36] Geha, R.S., Beiser, A., Ren, C., Patterson, R., Greenberger, P.A., Grammer, L.C., Ditto, A.M., Harris, K.E., Shaughnessy, M.A., Yarnold, P.R., Corren, J. and Saxon, A. Review of alleged reaction to monosodium glutamate and outcome of a multicenter doubleblind placebo-controlled study. In: International Symposium on Glutamate, Proceedings of the symposium held October, 1998 in Bergami, Italy. J. Nutr. 130 (Suppl.) (2000b) 1058S-1062S
  • [37] Ghadimi, H., Kumar, S. and Abaci, F. Studies on monosodium glutamate ingestion. I. Biochemical explanation of the Chinese restaurant syndrome. Biochem. Med. 5 (1971) 447 – 456.
  • [38] Folkers, K., Shizukuishi, S., Willis, R., Scudder, S.L., Takemura, K. and Longenecker, J.B. The biochemistry of vitamin B6 is basic to the cause of the Chinese restaurant syndrome. Hoppe-Seyler’s Z. Physiol. Chem. 365 (1984) 405 – 414.
  • [39] Kenney, R.A. The Chinese restaurant syndrome: an anecdote revisited. Food Chem. Toxicol. 24 (1986) 351 – 354.
  • [40] Price, S.F., Smithson, K.W. and Castell, D.O. (1978). Food sensitivity in reflux esophagitis. Gastroenterology 75 (1978) 240 – 243.
  • [41] Chin, K.W., Garriga, M.M. and Metcalfe, D.D. The histamine content of oriental foods. Food Chem. Toxicol. 27 (1989) 283 – 287.
  • [42] Olubanke O. Ogunlana, Babatunde O. Adetuyi, Miracle Rotimi, Iohor Esalomi, Alaba Adeyemi, Julie Akinyemi, Oluseyi Ogunlana, Oluwatosin Adetuyi, Oluseun Adebisi, Edward Okpata, Roua Baty, Gaber Batiha. Hypoglycemic Activities of Ethanol Seed Extract of Hunteria umbellate (Hallier F.) on Streptozotocin-induced Diabetic Rats. Clinical Phytoscience 7 (2021) (1), 1-9
  • [43] Halpern, B. P. Glutamate and the flavor of foods. The Journal of nutrition, 130(4) (2000) 910S-914S.
  • [44] Babatunde Oluwafemi Adetuyi, Oluwaseun Abraham Adebisi, Oluwatosin Adefunke Adetuyi, Olubanke Olujoke Ogunlana, Pere-Ebi Toloyai, Chukwuebuka Egbuna, Chukwuemelie Zedech Uche, Johra Khan, Obinna Chukwuemeka Uchenna Adumanya, Kingsley C Patrick-Iwuanyanwu. Ficus exasperata Attenuates Acetaminophen-Induced Hepatic Damage via NF-κB Signaling Mechanism in Experimental Rat Model BioMed Research International, (2022).
  • [45] Nichols, P.G. and Jones, S.M. Monosodium glutamate in Western Australian foods. Chemistry in Australia 58 (1991) 556 – 558.
  • [46] Babatunde Oluwafemi Adetuyi, Adebanke E. Ogundipe, Olubanke Olujoke Ogunlana, Chukwuebuka Egbuna, Odoh Uchenna Estella, Abhay Prakash Mishra, Muhammad Akram, Raghu Ram Achar (2022). Banana Peel as a Source of Nutraceuticals. Food and Agricultural Byproducts as Important Source of Valuable Nutraceuticals.1st ed. 2022. Springer, Berlin. xxx, 400 p. Gebunden. ISBN 978-3-030-98759-6
  • [47] Munro, H.N. Factors in the regulation of glutamate metabolism. In: Glutamic Acid: Advances in Biochemistry (Filer, L.J., Garattini, S., Kare, M.R., Reynolds, W.A. and Wurtman, R.J., eds), Raven Press, New York, (1979) pp 55 – 68.
  • [48] BO Adetuyi, PF Adebayo, PA Olajide, OO Atanda, JK Oloke. Involvement of Free Radicals in the Ageing of Cutaneous Membrane. World News of Natural Sciences 43 (2022) 11-37
  • [49] Liebschultz, J., Airoldi, L., Brounstein, M.J. and Chinn, N.G. Regional distribution of endogenous and parenteral glutamate, aspartate, and glutamine in rat brain. Biochem. Pharmacol. 26 (1977) 443 – 446. Lemons, J.A., Adcock, E.W., Jones, M.D., Jr.,
  • [50] Didunyemi MO, Adetuyi BO, Oyebanjo OO (2019). Morinda lucida attenuates acetaminophen-induced oxidative damage and hepatotoxicity in rats, Journal of Biomedical sciences, 8 (2019)
  • [51] Brosnan, J.T. Glutamate, at the interface between amino acid and carbohydrate metabolism. In: International Symposium on Glutamate, Proceedings of the symposium held October, 1998 in Bergami, Italy. J. Nutr. 130 (Suppl.) (2000) 988S – 990S.
  • [52] Babatunde Oluwafemi Adetuyi, Peace Abiodun Olajide, Adefunke Oluwatosin, Julius Kola Oloke. Preventive Phytochemicals of Cancer as Speed Breakers in Inflammatory Signaling. Research Journal of Life Sciences, Bioinformatics, Pharmaceutical and Chemical Sciences 8 (1) (2022) 30-61
  • [53] Awoyelu EH, Oladipo EK, Adetuyi BO, Senbadejo TY, Oyawoye OM, Oloke JK (2020). Phyloevolutionary analysis of SARS-CoV-2 in Nigeria. New Microbes and New Infections 36 (2020) 100717.
  • [54] Neame, K.D. and Wiseman, G. The alanine and oxo acid concentrations in mesenteric blood during the absorption of L-glutamate acid by the small intestine of the dog, cat and rabbit in vivo. J. Physiol. 140 (1958) 148 – 155.
  • [55] Windmueller, H. G. Glutamine utilization by the small intestine. Adv Enzymol Relat Areas Mol Biol, 53(201) (1982) 1982-237.
  • [56] Gaber E. Batiha, Dina A Awad, Abdelazeem M. Algamma, Richard Nyamota, Mir I Wahed, Muhammad Ajmal Shah, Mohammad Nurul Amin, Babatubde O. Adetuyi, Helal F. Hetta, Natalia Cruz-Marins, Niranjan Koirala, Arabinda Ghosh, Jean-Marc Sabatier. Diary-derived and Egg White Proteins in Enhancing Immune System against COVID-19 Frontiers in Nutritionr. (Nutritional Immunology) 8 (2021) 629440
  • [57] Reeds, P.J., Burrin, D.G., Stoll, B., Jahoor, F., Wykes, L., Henry, J. and Frazer, E.M. Enteral glutamate is the preferential source for mucosal glutathione synthesis in fed piglets. Am. J. Physiol. 273 (1997) E408 – E415.
  • [58] Meister, A. Biochemistry of glutamate: glutamine and glutathione. In: Glutamic Acid: Advances in Biochemistry (Filer, L.J., Garattini, S., Kare, M.R., Reynolds, W.A. and Wurtman, R.J., eds), Raven Press, New York, NY, (1979) pp 69 – 84.
  • [59] BO Adetuyi, PA Olajide, EH Awoyelu, OA Adetuyi, OA Adebisi, JK Oloke. Epidemiology and Therapeutic measure for COVID-19; A review. African Journal of Reproductive Health June 2020 (Special Edition on COVID-19); 24 (2) (2020)142
  • [60] Anum Nazir, Nizwa Itrat, Aleena Shahid, Zain Mushtaq, Surajudeen Abiola Abdulrahman, Chukwuebuka Egbuna, Babatunde Oluwafemi Adetuyi, Johra Khan, Chukwuemelie Zedech Uche, Pere-Ebi Yabrade Toloyai. Orange Peel as a Source of Nutraceuticals. Food and Agricultural Byproducts as Important Source of Valuable Nutraceuticals.1st ed. 2022 Springer, Berlin. xxx, 400 p. Gebunden. ISBN 978-3-030-98759-6
  • [61] Bizzi, A., Veneroni, E., Salmona, M. and Garattini, S. Kinetics of monosodium glutamate in relation to its neurotoxicity. Toxicol. Lett. 1 (1977) 123-130
  • [62] Stegink, L.D., Filer, L.J., Jr., Baker, G.L., Mueller, S.M. and Wu-Rideout, M.Y. –C. Comparative metabolism of glutamate in the mouse, monkey and man. In: Glutamic Acid: Advances in Biochemistry (Filer, L.J., Garattini, S., Kare, M.R., Reynolds, W.A. and Wurtman, R.J., eds), Raven Press, New York, NY, (1979a) pp 85 – 102.
  • [63] Olubanke O. Ogunlana, Oluseyi E. Ogunlana, Tobi S. Adekunbi, Babatunde O. Adetuyi, Bose E. Adegboye, and Franklyn N. Iheagwam. Anti-inflammatory Mechanism of Ruzu Bitters on Diet-Induced Nonalcoholic Fatty Liver Disease in Male Wistar Rats. Evidence-Based Complementary and Alternative Medicine, (2020)
  • [64] Stegink, L.D., Baker, G.L. and Filer, L.J., Jr. Modulating effect of Sustagen on plasma glutamate concentration in humans ingesting monosodium L-glutamte. Am. J. Clin. Nutr. 37 (1983a) 194-200
  • [65] Olubanke O Ogunlana, Babatunde O Adetuyi, Elohor F Esalomi, Miracle I Rotimi, Jacob O Popoola, Oluseyi E Ogunlana, Oluwatosin A Adetuyi. Antidiabetic and Antioxidant Activities of the Twigs of Andrograhis paniculata on Streptozotocin-Induced Diabetic Male Rats. BioChem 1(3) (2021) 238-249
  • [66] Stegink, L.D., Filer, L.J., Jr. and Baker, G.L. (1983c). Plasma amino acid concentration in normal adults fed meals with added monosodium L-glutamate and aspartame. J. Nutr. 113: 1851-1860
  • [67] Babatunde Oluwafemi Adetuyi, Tolulope Olamide Okeowo, Oluwatosin Adefunke Adetuyi, Oluwaseun Abraham Adebisi, Olubanke Ogunlana, Oyeyemi Janet Oretade, Najat Marraiki, Amany Magdy Beshbishy, Nermeen N. Welson, Gaber ElSaber Batiha (2020). Ganoderma lucidum from red mushroom attenuates formaldehyde- induced liver damage in experimental male rat model. Biology, 9(10) (2020) 313
  • [68] Stegink, L.D., Filer, L.J., Jr., Baker, G.L. and Bell, E.F. Effect of sucrose ingestion on plasma glutamate concentrations in humans administered monosodium L-glutamate. Am. J. Clin. Nutr. 42 (1986) 220-225
  • [69] Olubanke O. Ogunlana, Oluseyi E. Ogunlana, Jacob O. Popoola, Babatunde O. Adetuyi, Tobi S. Adekunbi, Opetoritse L. David, Oluwaseye J. Adeleye, Stephanie A. Udeogu, Alaba O. Adeyemi. Twigs of Andrographis paniculata (Burn. F) Nees attenuates Carbon Tetrachloride (CCl4) Induced Liver Damage in Wistar Albino Rats. RASAYAN Journal of Chemistry 14(4) (2021) 2598-2603
  • [70] Pitkin, R.M., Reynolds, W.A., Stegink, L.D. and Filer, L.J., Jr. Glutamate metabolism and placental transfer in pregnancy. In: Glutamic Acid: Advances in Biochemistry (Filer, L.J., Garattini, S., Kare, M.R., Reynolds, W.A. and Wurtman, R.J., eds), Raven Press, New York, NY, (1979) pp 103-110
  • [71] MO Didunyemi, BO Adetuyi, IA, Oyewale. Inhibition of lipid peroxidation and in-vitro antioxidant capacity of aqueous, acetone and methanol leaf extracts of green and red Acalypha wilkesiana Muell Arg. Int J Biol Med Res, 11(3): (2020) 7089-7094
  • [72] Rassin, D.K., Sturman, J.A. and Gaull, G.E. Taurine and other amino acids in milk and other mammals. Early Hum. Dev. 2 (1978) 1-13
  • [73] Babatunde Oluwafemi Adetuyi, Pere-Ebi Yabrade Toloyai, Evelyn Tarela Ojugbeli, Oyetola Tolulope Oyebanjo, Oluwatosin Adefunke Adetuyi, Chukwuemelie Zedech Uche, Michael Chinedu Olisah, Obinna Chukwuemeka Uchenna Adumanya, Chukwudi Jude, Johra Khan Chikwendu, Muhammad Akram, Chinaza Godswill Awuchi, Chukwuebuka Egbuna. Neurorestorative Roles of Microgliosis and Astrogliosis in Neuroinflammation and Neurodegeneration. Scicom Journal of Medical and Applied Medical Sciences 1(1) (2021) 1-5
  • [74] Battaglia, F.C. Glutamine and glutamate exchange between the fetal liver and the placenta. In: International Symposium on Glutamate, Proceedings of the symposium held October, 1998 in Bergami, Italy. J. Nutr. 130 (Suppl.) (2000) 974S – 977S
  • [75] Olubanke O. Ogunlana, Babatunde O. Adetuyi, Tobi S. Adekunbi, Bose E. Adegboye, Franklyn N. Iheagwam, Oluseyi E. Ogunlana. Ruzu bitters ameliorates high–fat diet induced non-alcoholic fatty liver disease in male Wistar rats. Journal of Pharmacy and Pharmacognosy Research 9(3) (2021) 251-260
  • [76] Hayashi, S., Sanada, K., Sagama, N., Yamada, N. and Kido, K. Umbilical vein-artery differences of plasma amino acids in the last trimester of human pregnancy. Biol. Neonate 34 (1978) 11-18
  • [77] MO Didunyemi, BO Adetuyi, IA, Oyewale. Inhibition of lipid peroxidation and in-vitro antioxidant capacity of aqueous, acetone and methanol leaf extracts of green and red Acalypha wilkesiana Muell Arg. Int J Biol Med Res 11(3) (2020) 7089-7094
  • [78] Caccia, S., Garattini, S., Ghezzi, P. and Zanini, M.G. Plasma and brain levels of glutamate and pyroglutamate after oral monosodium glutamate to rats. Toxicol. Lett. 10 (1982) 169-175
  • [79] Paula-Peace O James-Okoro, Franklyn N Iheagwam, Mariam I Sholeye, Itoroobong A Umoren, Babatunde O Adetuyi, Adebanke E Ogundipe, Adefoyeke A Braimah, Tobi S Adekunbi, Oluseyi E Ogunlana, Olubanke O Ogunlana. Phytochemical and in vitro antioxidant assessment of Yoyo bitters. World News of Natural Sciences 37 (2021) 1-17
  • [80] Liebschutz, J., Airoldi, L., Brownstein, M. J., Chinn, N. G., & Wurtman, R. J. Regional distribution of endogenous and parenteral glutamate, aspartate and glutamine in rat brain. Biochemical Pharmacology, 26(5) (1977) 443-446.
  • [81] BO Adetuyi, OA Adebisi, EH Awoyelu, OA Adetuyi, OO Ogunlana. Phytochemical and Toxicological effect of Ethanol extract of Heliotropium indicum on Liver of Male Albino Rats. Letters in Applied NanoBioscience 10(2) (2020) 2085-2095

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