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2013 | 67 | 1 | 33–39
Article title

Znaczenie czynników genetycznych w chorobie niedokrwiennej serca

Title variants
The genetic determinants of coronary heart disease
Languages of publication
Coronary artery disease is multifactorial. In recent times due to the development of modern molecular biology techniques, candidate gene polymorphisms related to lipid metabolism the renin–angiotensin–aldosterone system and the regulation of coagulation and fibrinolysis as well as inflammatory response, have become a research topic. This article provides an overview of the most frequently studied polymorphisms.
Choroba niedokrwienna serca ma charakter wieloczynnikowy. W ostatnim czasie ze względu na rozwój technik z zakresu biologii molekularnej tematem badań stały się polimorfizmy genów kandydatów, związanych z metabolizmem lipidów, z układem renina–angiotesyna–aldosteron (RAA), regulacją krzepnięcia i fibrynolizy oraz reakcją zapalną. W pracy przedstawiono przegląd wyników najczęściej badanych polimorfizmów.

Physical description
  • Katedra i Zakład Ogólnej Biologii Lekarskiej Wydziału Lekarskiego w Zabrzu z Oddziałem Lekarsko-Dentystycznym Śląskiego Uniwersytetu Medycznego w Katowicach
  • Katedra i Zakład Ogólnej Biologii Lekarskiej Wydziału Lekarskiego w Zabrzu z Oddziałem Lekarsko-Dentystycznym Śląskiego Uniwersytetu Medycznego w Katowicach ul. Jordana 19 41-808 Zabrze tel./fax + 48 32 272 21 71,
  • Katedra i Zakład Ogólnej Biologii Lekarskiej Wydziału Lekarskiego w Zabrzu z Oddziałem Lekarsko-Dentystycznym Śląskiego Uniwersytetu Medycznego w Katowicach
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